{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T04:07:53Z","timestamp":1787803673422,"version":"build-2784847793"},"reference-count":35,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Patient Care and STDs"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p>\n                    It remains unclear why patients discontinue HIV pre-exposure prophylaxis (PrEP) care and to what extent they remain at risk for HIV when they do. We reviewed routinely collected medical records and patient questionnaires and performed an e-mail\/telephone survey to assess reasons for discontinuing PrEP care, ongoing risks for HIV infection, and associated factors. Patients with more than two registered PrEP visits from a PrEP clinic in Antwerp, Belgium between June 2017 and February 2020 were included in this study. Patients who did not return for a visit after October 30, 2019 and who were not transferred out were considered as having discontinued PrEP care. A total of 143\/1073 patients were considered as having discontinued PrEP care. Patients who discontinued PrEP care were more likely to be younger than those who remained in care (35 vs. 38 years old,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.01). The most common reasons for discontinuation were having stopped using PrEP (62\/101, 61.4%) and \u201cCOVID-19\u201d (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200935, 34.7%). The most common reasons for stopping PrEP use was a decreased sexual activity due to coronavirus disease 2019 (COVID-19; 21\/62, 33.9%) or not COVID-19 related (10\/62, 16.1%), a monogamous relationship (20\/62, 32.3%) and consistent condom use (7\/62, 11.3%). Among respondents who reported about current HIV risk the majority reported being at low risk either by still taking PrEP (32\/91, 35.2%), consistently using condoms, or limiting number of sex acts or partners (58\/91, 52.7%). No HIV seroconversion was reported.\n                  <\/jats:p>","DOI":"10.1089\/apc.2021.0197","type":"journal-article","created":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T11:47:41Z","timestamp":1650368861000},"page":"159-167","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Why Do HIV Pre-Exposure Prophylaxis Users Discontinue Pre-Exposure Prophylaxis Care? A Mixed Methods Survey in a Pre-Exposure Prophylaxis Clinic in Belgium"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5541-6041","authenticated-orcid":false,"given":"Thibaut","family":"Vanbaelen","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences and Institute of Tropical Medicine, Antwerp, Belgium."},{"name":"Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anke","family":"Rotsaert","sequence":"additional","affiliation":[{"name":"Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart K.M.","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences and Institute of Tropical Medicine, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Florence","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences and Institute of Tropical Medicine, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Kenyon","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences and Institute of Tropical Medicine, Antwerp, Belgium."},{"name":"Division of Infectious Diseases and HIV Medicine, University of Cape Town, Cape Town, South Africa."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bea","family":"Vuylsteke","sequence":"additional","affiliation":[{"name":"Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Laga","sequence":"additional","affiliation":[{"name":"Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reyniers","family":"Thijs","sequence":"additional","affiliation":[{"name":"Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,4,14]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1506273"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00056-2"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1011205"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-018-2290-3"},{"key":"e_1_3_4_6_2","unstructured":"World Health Organization. Pre-Exposure Prophylaxis (PrEP). WHO Expands Recommendation on Oral PrEP of HIV Infection. 2015. Available at: apps.who.int\/iris\/bitstream\/10665\/197906\/1\/WHO_HIV_2015.48_eng.pdf?ua\u2009=\u20091 (Last accessed October1 2021)."},{"key":"e_1_3_4_7_2","unstructured":"Global PrEP Network. Global State of PrEP. 2021. Available at: https:\/\/www.who.int\/groups\/global-prep-network\/global-state-of-prep (Last accessed July1 2021)."},{"key":"e_1_3_4_8_2","unstructured":"AVAC. The Global PrEP Tracker. 2021. Available at: https:\/\/data.prepwatch.org\/"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002598"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001145"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz896"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-015-1238-0"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001385"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix593"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.25250"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-019-02493-w"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.25385"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.7448\/IAS.19.1.20903"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000002054"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-021-10174-4"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2020-054756"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2020-054598"},{"key":"e_1_3_4_23_2","unstructured":"Commission de remboursement des M\u00e9dicaments . M\u00e9dicament en PrEp pour pr\u00e9venir l'infection par le VIH: Remboursement au 1er juin 2017. 2017. Available at: https:\/\/www.inami.fgov.be\/fr\/themes\/cout-remboursement\/par-mutualite\/medicament-produits-sante\/remboursement\/specialites\/adaptations\/Pages\/medicament-PrEp-VIH.aspx (Last accessed November26 2020)."},{"key":"e_1_3_4_24_2","unstructured":"Sciensano. \u00c9pid\u00e9miologie Des Maladies Infectieuses \u00c9pid\u00e9miologie du Sida et de L'infection Au Vih En Belgique. 2019. Available at: https:\/\/www.sciensano.be\/en\/biblio\/epidemiologie-du-sida-et-de-linfection-a-vih-en-belgique-situation-au-31-decembre-2019 (Last accessed October1 2021)."},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-018-2045-1"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2019.0150"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001164"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.25389"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000823"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001888"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1097\/JNC.0000000000000137"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(21)00112-2"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2020-054688"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-03024-8"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2021.0075"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2021.0074"}],"container-title":["AIDS Patient Care and STDs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/apc.2021.0197","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/apc.2021.0197","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/apc.2021.0197","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:04:28Z","timestamp":1777399468000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/apc.2021.0197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1089\/apc.2021.0197"],"URL":"https:\/\/doi.org\/10.1089\/apc.2021.0197","relation":{},"ISSN":["1087-2914","1557-7449"],"issn-type":[{"value":"1087-2914","type":"print"},{"value":"1557-7449","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4]]}}}