{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T21:25:56Z","timestamp":1785101156663,"version":"3.55.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T00:00:00Z","timestamp":1637798400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Patient Care and STDs"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:p>\n                    Little information is known about the cisgender women who seek and initiate pre-exposure prophylaxis (PrEP) for HIV prevention in the United States. Adherence Enhancement Guided by Individualized Texting and Drug Levels was a 48-week single-arm open-label demonstration study of daily oral tenofovir disoproxil fumaratel emtricitabine (TDF\/FTC) in cisgender women \u2265\u200918 years old at risk for HIV. Participants were surveyed at screening and enrollment about sociodemographics, HIV risk perception and behaviors, and PrEP perspectives and aggregated into three risk groups according to HIV sexual risk behavior: being in a serodiscordant partnership (SD), engaging in sex work (SW), and having partners with unknown HIV status at risk for HIV (UP). One hundred sixty-seven women presented for screening with\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200931 screen failures. Of the 162 women completing enrollment, mean age was 40 (standard deviation 11), with 41% non-Hispanic Black, 22% non-Hispanic White, and 19% Latina. Compared with those who screened ineligible, enrolled participants were more likely to have heard of PrEP, had higher HIV risk perception, and reported higher perceived PrEP efficacy. Sixty-four women (47%) were categorized as SD, 21 (15%) as SW, and 51 (38%) as UP. The SW were more likely to report higher levels of drinking and drug use (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u20090.002) and history of intimate partner violence in the past year (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.001) compared with SD and UP. Among cisgender women enrolled, there were significant differences between the three risk groups by demographics, HIV risk behavior, and PrEP perspectives, suggesting that interventions to successfully implement PrEP in US women may need to be tailored by HIV risk group.\n                  <\/jats:p>\n                  <jats:p>Clinical Trial Registration number: NCT02584140.<\/jats:p>","DOI":"10.1089\/apc.2021.0114","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T16:18:42Z","timestamp":1638375522000},"page":"481-487","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Pre-Exposure Prophylaxis Perspectives, Sociodemographic Characteristics, and HIV Risk Profiles of Cisgender Women Seeking and Initiating PrEP in a US Demonstration Project"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2307-9108","authenticated-orcid":false,"given":"Jill","family":"Blumenthal","sequence":"first","affiliation":[{"name":"Department of Medicine, University of California San Diego, San Diego, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael","family":"Landovitz","sequence":"additional","affiliation":[{"name":"Department of Medicine, Ronald Reagan UCLA Medical Center, University of California Los Angeles, Los Angeles, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Public Health, University of California San Diego, San Diego, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"He","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Public Health, University of California San Diego, San Diego, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Kofron","sequence":"additional","affiliation":[{"name":"Department of Medicine, Ronald Reagan UCLA Medical Center, University of California Los Angeles, Los Angeles, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Ellorin","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California San Diego, San Diego, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gifty M.","family":"Ntim","sequence":"additional","affiliation":[{"name":"Department of Medicine, Ronald Reagan UCLA Medical Center, University of California Los Angeles, Los Angeles, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamila K.","family":"Stockman","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California San Diego, San Diego, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katya","family":"Corado","sequence":"additional","affiliation":[{"name":"Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4458-6934","authenticated-orcid":false,"given":"K.","family":"Rivet Amico","sequence":"additional","affiliation":[{"name":"Department of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of California San Diego, San Diego, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheldon","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California San Diego, San Diego, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,11,25]]},"reference":[{"key":"e_1_3_5_2_2","unstructured":"HIV and Women: HIV Diagnoses. 2021. Available at: https:\/\/www.cdc.gov\/hiv\/group\/gender\/women\/diagnoses.html (Last accessed May25 2021)."},{"key":"e_1_3_5_3_2","unstructured":"Local Data: HIV in California. 2021. Available at: https:\/\/aidsvu.org\/local-data\/united-states\/west\/california\/#demographics-2018 (Last accessed May25 2021)."},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1108524"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70847-3"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1011205"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1110711"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00056-2"},{"key":"e_1_3_5_9_2","first-page":"364","article-title":"Vital signs: Estimated percentages and numbers of adults with indications for preexposure prophylaxis to prevent HIV acquisition\u2014United States, 2015","volume":"56","author":"Smith DK","year":"2015","unstructured":"Smith DK, , Van H, and el M, , Wolitski RJ, et al. Vital signs: Estimated percentages and numbers of adults with indications for preexposure prophylaxis to prevent HIV acquisition\u2014United States, 2015. J Mississippi State Med Assoc, 2015; 56:364\u2013371.","journal-title":"J Mississippi State Med Assoc"},{"key":"e_1_3_5_10_2","unstructured":"Bush S Magnuson D Rawlings K et al. Racial characteristics of FTC\/TDF for pre-exposure prophylaxis (PrEP) users in the US. Boston MA: ASM Microbe Conference 2016."},{"key":"e_1_3_5_11_2","unstructured":"Mera R McCallister S Mayer G Magnuson D Rawlings K. Truvada (TVD) for HIV pre-exposure prophylaxis (PrEP) utilization in the United States (2013\u20132015). 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