{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T22:38:14Z","timestamp":1787870294757,"version":"build-2784847793"},"reference-count":38,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["AIDS Patient Care and STDs"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>\n                    Two hundred two people living with HIV (PLWH) selected from outpatients at the Infectious Disease Institute, Fondazione Policlinico Universitario A. Gemelli IRCCS, in Rome (Italy) were consecutively enrolled from May to July 2021. We used an anonymous telephone questionnaire to investigate opinions of PLWH about combined antiretroviral (ARV) therapy and long-acting (LA) formulations of ARVs. All invited participants completed the questionnaire (100%). We found that most PLWH evaluated taking HIV pills for the rest of their life as a continuous, but undemanding commitment (61.4%;\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009124), although they were willing to stop the daily intake of HIV drugs (78.2%,\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009158). Moreover, most PLWH were unaware of the existence of LA therapies at the time of the investigation (60.4%,\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009122). Almost half the PLWH evaluated the need for injections in the hospital as an obstacle (51.4%,\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009104). Regarding the preference between monthly injections and taking pills everyday, most PLWH (68.8%,\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009139) stated that the injection was more advantageous than pills even if they had some pain\/swelling at the injection site. The concern about LA therapy indicated most by PLWH was the possible lower efficacy of the drug (83.7%,\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009169). Regarding the possible benefits of LA therapy, those reported most by PLWH were feeling freer because they did not have to remember to take pills everyday (68,8%,\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009139). In conclusion, to date, PLWH in our cohort seem willing to accept LA therapy, but still show some concern about the efficacy of the new therapy and the obligation to come to the hospital to receive it. Thus, clinicians must take into account the needs of their patients and help them overcome their concerns to facilitate the transition to this new therapeutic modality.\n                  <\/jats:p>\n                  <jats:p>Clinical Trial Registration Number ID: 2424.<\/jats:p>","DOI":"10.1089\/apc.2022.0030","type":"journal-article","created":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T11:18:13Z","timestamp":1651663093000},"page":"178-185","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Use of Long-Acting Therapies for HIV Care in Italy: Are People Living with HIV Prepared for Change? A Cross-Sectional Study"],"prefix":"10.1177","volume":"36","author":[{"given":"Valentina","family":"Massaroni","sequence":"first","affiliation":[{"name":"Department of Safety and Bioethics, Infectious Diseases Institute, Catholic University of Sacred Heart, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0592-2747","authenticated-orcid":false,"given":"Valentina","family":"Delle Donne","sequence":"additional","affiliation":[{"name":"Department of Safety and Bioethics, Infectious Diseases Institute, Catholic University of Sacred Heart, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Borghetti","sequence":"additional","affiliation":[{"name":"UOC Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arturo","family":"Ciccullo","sequence":"additional","affiliation":[{"name":"UOC Infectious Diseases, Ospedale San Salvatore, L'Aquila, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Lombardi","sequence":"additional","affiliation":[{"name":"UOC Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Giuliano","sequence":"additional","affiliation":[{"name":"UOC Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damiano","family":"Farinacci","sequence":"additional","affiliation":[{"name":"UOC Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Visconti","sequence":"additional","affiliation":[{"name":"UOC Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrica","family":"Tamburrini","sequence":"additional","affiliation":[{"name":"UOC Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Di Giambenedetto","sequence":"additional","affiliation":[{"name":"Department of Safety and Bioethics, Infectious Diseases Institute, Catholic University of Sacred Heart, Rome, Italy."},{"name":"UOC Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,5,3]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200003303421303"},{"key":"e_1_3_5_3_2","first-page":"667","article-title":"Sexual activity without condoms and risk of HIV transmission in serodifferent couples when the HIV-positive partner is using suppressive antiretroviral therapy","volume":"316","author":"Rodger AJ","year":"2016","unstructured":"Rodger AJ, , Cambiano V, , Bruun T, et al. Sexual activity without condoms and risk of HIV transmission in serodifferent couples when the HIV-positive partner is using suppressive antiretroviral therapy. [published correction appears in JAMA, 2016; 316:667] [published correction appears in JAMA. 2016;316(19):2048]. 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In: National Library of Medicine: Abstracts of the XIII International AIDS Conference (Durban South Africa 2000). Available at: http:\/\/www.iac2000.org\/abdetail.asp?ID\u00bc WePeD4598"},{"key":"e_1_3_5_9_2","unstructured":"Wilson T Barren Y Cohen M et al. Prevalence and predictors of adherence to antiretroviral therapy (ART) among HIV\u00fe women [abstract TuPpD1199]. In: National Library of Medicine: Abstracts of the XIII International AIDS Conference (Durban South Africa 9\u201314 July 2000). Available at: http:\/\/www.iac2000.org\/abdetail.asp?ID\u00bcTuPpD1199."},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2020.0244"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2021.0096"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2020.0236"},{"key":"e_1_3_5_13_2","first-page":"75","article-title":"Long-acting agents for HIV infection: Biological aspects, role in treatment and prevention, and patient's perspective","volume":"40","author":"Rusconi S","year":"2017","unstructured":"Rusconi S, , Marcotullio S, , Cingolani A. Long-acting agents for HIV infection: Biological aspects, role in treatment and prevention, and patient's perspective. 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