{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:46:15Z","timestamp":1777380375751,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Research and Human Retroviruses"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n                    The unique recombinant form (URF) of HIV is formed by multiple subtypes which are cocirculating in some area, and the number of HIV recombinants is on the increase worldwide. In this study, we identified a URF named 2019638, composed of CRF01_AE and subtype B, in a man who has sex with men in Qinhuangdao, Hebei province, China. The near-full-length genome (NFLG) sequence was confirmed to be a novel URF. Within this NFLG, two CRF01_AE fragments were inserted into the\n                    <jats:italic toggle=\"yes\">pol<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">vif<\/jats:italic>\n                    regions, respectively, using subtype B as the backbone. Moreover, the presence of the V106M and V179D point mutations in the reverse transcriptase (RT) region rendered the high-level resistance to efavirenz and nevirapine and intermediate resistance to doravirine. Our findings suggest that the HIV epidemic is evolving toward a high degree of recombination, and we need to continuously monitor HIV genetic diversity to control the further development of the AIDS epidemic.\n                  <\/jats:p>","DOI":"10.1089\/aid.2023.0110","type":"journal-article","created":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T02:29:56Z","timestamp":1700447396000},"page":"257-262","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Near-Full-Length Genome Analysis of a HIV-1 CRF01_AE\/B Recombinant Strain Among Men Who Have Sex with Men in Chengde City, China"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3423-3529","authenticated-orcid":false,"given":"Shuofan","family":"Dong","sequence":"first","affiliation":[{"name":"Hebei Key Laboratory of Pathogen and Epidemiology of Infectious Disease, Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang, Hebei, China."},{"name":"School of Public Health, Hebei Medical University, Shijiazhuang, Hebei, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4613-2028","authenticated-orcid":false,"given":"Xinli","family":"Lu","sequence":"additional","affiliation":[{"name":"Hebei Key Laboratory of Pathogen and Epidemiology of Infectious Disease, Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang, Hebei, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingying","family":"Wang","sequence":"additional","affiliation":[{"name":"Hebei Key Laboratory of Pathogen and Epidemiology of Infectious Disease, Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang, Hebei, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"An","sequence":"additional","affiliation":[{"name":"Hebei Key Laboratory of Pathogen and Epidemiology of Infectious 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