{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:43:58Z","timestamp":1777380238040,"version":"3.51.4"},"reference-count":40,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:p>\n                    Public health surveillance data used in HIV molecular cluster analyses lack contextual information that is available from partner services (PS) data. Integrating these data sources in retrospective analyses can enrich understanding of the risk profile of people in clusters. In this study, HIV molecular clusters were identified and matched to information on partners and other information gleaned at the time of diagnosis, including coinfection with syphilis. We aimed to produce a more complete understanding of molecular cluster membership in Houston, Texas, a city ranking ninth nationally in rate of new HIV diagnoses that may benefit from retrospective matched analyses between molecular and PS data to inform future intervention. Data from PS were matched to molecular HIV records of people newly diagnosed from 2012 to 2018. By conducting analyses in HIV-TRACE (TRAnsmission Cluster Engine) using viral genetic sequences, molecular clusters were detected. Multivariable logistic regression models were used to estimate the association between molecular cluster membership and completion of a PS interview, number of named partners, and syphilis coinfection. Using data from 4,035 people who had a viral genetic sequence and matched PS records, molecular cluster membership was not significantly associated with completion of a PS interview. Among those with sequences who completed a PS interview (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20093,869), 45.3% (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20091,753) clustered. Molecular cluster membership was significantly associated with naming 1 or 3+ partners compared with not naming any partners [adjusted odds ratio, aOR: 1.27 (95% confidence interval, CI: 1.08\u20131.50),\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u2009.003 and aOR: 1.38 (95% CI: 1.06\u20131.81),\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u2009.02]. Alone, coinfection with syphilis was not significantly associated with molecular cluster membership. Syphilis coinfection was associated with molecular cluster membership when coupled with incarceration [aOR: 1.91 (95% CI: 1.08\u20133.38),\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u2009.03], a risk for treatment interruption. Enhanced intervention among those with similar profiles, such as people coinfected with other risks, may be warranted.\n                  <\/jats:p>","DOI":"10.1089\/aid.2022.0088","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T03:00:12Z","timestamp":1676343612000},"page":"241-252","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Predictors of HIV Molecular Cluster Membership and Implications for Partner Services"],"prefix":"10.1177","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6907-5658","authenticated-orcid":false,"given":"Camden J.","family":"Hallmark","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA."},{"name":"Houston Health Department, Houston, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Luswata","sequence":"additional","affiliation":[{"name":"Houston Health Department, Houston, Texas, USA."},{"name":"Department of Health Promotion and Behavioral Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natascha","family":"Del Vecchio","sequence":"additional","affiliation":[{"name":"Department of Medicine and Public Health Sciences and the Chicago Center for HIV Elimination, University of Chicago, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Hayford","sequence":"additional","affiliation":[{"name":"Third Coast Center for AIDS Research, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Mora","sequence":"additional","affiliation":[{"name":"Houston Health Department, Houston, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Carr","sequence":"additional","affiliation":[{"name":"Houston Health Department, Houston, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlene","family":"McNeese","sequence":"additional","affiliation":[{"name":"Houston Health Department, Houston, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanette","family":"Benbow","sequence":"additional","affiliation":[{"name":"Third Coast Center for AIDS Research, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Medicine and Public Health Sciences and the Chicago Center for HIV Elimination, University of Chicago, Chicago, Illinois, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel O.","family":"Wertheim","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California San Diego, La Jolla, California, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kayo","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Health Promotion and Behavioral Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,5,5]]},"reference":[{"key":"e_1_3_6_2_2","unstructured":"Centers for Disease Control and Prevention. HIV in the United States by Region; 2020. Available from: https:\/\/www.cdc.gov\/hiv\/statistics\/overview\/geographicdistribution.html [Last accessed: January 2 2021]."},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0016986"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006000"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001856"},{"key":"e_1_3_6_6_2","unstructured":"United States Census Bureau. QuickFacts: Houston City Texas. Population Estimates; July 1 2019. Available from: https:\/\/www.census.gov\/quickfacts\/houstoncitytexas [Last accessed: January 2 2021]."},{"key":"e_1_3_6_7_2","unstructured":"Centers for Disease Control and Prevention. HIV Surveillance Report 2019; 2021. 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Available from: https:\/\/texreg.sos.state.tx.us\/public\/readtac$sub.historicaltac?p_tac_id=174096 [Last accessed: September 24 2022]."},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.72.4.247"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2017-053288"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32831d2a81"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000003140"},{"key":"e_1_3_6_14_2","unstructured":"Centers for Disease Control and Prevention. Detecting and Responding to HIV Transmission Clusters: A Guide for Health Departments Draft Version 2.0; 2018. 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