{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:06:47Z","timestamp":1787501207592,"version":"build-2736575974"},"reference-count":74,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:p>\n                    The introduction of highly active combined antiretroviral therapy (cART) has changed the management of HIV\/AIDS, which is recognized as a chronic disease with relevant aspects, such as adherence and quality of life. This study aimed to compare clinical and demographic characteristics and health-related quality of life in people with adherence and non-adherence to cART. A cross-sectional study was carried out with 200 participants. The instruments used were the Adherence Follow-up Questionnaire, the Beck Depression Inventory-II, the 36-Item Short Form Health Survey and the WHOQOL-HIV BREF. Poisson regression was applied to obtain estimates of adjusted prevalence ratios (PR\n                    <jats:sub>adj<\/jats:sub>\n                    ). Individuals lacking therapeutic support were more likely to be non-adherent than those with proper support (PR: 1.79). The health-related quality of life of individuals with non-adherence was 4% lower (PR\u2009=\u20090.96) in the general health domain than individuals with adherence. Non-adherence to cART was associated with lower quality of life in the general health domain and no therapeutic support.\n                  <\/jats:p>","DOI":"10.1089\/aid.2021.0233","type":"journal-article","created":{"date-parts":[[2022,4,23]],"date-time":"2022-04-23T02:56:12Z","timestamp":1650682572000},"page":"660-669","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Quality of Life and Antiretroviral Therapy Adherence: A Cross-Sectional Study in Colombia"],"prefix":"10.1177","volume":"38","author":[{"given":"M\u00f3nica","family":"Narv\u00e1ez","sequence":"first","affiliation":[{"name":"Post Graduation Program in Medicine and Health (PPgMS), Federal University of Bahia, Salvador, Brazil."},{"name":"Research Laboratory in Infectious Diseases (LAPI), University Hospital Complex Professor Edgard Santos, Federal University of Bahia, Salvador, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliane","family":"Lins-Kusterer","sequence":"additional","affiliation":[{"name":"Post Graduation Program in Medicine and Health (PPgMS), Federal University of Bahia, Salvador, Brazil."},{"name":"Research Laboratory in Infectious Diseases (LAPI), University Hospital Complex Professor Edgard Santos, Federal University of Bahia, Salvador, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliet","family":"Valdelamar-Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Post Graduation Program in Medicine and Health (PPgMS), Federal University of Bahia, Salvador, Brazil."},{"name":"Research Laboratory in Infectious Diseases (LAPI), University Hospital Complex Professor Edgard Santos, Federal University of Bahia, Salvador, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4673-6991","authenticated-orcid":false,"given":"Carlos","family":"Brites","sequence":"additional","affiliation":[{"name":"Post Graduation Program in Medicine and Health (PPgMS), Federal University of Bahia, Salvador, Brazil."},{"name":"Research Laboratory in Infectious Diseases (LAPI), University Hospital Complex Professor Edgard Santos, Federal University of Bahia, Salvador, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,8,5]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/09540120902803158"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61809-7"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200003303421303"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105243"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200106150-00015"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00126334-200212153-00005"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200411050-00011"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000433240.78739.30"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000252"},{"key":"e_1_3_5_11_2","unstructured":"UNAIDS: 90-90-90. An ambitious treatment target to help end the AIDS epidemic [Internet]. Geneva 2014. 33 p. Available at https:\/\/www.unaids.org\/en\/resources\/documents\/2017\/90-90-90 accessed August12 2021."},{"key":"e_1_3_5_12_2","unstructured":"World Health Organization: Draft global health sector strategies. HIV 2016\u20132021: report by the Secretariat. Executive Board 138. [Internet] 2016. Available at https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/250669\/B138_29-en.pdf?sequence=1&isAllowed=y accessed August13 2021."},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-016-0640-4"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0277-9536(95)00112-K"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-017-0778-6"},{"key":"e_1_3_5_16_2","unstructured":"Bad\u00eda L Lara SN: Health-related quality of life in patients with HIV (in Spanish). Health Outcomes Research Europe Group Barcelona 2002. https:\/\/www.sefh.es\/bibliotecavirtual\/4_AF_VIH_2004\/2_calidad_vida.pdf accessed August18 2021."},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10880-019-09657-9"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2019.08.001"},{"key":"e_1_3_5_19_2","unstructured":"World Health Organization: WHOQOL-HIV instrument: scoring and coding for the WHOQOL-HIV instruments: users manual [Internet] 2012 revised. Geneva: World Health Organization. Available at https:\/\/apps.who.int\/iris\/handle\/10665\/77776 accessed March18 2022."},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-013-0040-4"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2019.06.005"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1016668802328"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-006-9151-7"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-018-1998-x"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2017.04.004"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1080\/09540120412331305098"},{"key":"e_1_3_5_27_2","first-page":"A133","article-title":"Viral load suppression, mental health, and quality of life among people living with HIV in South Carolina","volume":"81","author":"Cho H","year":"2019","unstructured":"Cho H, , Jiang Y, , Li X: Viral load suppression, mental health, and quality of life among people living with HIV in South Carolina. Psychosom Med [Internet], 2019; 81:A133.","journal-title":"Psychosom Med [Internet]"},{"key":"e_1_3_5_28_2","unstructured":"ACTG: Adherence follow up questionnaire [Internet] 2001. at https:\/\/www.frontierscience.org\/apps\/cfmx\/apps\/common\/QOLAdherenceForms\/resources\/actg\/forms\/english\/ql0702.pdf accessed September20 2021."},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1080\/09540120050042891"},{"key":"e_1_3_5_30_2","unstructured":"World Health Organization. Adherence to long-term therapies: evidence for action\/[edited by Eduardo Sabate\u00b4] [Internet]. Geneva: World Health Organization 2003. 196 p. Available at https:\/\/apps.who.int\/iris\/handle\/10665\/42682 accessed November19 2021."},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1080\/09540120600842516"},{"key":"e_1_3_5_32_2","first-page":"239","article-title":"Spanish adaptation of the Beck Depression Inventory-II (BDI-II): 1","volume":"29","author":"Sanz ME","year":"2003","unstructured":"Sanz ME, , V\u00e1zquez CJN: Spanish adaptation of the Beck Depression Inventory-II (BDI-II): 1. Psychometricproperties with university students (in Spanish). An\u00e1lisis y Modif Conduct, 2003; 29:239\u2013288.","journal-title":"Psychometricproperties with university students (in Spanish). An\u00e1lisis y Modif Conduct"},{"key":"e_1_3_5_33_2","first-page":"249","article-title":"The spanish adaptation of Beck's Depression Inventory-II (BDI-II): 2","volume":"14","author":"Sanz Perdig\u00f3n AL","year":"2003","unstructured":"Sanz Perdig\u00f3n AL, , V\u00e1zquez CJ: The spanish adaptation of Beck's Depression Inventory-II (BDI-II): 2. Psychometricproperties in the general population (in Spanish). Cl\u00ednica y Salud [Internet] 2003; 14 :249\u2013280.","journal-title":"Psychometricproperties in the general population (in Spanish)"},{"key":"e_1_3_5_34_2","volume-title":"Manual for the Beck Depression Inventory Second Edition (BDI-II)","author":"Beck AT","unstructured":"Beck AT, , Brown GH, , Steer RA: Manual for the Beck Depression Inventory Second Edition (BDI-II). Psychol Corp., San Antonio, 1996."},{"key":"e_1_3_5_35_2","unstructured":"Alonso JC: The Spanish version of the SF-36 Health Survey (Version 2) (in Spanish). Inst Munic d\u00b4Investigaci\u00f3 M\u00e8dica [Internet] 2003. Available at https:\/\/criticalcarenutrition.com\/docs\/reenergize_def\/SF-36Spanish.pdf accessed July17 2021."},{"key":"e_1_3_5_36_2","first-page":"771","article-title":"The Spanish version of the SF-36 Health Survey (the SF-36 health questionnaire): aninstrument for measuring clinical results (in Spanish)","volume":"104","author":"Alonso Prieto L","year":"1995","unstructured":"Alonso Prieto L, , Anto JMJ: The Spanish version of the SF-36 Health Survey (the SF-36 health questionnaire): aninstrument for measuring clinical results (in Spanish). Med Clin, 1995; 104:771\u2013776.","journal-title":"Med Clin"},{"key":"e_1_3_5_37_2","doi-asserted-by":"crossref","unstructured":"Ware J Dewey JKM: How to Score Version 2 of the SF-36\u00ae Health Survey. Lincoln Quality Metric Incorporated. 2000 (in Spanish).","DOI":"10.1097\/00007632-200012150-00008"},{"key":"e_1_3_5_38_2","doi-asserted-by":"publisher","DOI":"10.1080\/09540120412331290194"},{"key":"e_1_3_5_39_2","doi-asserted-by":"publisher","DOI":"10.1037\/1040-3590.10.2.83"},{"key":"e_1_3_5_40_2","first-page":"16","article-title":"Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio","volume":"37","author":"Barros AJD","year":"2003","unstructured":"Barros AJD, , Hirakata VN: Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio. BMC Med Res Methodol [Internet], 2003; 37:16\u201321.","journal-title":"BMC Med Res Methodol [Internet]"},{"key":"e_1_3_5_41_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-89102008000600003"},{"key":"e_1_3_5_42_2","doi-asserted-by":"publisher","DOI":"10.1207\/S15327752JPA8001_18"},{"key":"e_1_3_5_43_2","volume-title":"Psychometric Theory","author":"Nounally JC","unstructured":"Nounally JC, , Bernstein IH: Psychometric Theory, 3rd ed. McGraw- Hill, New York, 1994."},{"key":"e_1_3_5_44_2","first-page":"83","article-title":"Factores relacionados con la adherencia al tratamiento farmacol\u00f3gico para el VIH\/SIDA","volume":"29","author":"Ar\u00e9valo MTV","year":"2013","unstructured":"Ar\u00e9valo MTV, , Guti\u00e9rrez OLG, , Mar\u00edan HFM, et al.: Factores relacionados con la adherencia al tratamiento farmacol\u00f3gico para el VIH\/SIDA. Salud Uninorte [Internet], 2013; 29:83\u201395.","journal-title":"Salud Uninorte [Internet]"},{"key":"e_1_3_5_45_2","doi-asserted-by":"publisher","DOI":"10.15446\/revfacmed.v65n3.55535"},{"key":"e_1_3_5_46_2","doi-asserted-by":"publisher","DOI":"10.1080\/16549716.2018.1441783"},{"key":"e_1_3_5_47_2","doi-asserted-by":"publisher","DOI":"10.15288\/jsad.2017.78.716"},{"key":"e_1_3_5_48_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-013-0583-0"},{"key":"e_1_3_5_49_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13033-020-00430-2"},{"key":"e_1_3_5_50_2","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/5414072"},{"key":"e_1_3_5_51_2","first-page":"1","article-title":"Impact and correlates of sub-optimal social support among patients in HIV care","author":"Fredericksen RJ","year":"2021","unstructured":"Fredericksen RJ, , Gibbons LE, , Fitzsimmons E, et al.: Impact and correlates of sub-optimal social support among patients in HIV care. AIDS Care, 2021; 1\u201311.","journal-title":"AIDS Care"},{"key":"e_1_3_5_52_2","first-page":"307","article-title":"Factors associated with adherence to anti-retroviral therapy among people living with HIV\/AIDS at Wangaya Hospital in Denpasar, Bali, Indonesia: A cross-sectional study","volume":"11","author":"Suryana K","year":"2019","unstructured":"Suryana K, , Suharsono H, , Antara I: Factors associated with adherence to anti-retroviral therapy among people living with HIV\/AIDS at Wangaya Hospital in Denpasar, Bali, Indonesia: A cross-sectional study. HIV AIDS, 2019; 11:307\u2013312.","journal-title":"HIV AIDS"},{"key":"e_1_3_5_53_2","doi-asserted-by":"publisher","DOI":"10.1177\/1055329003252424"},{"key":"e_1_3_5_54_2","first-page":"130","article-title":"[Adherence to antiretroviral drug therapy","volume":"119","author":"Puigvent\u00f3s F","year":"2002","unstructured":"Puigvent\u00f3s F, , Riera M, , Delibes C, et al.: [Adherence to antiretroviral drug therapy. A systematic review]. Med Clin, 2002; 119:130\u2013137.","journal-title":"A systematic review]. Med Clin"},{"key":"e_1_3_5_55_2","doi-asserted-by":"publisher","DOI":"10.1097\/00126334-200212153-00007"},{"key":"e_1_3_5_56_2","doi-asserted-by":"publisher","DOI":"10.7705\/biomedica.v31i4.422"},{"key":"e_1_3_5_57_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2008.0173"},{"key":"e_1_3_5_58_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-020-02865-w"},{"key":"e_1_3_5_59_2","doi-asserted-by":"publisher","DOI":"10.1080\/13548506.2019.1616101"},{"key":"e_1_3_5_60_2","doi-asserted-by":"publisher","DOI":"10.25100\/cm.v41i3.706"},{"key":"e_1_3_5_61_2","doi-asserted-by":"publisher","DOI":"10.1080\/09540121.2019.1710449"},{"key":"e_1_3_5_62_2","doi-asserted-by":"publisher","DOI":"10.4103\/2249-4863.222016"},{"key":"e_1_3_5_63_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40249-017-0364-5"},{"key":"e_1_3_5_64_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jana.2009.02.002"},{"key":"e_1_3_5_65_2","doi-asserted-by":"publisher","DOI":"10.1590\/0047-2085000000002"},{"key":"e_1_3_5_66_2","doi-asserted-by":"publisher","DOI":"10.1590\/0104-1169.3534.2508"},{"issue":"2","key":"e_1_3_5_67_2","first-page":"539","article-title":"[Adherence to HAART, quality of life and psychopathological symptoms among HIV\/AIDS infected patients]","volume":"24","author":"Margalho R","year":"2011","unstructured":"Margalho R, , Pereira M, , Ouakinin S, et al.: [Adherence to HAART, quality of life and psychopathological symptoms among HIV\/AIDS infected patients]. Acta Med Port, 2011; 24(Suppl. 2):539\u2013548.","journal-title":"Acta Med Port"},{"key":"e_1_3_5_68_2","doi-asserted-by":"publisher","DOI":"10.1080\/09540121.2019.1576846"},{"key":"e_1_3_5_69_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0135705"},{"key":"e_1_3_5_70_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-019-1208-8"},{"key":"e_1_3_5_71_2","first-page":"76","article-title":"Quality of life, its importance and how to measure it (in Spanish)","volume":"21","author":"Tuesca Molina R","year":"2005","unstructured":"Tuesca Molina R: Quality of life, its importance and how to measure it (in Spanish). Salud Uninorte, 2005; 21:76\u201386.","journal-title":"Salud Uninorte"},{"key":"e_1_3_5_72_2","first-page":"134","article-title":"Bio-social factors and perceptions of life with quality: a challenge to the adherence of HIV patients to the antirretroviral treatment (in Spanish)","volume":"26","author":"Estrada MJH","year":"2008","unstructured":"Estrada MJH, , Mart\u00ednez PAG, et al.: Bio-social factors and perceptions of life with quality: a challenge to the adherence of HIV patients to the antirretroviral treatment (in Spanish). Rev Fac Nac Salud P\u00fablica, 2008; 26:134\u2013142.","journal-title":"Rev Fac Nac Salud P\u00fablica"},{"key":"e_1_3_5_73_2","first-page":"33","article-title":"Quality of life, adherence and clinical indicators among people living with HIV (in Spanish)","author":"Primeira MR","year":"2020","unstructured":"Primeira MR, , Santos WM dos, , de Paula CC, et al.: Quality of life, adherence and clinical indicators among people living with HIV (in Spanish). Acta Paul Enferm [Internet], 2020; 33.","journal-title":"Acta Paul Enferm [Internet]"},{"key":"e_1_3_5_74_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080633"},{"key":"e_1_3_5_75_2","first-page":"101","article-title":"Adherence to treatment in HIV\/AIDS infection","volume":"11","author":"Varela Ar\u00e9valo MT","year":"2008","unstructured":"Varela Ar\u00e9valo MT, , Correa S\u00e1nchez D, , Salazar Torres IC: Adherence to treatment in HIV\/AIDS infection. Theoretical and methodological considerations for dealing with this problem (in Spanish). Acta Colomb Psicol [Internet], 2008; 11:101\u2013114.","journal-title":"Theoretical and methodological considerations for dealing with this problem (in Spanish). Acta Colomb Psicol [Internet]"}],"container-title":["AIDS Research and Human Retroviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/aid.2021.0233","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2021.0233","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2021.0233","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:16:33Z","timestamp":1777367793000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/aid.2021.0233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":74,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1089\/aid.2021.0233"],"URL":"https:\/\/doi.org\/10.1089\/aid.2021.0233","relation":{},"ISSN":["0889-2229","1931-8405"],"issn-type":[{"value":"0889-2229","type":"print"},{"value":"1931-8405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8]]}}}