{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:37:24Z","timestamp":1777379844195,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:p>Unique recombinant forms (URFs) are more likely developed among HIV-1 infections through men who have sex with men (MSM) because of cocirculation of multiple subtypes. In this study, two novel URFs deriving from two HIV-positive subjects (HB010014, HB010063) were identified in Shijiazhuang, Hebei province, China, and two sequences formed a distinct monophyletic cluster. Further recombination analysis showed that of two new URFs were consisted of circulating recombinant form (CRF)01_AE and CRF07_BC. The subregion phylogenetic analysis indicated that CRF01_AE segments were traced back to cluster 4 of CRF01_AE strains, which were prevalent among HIV-1 infections through MSM in China. New URFs being developing gradually and spreading released that more and more novel recombinant strains of HIV-1 could be developed, which means that the past prevention strategies need to be adjusted.<\/jats:p>","DOI":"10.1089\/aid.2021.0100","type":"journal-article","created":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:56:31Z","timestamp":1630457791000},"page":"978-984","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Near Full-Length Genomic Characterization of Two Novel HIV-1 Unique Recombinant Forms (CRF01_AE\/CRF07_BC) Among Men Who Have Sex with Men in Shijiazhuang City, Hebei Province, China"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3415-0894","authenticated-orcid":false,"given":"Leilei","family":"Han","sequence":"first","affiliation":[{"name":"School of Public Health, North China University of Science and Technology, Tangshan, China."},{"name":"Department of Laboratory Medicine, North China University of Science and Technology, The Fifth Hospital of Shijiazhuang, Shijiazhuang, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanping","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, North China University of Science and Technology, The Fifth Hospital of Shijiazhuang, Shijiazhuang, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Jia","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingwan","family":"Han","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianyi","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolin","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongjian","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingyun","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianhua","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, North China University of Science and Technology, The Fifth Hospital of Shijiazhuang, Shijiazhuang, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojing","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, North China University of Science and Technology, The Fifth Hospital of Shijiazhuang, Shijiazhuang, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuhui","family":"He","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, The Second Hospital of Xingtai, Xingtai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haichun","family":"Liu","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, Zhangjiakou Infectious Disease Hospital, Zhangjiakou, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogen and Biosecurity, Department of AIDS Research, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erhei","family":"Dai","sequence":"additional","affiliation":[{"name":"School of Public Health, North China University of Science and Technology, Tangshan, China."},{"name":"Department of Laboratory Medicine, North China University of Science and Technology, The Fifth Hospital of Shijiazhuang, Shijiazhuang, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,12,15]]},"reference":[{"key":"e_1_3_4_2_2","unstructured":"UNAIDS. Available at https:\/\/www.unaids.org\/en\/resources\/fact-sheet accessed April10 2021."},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12985-020-1281-y"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0000000000000534"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.09.007"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2020.0002"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.00061"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2018.0226"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep19279"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2019.0199"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2019.09.022"}],"container-title":["AIDS Research and Human Retroviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/aid.2021.0100","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2021.0100","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2021.0100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:15:45Z","timestamp":1777367745000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/aid.2021.0100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":10,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1089\/aid.2021.0100"],"URL":"https:\/\/doi.org\/10.1089\/aid.2021.0100","relation":{},"ISSN":["0889-2229","1931-8405"],"issn-type":[{"value":"0889-2229","type":"print"},{"value":"1931-8405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]}}}