{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T08:28:27Z","timestamp":1771230507725,"version":"3.50.1"},"reference-count":36,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1994,1,1]],"date-time":"1994-01-01T00:00:00Z","timestamp":757382400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antisense Research and Development"],"published-print":{"date-parts":[[1994,1]]},"DOI":"10.1089\/ard.1994.4.43","type":"journal-article","created":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T16:45:39Z","timestamp":1463503539000},"page":"43-52","source":"Crossref","is-referenced-by-count":76,"title":["Pharmacokinetics of an Antisense Phosphorothioate Oligodeoxynucleotide against\n                    <i>rev<\/i>\n                    from Human Immunodeficiency Virus Type 1 in the Adult Male Rat Following Single Injections and Continuous Infusion"],"prefix":"10.1177","volume":"4","author":[{"given":"PATRICK L.","family":"IVERSEN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOHN","family":"MATA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WILLIAM G.","family":"TRACEWELL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GERALD","family":"ZON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"p_82","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.17.7595"},{"key":"p_83","doi-asserted-by":"publisher","DOI":"10.1016\/0962-8924(92)90100-2"},{"key":"p_84","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1988.78"},{"key":"p_85","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-198308030-00002"},{"key":"p_86","doi-asserted-by":"publisher","DOI":"10.1089\/ard.1992.2.109"},{"key":"p_87","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(00)82193-3"},{"key":"p_88","first-page":"669","volume":"4","author":"BRODSKY I.","year":"1985","journal-title":"J. Biol. Resp. Modif."},{"key":"p_89","first-page":"815","volume":"18","author":"CHEM T.L.","year":"1990","journal-title":"Drug. Metab. Disp."},{"key":"p_90","first-page":"351","volume":"32","author":"CHIA D.","year":"1977","journal-title":"Immunology"},{"key":"p_91","first-page":"1","volume":"2","author":"CHIN DJ.","year":"1990","journal-title":"New Biol."},{"key":"p_92","first-page":"465","volume":"12","author":"CHUSED T.M.","year":"1972","journal-title":"Clin. Exp. Immunol."},{"key":"p_93","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-198917010-00001"},{"key":"p_94","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.54.070185.002055"},{"key":"p_95","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(86)90062-0"},{"key":"p_97","first-page":"877","volume":"25","author":"GOSSE C","year":"1965","journal-title":"Cancer Res."},{"key":"p_102","first-page":"2971","volume":"24","author":"INAGAKI M.","year":"1992","journal-title":"Transplant. Proc."},{"key":"p_103","first-page":"531","volume":"6","author":"IVERSEN P.","year":"1991","journal-title":"Anti-Cancer Drug Design"},{"key":"p_104","doi-asserted-by":"publisher","DOI":"10.1089\/ard.1992.2.211"},{"key":"p_105","doi-asserted-by":"publisher","DOI":"10.1016\/0169-409X(91)90019-9"},{"key":"p_106","doi-asserted-by":"publisher","DOI":"10.1126\/science.1299224"},{"key":"p_107","doi-asserted-by":"crossref","first-page":"24810","DOI":"10.1016\/S0021-9258(18)35836-8","volume":"267","author":"LESSER D.R.","year":"1992","journal-title":"J. Biol. Chem."},{"key":"p_108","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.23.11209"},{"key":"p_109","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.10.3474"},{"key":"p_110","doi-asserted-by":"crossref","first-page":"27039","DOI":"10.1089\/ard.1992.2.27","volume":"2","author":"MARTI G.","year":"1992","journal-title":"Antisense Res. Dev."},{"key":"p_111","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.11.4244"},{"key":"p_112","doi-asserted-by":"publisher","DOI":"10.1126\/science.1699273"},{"key":"p_113","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.24.11823"},{"key":"p_115","doi-asserted-by":"publisher","DOI":"10.3109\/03602538608998295"},{"key":"p_120","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/16.24.11691"},{"key":"p_121","doi-asserted-by":"publisher","DOI":"10.1021\/ja00332a054"},{"key":"p_122","first-page":"2659","volume":"48","author":"STEIN CA.","year":"1988","journal-title":"Cancer Res."},{"key":"p_124","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(90)90521-A"},{"key":"p_125","doi-asserted-by":"publisher","DOI":"10.1038\/1981088a0"},{"key":"p_126","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015846209681"},{"key":"p_127","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.17.6454"},{"key":"p_128","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015985728434"}],"container-title":["Antisense Research and Development"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/ard.1994.4.43","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T08:00:09Z","timestamp":1771228809000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/ard.1994.4.43"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,1]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1994,1]]}},"alternative-id":["10.1089\/ard.1994.4.43"],"URL":"https:\/\/doi.org\/10.1089\/ard.1994.4.43","relation":{},"ISSN":["1050-5261"],"issn-type":[{"value":"1050-5261","type":"print"}],"subject":[],"published":{"date-parts":[[1994,1]]}}}