{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T20:25:52Z","timestamp":1791059152202,"version":"4.1.0"},"reference-count":149,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antioxidants & Redox Signaling"],"published-print":{"date-parts":[[2020,8,1]]},"DOI":"10.1089\/ars.2020.8093","type":"journal-article","created":{"date-parts":[[2020,4,16]],"date-time":"2020-04-16T04:53:08Z","timestamp":1587012788000},"page":"247-262","source":"Crossref","is-referenced-by-count":68,"title":["Hypoxic-Ischemic Encephalopathy and Mitochondrial Dysfunction: Facts, Unknowns, and Challenges"],"prefix":"10.1177","volume":"33","author":[{"given":"Marianela","family":"Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Departamento de Bioqu\u00edmica and Centro de Investigaciones Biom\u00e9dicas (CEINBIO) and Facultad de Medicina, Hospital de Cl\u00ednicas, Universidad de la Rep\u00fablica, Montevideo, Uruguay."},{"name":"Departamento de Neonatolog\u00eda, Facultad de Medicina, Hospital de Cl\u00ednicas, Universidad de la Rep\u00fablica, Montevideo, Uruguay."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Valez","sequence":"additional","affiliation":[{"name":"Departamento de Bioqu\u00edmica and Centro de Investigaciones Biom\u00e9dicas (CEINBIO) and Facultad de Medicina, Hospital de Cl\u00ednicas, Universidad de la Rep\u00fablica, Montevideo, Uruguay."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Cimarra","sequence":"additional","affiliation":[{"name":"Departamento de Bioqu\u00edmica and Centro de Investigaciones Biom\u00e9dicas (CEINBIO) and Facultad de Medicina, Hospital de Cl\u00ednicas, Universidad de la Rep\u00fablica, Montevideo, Uruguay."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Blasina","sequence":"additional","affiliation":[{"name":"Departamento de Neonatolog\u00eda, Facultad de Medicina, Hospital de Cl\u00ednicas, Universidad de la Rep\u00fablica, Montevideo, Uruguay."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Radi","sequence":"additional","affiliation":[{"name":"Departamento de Bioqu\u00edmica and Centro de Investigaciones Biom\u00e9dicas (CEINBIO) and Facultad de Medicina, Hospital de Cl\u00ednicas, Universidad de la Rep\u00fablica, Montevideo, Uruguay."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-014-8954-8"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2019.02.025"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.11110213"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(02)02264-6"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198905000-00004"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-8-17"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038504"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0900854"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7172.1554"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.21.9.099801"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X18777928"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201300099"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.105197"},{"key":"B14","first-page":"317","volume":"16","author":"Berger R","year":"1991","journal-title":"J Dev Physiol"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/0736-5748(91)90015-E"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1007\/s40272-019-00373-3"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2015.08.007"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/BF02454148"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1980.tb04616.x"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(75)80928-8"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1042\/bj1280617"},{"key":"B22","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1542\/peds.75.2.217","volume":"75","author":"Brazy JE","year":"1985","journal-title":"Pediatrics"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2007.05.011"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/0065-2571(85)90049-4"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.08.023"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1996.0178"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5308-07.2008"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.3109\/10715762.2010.516254"},{"key":"B29","doi-asserted-by":"crossref","first-page":"29409","DOI":"10.1016\/S0021-9258(18)43894-X","volume":"269","author":"Castro L","year":"1994","journal-title":"J Biol Chem"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.31.18672"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.97677"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3212"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00310.2006"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2016.08.026"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.6b00045"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2007.01.034"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039273"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1975.tb11875.x"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1995.2895"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2004.06.003"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.1989.2"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(01)00306-1"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1097\/01.WCB.0000066287.21705.21"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2019.02.030"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00258"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-019-0587-1"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2005.11.011"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00568"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1021\/cb800279q"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041996"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2019.4011"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70058-3"},{"key":"B53","first-page":"392","volume":"4","author":"Franz JV.","year":"1999","journal-title":"Symp A Q J Mod Foreign Lit"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2018.03.008"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-8997-0_4"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1038\/nature07525"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199909000-00005"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119153"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.5.1098"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1159\/000069040"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2015.13"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70261-8"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.113.302131"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-306284"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1038\/nrn730"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2011.03.016"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2007.03.083"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.004816"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003311.pub3"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.65.092101.142558"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2004.05.020"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.06.040"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2009.05.004"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(97)01172-4"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.12.5675"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199512000-00015"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60496-7"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2013.206"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1159\/000467392"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(97)13349-3"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2010.01.034"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2017.04.027"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-018-1019-7"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1999.277.2.H799"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1007\/s12017-009-8058-1"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31593-8"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2008.01.003"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2014.05.021"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2018.09.010"},{"key":"B90","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2004.02565.x"},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-6147(03)00078-6"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.9b00150"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1821487116"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2019.02.006"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(94)00177-2"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4400353"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2017.66"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4048-05.2006"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.REV119.006136"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20081386"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2018.174"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7608108"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2427-x"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.20-02-00763.2000"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2007.06.060"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1203\/01.PDR.0000113546.03897.FC"},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X15617954"},{"key":"B108","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1996.0146"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-3806(00)00110-3"},{"key":"B110","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-3806(00)00111-5"},{"key":"B111","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2015.11.010"},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1804932115"},{"key":"B113","doi-asserted-by":"publisher","DOI":"10.1515\/BC.2002.044"},{"key":"B114","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1994.1013"},{"key":"B115","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410090206"},{"key":"B116","first-page":"5","author":"Rodriguez M","year":"2018","journal-title":"Medicina 3"},{"key":"B117","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1992.tb11432.x"},{"key":"B118","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2012.666398"},{"key":"B119","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2017.277"},{"key":"B120","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2015.05.078"},{"key":"B121","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R113.544635"},{"key":"B122","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-061516-045037"},{"key":"B123","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23081871"},{"key":"B124","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-3023-4_61"},{"key":"B125","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X18770331"},{"key":"B126","doi-asserted-by":"publisher","DOI":"10.1038\/nn1623"},{"key":"B127","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199909000-00007"},{"key":"B128","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199505000-00019"},{"key":"B129","doi-asserted-by":"publisher","DOI":"10.1002\/1873-3468.12943"},{"key":"B130","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.15.8756"},{"key":"B131","doi-asserted-by":"publisher","DOI":"10.1159\/000341715"},{"key":"B132","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2008.2060"},{"key":"B133","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4020-6051-9_5"},{"key":"B134","doi-asserted-by":"publisher","DOI":"10.1016\/bs.ai.2016.12.001"},{"key":"B135","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2003.049478"},{"key":"B136","first-page":"283","volume-title":"Principles of Free Radical Biomedicine","author":"Valez V","year":"2012"},{"key":"B137","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2012.10.012"},{"key":"B138","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-007-0629-2"},{"key":"B139","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.02.016"},{"key":"B140","doi-asserted-by":"publisher","DOI":"10.1097\/01.WCB.0000133250.03953.63"},{"key":"B141","doi-asserted-by":"publisher","DOI":"10.1159\/000085978"},{"key":"B142","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.01064"},{"key":"B143","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.08.034"},{"key":"B144","first-page":"156","volume":"72","author":"Volpe JJ.","year":"2012","journal-title":"Neurol"},{"key":"B145","doi-asserted-by":"publisher","DOI":"10.1002\/em.22021"},{"key":"B146","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.85"},{"key":"B147","doi-asserted-by":"publisher","DOI":"10.1016\/j.spen.2004.01.006"},{"key":"B148","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.520114"},{"key":"B149","doi-asserted-by":"publisher","DOI":"10.1126\/science.1219855"}],"container-title":["Antioxidants & Redox Signaling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/ars.2020.8093","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/ars.2020.8093","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:54:07Z","timestamp":1777377247000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/ars.2020.8093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,1]]},"references-count":149,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,8,1]]}},"alternative-id":["10.1089\/ars.2020.8093"],"URL":"https:\/\/doi.org\/10.1089\/ars.2020.8093","relation":{},"ISSN":["1523-0864","1557-7716"],"issn-type":[{"value":"1523-0864","type":"print"},{"value":"1557-7716","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,1]]}}}