{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:32:32Z","timestamp":1777379552484,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T00:00:00Z","timestamp":1567123200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>\n                    Surprisingly, more new unique recombinant forms (URFs) of CRF01_AE\/CRF07_BC recombinant viruses were found in Tianjin, China, recently. Here we identified another novel HIV-1 recombinant virus (TJ20170315) isolated from an HIV-1 positive man who has sex with men in Tianjin, China. Phylogenetic analysis of the near full-length genome of TJ20170315 showed that it formed a monophyletic branch within the cluster of CRF01_AE reference sequences. Recombinant analysis showed that the virus kept the CRF01_AE parental backbone, and one CRF07_BC segment was inserted into\n                    <jats:italic toggle=\"yes\">gag<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">pol<\/jats:italic>\n                    genes of the CRF01_AE backbone. Nowadays, multiple kinds of circulating recombinant forms (CRFs) and URFs were identified among men who has sex with men in China. The emergency of URFs highlights the complexity of HIV-1 infection in Tianjin, China, and implies that the next new CRF and HIV-1 epidemic are coming on the road.\n                  <\/jats:p>","DOI":"10.1089\/aid.2019.0071","type":"journal-article","created":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T07:18:50Z","timestamp":1559373530000},"page":"865-869","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Another Near Full-Length Sequence of an HIV-1 CRF01_AE\/CRF07_BC Recombinant Virus from a Man Who Has Sex with Men in Tianjin, China"],"prefix":"10.1177","volume":"35","author":[{"given":"Zehua","family":"Zhou","sequence":"first","affiliation":[{"name":"Nankai University Second People's Hospital, School of Medicine, Nankai University, Tianjin, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Ma","sequence":"additional","affiliation":[{"name":"Nankai University Second People's Hospital, School of Medicine, Nankai University, Tianjin, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Feng","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weidong","family":"Ou","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiming","family":"Shao","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China."},{"name":"School of Medicine, Nankai University, Tianjin, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Wei","sequence":"additional","affiliation":[{"name":"Nankai University Second People's Hospital, School of Medicine, Nankai University, Tianjin, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,8,30]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01841-16"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2011.12.001"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2009.05.023"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/088922299311754"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.23.11286-11295.2000"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)79316-8"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)92304-3"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047289"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328360db2d"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00399-08"},{"key":"e_1_3_3_12_2","first-page":"8","article-title":"[Subtype and sequence analysis of the C2-V3 region of gp120 genes among human immunodeficiency virus infected IDUs in Ruili epidemic area of Yunnan Province of China]","volume":"11","author":"Guan Y","year":"1997","unstructured":"Guan Y, , Chen J, , Shao Y, et al.: [Subtype and sequence analysis of the C2-V3 region of gp120 genes among human immunodeficiency virus infected IDUs in Ruili epidemic area of Yunnan Province of China]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi, 1997; 11: 8\u201312 (Article in Chinese).","journal-title":"Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi"},{"key":"e_1_3_3_13_2","first-page":"217","article-title":"[Subtype and sequence analysis of the C2-V3 region of gp120 genes among HIV-1 strains in Hubei province]","volume":"18","author":"Li YW","year":"1997","unstructured":"Li YW, , Shao YM, , Luo XG: [Subtype and sequence analysis of the C2-V3 region of gp120 genes among HIV-1 strains in Hubei province]. Zhonghua Liu Xing Bing Xue Za Zhi, 1997; 18:217\u2013219 (Article in Chinese).","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep19279"},{"key":"e_1_3_3_15_2","unstructured":"National Health and Family Planning Commission of China:. 2015 China AIDS Response Progress Report. Available at http:\/\/unaids.org.cn\/en\/index\/Document_view.asp?id=874. accessed March 2019."},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037211"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2011-050295"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cr.7290359"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/485576a"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep11205"}],"container-title":["AIDS Research and Human Retroviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/aid.2019.0071","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2019.0071","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2019.0071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:14:47Z","timestamp":1777367687000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/aid.2019.0071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,30]]},"references-count":19,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1089\/aid.2019.0071"],"URL":"https:\/\/doi.org\/10.1089\/aid.2019.0071","relation":{},"ISSN":["0889-2229","1931-8405"],"issn-type":[{"value":"0889-2229","type":"print"},{"value":"1931-8405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,30]]}}}