{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T11:49:22Z","timestamp":1777549762153,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AIDS Patient Care and STDs"],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1089\/apc.2008.0012","type":"journal-article","created":{"date-parts":[[2008,9,18]],"date-time":"2008-09-18T11:05:44Z","timestamp":1221735944000},"page":"779-786","source":"Crossref","is-referenced-by-count":8,"title":["Metformin Increases HDL3\u2013Cholesterol and Decreases Subcutaneous Truncal Fat in Nondiabetic Patients with HIV-Associated Lipodystrophy"],"prefix":"10.1177","volume":"22","author":[{"given":"Leandro A.","family":"Diehl","sequence":"first","affiliation":[{"name":"State University of Londrina (UEL), Londrina, PR, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno A.","family":"Fabris","sequence":"additional","affiliation":[{"name":"State University of Londrina (UEL), Londrina, PR, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e9cio S","family":"Barbosa","sequence":"additional","affiliation":[{"name":"State University of Londrina (UEL), Londrina, PR, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliana C.","family":"De Faria","sequence":"additional","affiliation":[{"name":"State University of Campinas (UNICAMP), Campinas, SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susana L.","family":"Wiechmann","sequence":"additional","affiliation":[{"name":"State University of Londrina (UEL), Londrina, PR, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre J.F.","family":"Carrilho","sequence":"additional","affiliation":[{"name":"State University of Londrina (UEL), Londrina, PR, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"p_42","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041811"},{"key":"p_43","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200304001-00018"},{"key":"p_44","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2005.04.013"},{"key":"p_45","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.1.41"},{"key":"p_46","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-143-5-200509060-00009"},{"key":"p_47","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-140-10-200405180-00008"},{"key":"p_48","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-020709"},{"key":"p_49","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.20111"},{"key":"p_51","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1161\/circ.106.25.3143","volume":"106","author":"National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)","year":"2002","journal-title":"Circulation"},{"key":"p_52","first-page":"667","volume":"22","author":"Carr MC","year":"2002","journal-title":"Circulation"},{"key":"p_53","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-200512000-00007"},{"key":"p_54","doi-asserted-by":"publisher","DOI":"10.1021\/bi00794a019"},{"key":"p_55","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0022-2275(20)39891-6","volume":"36","author":"Syv\u00e4nne M","year":"1995","journal-title":"J Lipid Res"},{"key":"p_56","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2003.01263.x"},{"key":"p_57","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.52.2.453"},{"key":"p_58","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.6.1496"},{"key":"p_59","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2005.00273.x"},{"key":"p_60","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.104.3.257"},{"key":"p_61","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.20.12.2670"},{"key":"p_62","first-page":"1087","volume":"20","author":"Haffner SM","year":"1997","journal-title":"Diabetes"},{"key":"p_63","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.4.472"},{"key":"p_64","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328011220e"},{"key":"p_65","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2006.06.014"},{"key":"p_66","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2007.00488.x"},{"key":"p_67","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.6.1487"},{"key":"p_68","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.21.12.2191"},{"key":"p_69","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1161\/01.CIR.0000131512.50667.46","volume":"109","author":"Assmann G","year":"2004","journal-title":"Circulation"},{"key":"p_70","doi-asserted-by":"publisher","DOI":"10.1097\/00041433-199412000-00003"},{"key":"p_71","doi-asserted-by":"publisher","DOI":"10.1038\/ncpendmet0587"},{"key":"p_72","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0022-2275(20)31690-4","volume":"42","author":"Barlage S","year":"2001","journal-title":"J Lipid Res"},{"key":"p_73","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/S0022-2275(20)31621-7","volume":"42","author":"Khovidhunkig W","year":"2001","journal-title":"J Lipid Res"},{"key":"p_74","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2760(94)00240-Y"},{"key":"p_75","first-page":"1527","volume":"82","author":"Kwong LK","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"p_76","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/del003"},{"key":"p_77","first-page":"3389","volume":"82","author":"Rajkhowa M","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"p_78","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-1326.2002.00178.x"},{"key":"p_79","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199108083250601"},{"key":"p_80","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.84.1.129"},{"key":"p_81","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.2.769"},{"key":"p_82","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.17.6.1098"},{"key":"p_83","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000183727.90611.4f"},{"key":"p_84","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000091338.93223.E8"},{"key":"p_85","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-8981(99)00098-4"},{"key":"p_86","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118083"},{"key":"p_87","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.46.10.1579"},{"key":"p_88","doi-asserted-by":"publisher","DOI":"10.1210\/er.21.6.697"},{"key":"p_89","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-020794"},{"key":"p_90","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2006.0165"},{"key":"p_91","doi-asserted-by":"publisher","DOI":"10.1210\/jc.86.2.939"}],"container-title":["AIDS Patient Care and STDs"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/apc.2008.0012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:49:17Z","timestamp":1777398557000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/apc.2008.0012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10]]},"references-count":49,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["10.1089\/apc.2008.0012"],"URL":"https:\/\/doi.org\/10.1089\/apc.2008.0012","relation":{},"ISSN":["1087-2914","1557-7449"],"issn-type":[{"value":"1087-2914","type":"print"},{"value":"1557-7449","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10]]}}}