{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T19:40:53Z","timestamp":1792698053469,"version":"4.5.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>\n                    This survey aimed to understand how far the Italian infectious diseases (ID) specialists are confident in the \u201cUndetectable\u2009=\u2009Untransmittable\u201d (U\u2009=\u2009U) message and translate this concept into clinical practice. An anonymous survey was distributed by e-mail to 286 clinicians to collect their opinions regarding six situations potentially at risk of HIV transmission between virologically suppressed patients and seronegative individuals who possibly require postexposure prophylaxis (PEP). Overall, 51% of ID specialists deemed zero risk of HIV transmission through condomless sex for undetectable patients. This answer was more frequent among HIV specialists (30% vs. 21%,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u2009.01) and clinicians working in teaching hospitals (35% vs. 16%,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u2009.03). Remarkably, 61% of participants would advise taking PEP for the HIV-negative partner in case of sexual intercourse with a seropositive person with a recent blip occurrence or absence of an HIV RNA test performed within the last 6 months (63%). Seventy-three percent of respondents deemed it essential to know patients' history of adherence to interpreting an HIV RNA test, regardless of its timing. When applying the U\u2009=\u2009U concept to daily clinical decisions, we observed an overall cautious attitude among physicians. Concerns mainly regarded the timing of the last HIV RNA test to the exposure event, especially in the absence of details on the patient's adherence. Wider diffusion and application of the U\u2009=\u2009U message are needed.\n                  <\/jats:p>","DOI":"10.1089\/aid.2022.0056","type":"journal-article","created":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T03:30:28Z","timestamp":1663039828000},"page":"847-855","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Perceptions of U\u2009=\u2009U Among Italian Infectious Diseases Specialists: A Nationwide Survey on Providers' Attitudes Toward the Risk of HIV Transmission in Virologically Suppressed Patients"],"prefix":"10.1177","volume":"38","author":[{"given":"Diego","family":"Ripamonti","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, ASST Papa Giovanni XXIII, Bergamo, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9896-489X","authenticated-orcid":false,"given":"Mariacristina","family":"Poliseno","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Mazzola","sequence":"additional","affiliation":[{"name":"Department of Sciences for Health Promotion \u201cG. D'Alessandro,\u201d University of Palermo, Palermo, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Colletti","sequence":"additional","affiliation":[{"name":"Department of Medicinal Clinics and Emerging Diseases, \u201cPaolo Giaccone\u201d Policlinic University Hospital, Palermo, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Di Biagio","sequence":"additional","affiliation":[{"name":"Unit of Infectious Diseases, Department of Health Sciences, San Martino Policlinico Hospital, University of Genoa, Genoa, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedetto Maurizio","family":"Celesia","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Biomedicine, Division of Infectious Diseases, University of Catania, Catania, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Gori","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, San Gerardo Hospital, University of Milano-Bicocca, Milan, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Bellagamba","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Unit, National Institute for Infectious Disease \u201cL. Spallanzani,\u201d Roma, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giordano","family":"Madeddu","sequence":"additional","affiliation":[{"name":"Unit of Infectious Diseases, Department of Clinical and Experimental Medicine, University of Sassarim Sassari, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Nozza","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0375-9990","authenticated-orcid":false,"given":"Stefano","family":"Rusconi","sequence":"additional","affiliation":[{"name":"Divisione Clinicizzata di Malattie Infettive, DIBIC L. Sacco, Universit\u00e0 degli Studi di Milano, Milan, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Cascio","sequence":"additional","affiliation":[{"name":"Infectious Disease Unit, Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), Policlinico \u201cP. Giaccone,\u201d University of Palermo, Palermo, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Lo Caputo","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,11,3]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.5148"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30418-0"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1600693"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001158"},{"key":"e_1_3_4_6_2","unstructured":"Prevention Access Campaign. Consensus statement. 2019. Risk of sexual transmission of HIV from a person living with HIV who has an undetectable viral load. Available from: https:\/\/www.preventionaccess.org\/consensus [Last accessed: April 14 2022]."},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(19)30030-X"},{"key":"e_1_3_4_8_2","unstructured":"Gupta N. 2019 BHIVA Pre-conference Meeting: Important Challenges. BHIVA's position on U\u2009=\u2009U an update. Available from: https:\/\/www.bhiva.org\/AnnualConference2019Presentations [Last accessed: April 14 2022]."},{"key":"e_1_3_4_9_2","unstructured":"Report of healthcare professionals in Italy 2020. Available from: www.pkegroup.it\/html\/blog\/infettivologi-in-italia-quanti-sono-e-dove-lavorano.asp [Last accessed: June 19 2021]."},{"key":"e_1_3_4_10_2","unstructured":"Italian Guidelines for the Use of Antiretroviral Agents. Edition 2017. Available from: www.salute.gov.it\/imgs\/C_17_pubblicazioni_2696_allegato.pdf [Last accessed: April 14 2022]."},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0254404"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-14-917"},{"key":"e_1_3_4_13_2","unstructured":"European AIDS Clinical Society. Treatment guidelines. 2021. Version 11.0. Available from: https:\/\/www.eacsociety.org\/guidelines\/eacs-guidelines\/eacs-guidelines.html [Last accessed: April 14 2022]."}],"container-title":["AIDS Research and Human Retroviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/aid.2022.0056","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2022.0056","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/aid.2022.0056","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:16:15Z","timestamp":1777367775000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/aid.2022.0056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1089\/aid.2022.0056"],"URL":"https:\/\/doi.org\/10.1089\/aid.2022.0056","relation":{},"ISSN":["0889-2229","1931-8405"],"issn-type":[{"value":"0889-2229","type":"print"},{"value":"1931-8405","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11]]}}}