{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:33:28Z","timestamp":1792179208244,"version":"4.4.0"},"reference-count":201,"publisher":"SAGE Publications","issue":"13-15","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Antioxidants &amp; Redox Signaling"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec>\n                    <jats:title>Significance:<\/jats:title>\n                    <jats:p>\n                      Hydrogen sulfide (H\n                      <jats:sub>2<\/jats:sub>\n                      S) is considered to be a gasotransmitter along with carbon monoxide (CO) and nitric oxide (NO), and is known as a key regulator of physiological and pathological activities. S-sulfhydration (also known as persulfidation), a mechanism involving the formation of protein persulfides by modification of cysteine residues, is proposed here to explain the multiple biological functions of H\n                      <jats:sub>2<\/jats:sub>\n                      S. Investigating the properties of protein persulfides can provide a foundation for further understanding of the potential functions of H\n                      <jats:sub>2<\/jats:sub>\n                      S.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Recent Advances:<\/jats:title>\n                    <jats:p>Multiple methods have been developed to determine the level of protein persulfides. It has been demonstrated that protein persulfidation is involved in many biological processes through various mechanisms including the regulation of ion channels, enzymes, and transcription factors, as well as influencing protein\u2013protein interactions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Critical Issues:<\/jats:title>\n                    <jats:p>Some technical and theoretical questions remain to be solved. These include how to improve the specificity of the detection methods for protein persulfidation, why persulfidation typically occurs on one or a few thiols within a protein, how this modification alters protein functions, and whether protein persulfidation has organ-specific patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Future Directions:<\/jats:title>\n                    <jats:p>\n                      Optimizing the detection methods and elucidating the properties and molecular functions of protein persulfidation would be beneficial for current therapeutics. In this review, we introduce the detailed mechanism of the persulfidation process and discuss persulfidation detection methods. In addition, this review summarizes recent discoveries of the selectivity of protein persulfidation and the regulation of protein functions and cell signaling pathways by persulfidation.\n                      <jats:italic toggle=\"yes\">Antioxid. Redox Signal.<\/jats:italic>\n                      39, 829\u2013852.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/ars.2022.0064","type":"journal-article","created":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T11:29:34Z","timestamp":1679398174000},"page":"829-852","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":49,"title":["Protein Persulfidation: Recent Progress and Future Directions"],"prefix":"10.1177","volume":"39","author":[{"given":"Shanshan","family":"Luo","sequence":"first","affiliation":[{"name":"Key Laboratory of Cardiovascular and Cerebrovascular Medicine, Nanjing Medical University, Nanjing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuiyu","family":"Kong","sequence":"additional","affiliation":[{"name":"Key Laboratory of Cardiovascular and Cerebrovascular Medicine, Nanjing Medical University, Nanjing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danyu","family":"Ye","sequence":"additional","affiliation":[{"name":"Key Laboratory of Cardiovascular and Cerebrovascular Medicine, Nanjing Medical University, Nanjing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Targeted Intervention of Cardiovascular Disease, Nanjing Medical University, Nanjing, China."},{"name":"Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Cardiovascular and Cerebrovascular Medicine, Nanjing Medical University, Nanjing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoliang","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, First Affiliated Hospital of Nanjing Medical University, Nanjing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Xie","sequence":"additional","affiliation":[{"name":"Key Laboratory of Targeted Intervention of Cardiovascular Disease, Nanjing Medical University, Nanjing, China."},{"name":"Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, China."},{"name":"The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Nanjing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2650-5747","authenticated-orcid":false,"given":"Yong","family":"Ji","sequence":"additional","affiliation":[{"name":"Key Laboratory of Cardiovascular and Cerebrovascular Medicine, Nanjing Medical University, Nanjing, China."},{"name":"Key Laboratory of Targeted Intervention of Cardiovascular Disease, Nanjing Medical University, Nanjing, China."},{"name":"Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, China."},{"name":"The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Nanjing, China."},{"name":"National Key Laboratory of Frigid Zone Cardiovascular Diseases (NKLFZCD), Harbin Medical University, Harbin, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,11,13]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.16-03-01066.1996"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01311-y"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-018-0116-2"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1711.2005.01387.x"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2005478"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.6b01093"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.60.1.667"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2020.129560"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2017.09.008"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-18144-8_8"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2019.101379"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.051877"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1124\/mol.117.109645"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCO.0000000000000526"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-009-0445-2"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2020.8049"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14394"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA119.012357"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1006\/prep.1994.1063"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2016.03.001"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI73780"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2001.4448"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M805287200"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0194176"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.REV118.005604"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1093891"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2013.12.031"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.107.156059"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.6153-11.2012"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2016.02.028"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.672816"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.045344"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2019.172455"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-87646-5"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.105119"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abe7006"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aax8358"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1500968"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2017.7195"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.517995"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201489729"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0609307104"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2690335"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14719"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abb6477"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-050511-102321"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.699850"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja3009693"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00205"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.90566.2008"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1124\/mol.112.081596"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.10067"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409854102"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2017225118"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2012.5041"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2014.01.009"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA117.001679"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1268"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00021.2009"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.11.048"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0004(03)00057-4"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1997.6878"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/2807490"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1321232111"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2017.03.027"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2021.1876342"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-2952(99)00060-x"},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.8b02592"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00506.2012"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2011.224212"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2015.09.007"},{"key":"e_1_3_4_73_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2021.0029"},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.16423"},{"key":"e_1_3_4_75_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.5b01132"},{"key":"e_1_3_4_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2015.08.003"},{"key":"e_1_3_4_77_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00281.2014"},{"key":"e_1_3_4_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470720134.ch11"},{"key":"e_1_3_4_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14579"},{"key":"e_1_3_4_80_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom11060896"},{"key":"e_1_3_4_81_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.12-226415"},{"key":"e_1_3_4_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2017.08.017"},{"key":"e_1_3_4_83_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1989.01070010243030"},{"key":"e_1_3_4_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(10)73003-2"},{"key":"e_1_3_4_85_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.120.314084"},{"key":"e_1_3_4_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2016.09.012"},{"key":"e_1_3_4_87_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan4665"},{"key":"e_1_3_4_88_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1995.0592"},{"key":"e_1_3_4_89_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2002329"},{"key":"e_1_3_4_90_1","doi-asserted-by":"publisher","DOI":"10.2174\/1871527317666180605072018"},{"key":"e_1_3_4_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2005.10.001"},{"key":"e_1_3_4_92_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.25.15366"},{"key":"e_1_3_4_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2019.101179"},{"key":"e_1_3_4_94_1","doi-asserted-by":"publisher","DOI":"10.1080\/15384101.2020.1804179"},{"key":"e_1_3_4_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2021.102111"},{"key":"e_1_3_4_96_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2016.6936"},{"key":"e_1_3_4_97_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.12585"},{"key":"e_1_3_4_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2018.05.023"},{"key":"e_1_3_4_99_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12451"},{"key":"e_1_3_4_100_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14330"},{"key":"e_1_3_4_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2014.03.005"},{"key":"e_1_3_4_102_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2011.4005"},{"key":"e_1_3_4_103_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/6325378"},{"key":"e_1_3_4_104_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb3763"},{"key":"e_1_3_4_105_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep29808"},{"key":"e_1_3_4_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2013.05.020"},{"key":"e_1_3_4_107_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.15587"},{"key":"e_1_3_4_108_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja211931f"},{"key":"e_1_3_4_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2020.12.440"},{"key":"e_1_3_4_110_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.9b01978"},{"key":"e_1_3_4_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2022.102387"},{"key":"e_1_3_4_112_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.15.3910"},{"key":"e_1_3_4_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)77815-6"},{"key":"e_1_3_4_114_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.004160"},{"key":"e_1_3_4_115_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13825"},{"key":"e_1_3_4_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2014.10.019"},{"key":"e_1_3_4_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2016.08.023"},{"key":"e_1_3_4_118_1","doi-asserted-by":"publisher","DOI":"10.4161\/chan.3.1.7655"},{"key":"e_1_3_4_119_1","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio779"},{"key":"e_1_3_4_120_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2000464"},{"key":"e_1_3_4_121_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.240242"},{"key":"e_1_3_4_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2018.01.056"},{"key":"e_1_3_4_123_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-18144-8_10"},{"key":"e_1_3_4_124_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2020.8077"},{"key":"e_1_3_4_125_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00465.2016"},{"key":"e_1_3_4_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.11.066"},{"key":"e_1_3_4_127_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2020.8132"},{"key":"e_1_3_4_128_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1317320111"},{"key":"e_1_3_4_129_1","doi-asserted-by":"publisher","DOI":"10.1021\/cb4001052"},{"key":"e_1_3_4_130_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9112470"},{"key":"e_1_3_4_131_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6686"},{"key":"e_1_3_4_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3391"},{"key":"e_1_3_4_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2015.08.007"},{"key":"e_1_3_4_134_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr300163e"},{"key":"e_1_3_4_135_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.24.17075"},{"key":"e_1_3_4_136_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi1008694"},{"key":"e_1_3_4_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/352711a0"},{"key":"e_1_3_4_138_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.15-278648"},{"key":"e_1_3_4_139_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1313247110"},{"key":"e_1_3_4_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01680"},{"key":"e_1_3_4_141_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2011.02329.x"},{"key":"e_1_3_4_142_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom10091245"},{"key":"e_1_3_4_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2011.10.021"},{"key":"e_1_3_4_144_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1916895117"},{"key":"e_1_3_4_145_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201007175"},{"key":"e_1_3_4_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2021.119803"},{"key":"e_1_3_4_147_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.9b00562"},{"key":"e_1_3_4_148_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2371"},{"key":"e_1_3_4_149_1","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/mvp111"},{"key":"e_1_3_4_150_1","doi-asserted-by":"publisher","DOI":"10.1530\/JOE-20-0190"},{"key":"e_1_3_4_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2017.12.009"},{"key":"e_1_3_4_152_1","doi-asserted-by":"publisher","DOI":"10.1038\/nsb0498-247"},{"key":"e_1_3_4_153_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2060267"},{"key":"e_1_3_4_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2018.10.031"},{"key":"e_1_3_4_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2013.04.002"},{"key":"e_1_3_4_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2020.101813"},{"key":"e_1_3_4_157_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14601"},{"key":"e_1_3_4_158_1","doi-asserted-by":"publisher","DOI":"10.14336\/AD.2019.0524"},{"key":"e_1_3_4_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2009.08.008"},{"key":"e_1_3_4_160_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2012.5033"},{"key":"e_1_3_4_161_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules190812789"},{"key":"e_1_3_4_162_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2017.03.025"},{"key":"e_1_3_4_163_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01681"},{"key":"e_1_3_4_164_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2623"},{"key":"e_1_3_4_165_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2011.4310"},{"key":"e_1_3_4_166_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2018.02.011"},{"key":"e_1_3_4_167_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/8877691"},{"key":"e_1_3_4_168_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0211hyp"},{"key":"e_1_3_4_169_1","doi-asserted-by":"publisher","DOI":"10.1089\/152308603768295249"},{"key":"e_1_3_4_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2004.06.007"},{"key":"e_1_3_4_171_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201845986"},{"key":"e_1_3_4_172_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.niox.2014.06.003"},{"key":"e_1_3_4_173_1","doi-asserted-by":"publisher","DOI":"10.1039\/c5sc04818d"},{"key":"e_1_3_4_174_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09472"},{"key":"e_1_3_4_175_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-082411-113907"},{"key":"e_1_3_4_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2018.08.008"},{"key":"e_1_3_4_177_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2013.06.013"},{"key":"e_1_3_4_178_1","doi-asserted-by":"publisher","DOI":"10.2337\/db16-0020"},{"key":"e_1_3_4_179_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2013.5604"},{"key":"e_1_3_4_180_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M117.778654"},{"key":"e_1_3_4_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2017.11.008"},{"key":"e_1_3_4_182_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1162667"},{"key":"e_1_3_4_183_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2012.4645"},{"key":"e_1_3_4_184_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-018-2233-x"},{"key":"e_1_3_4_185_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.07.017"},{"key":"e_1_3_4_186_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0404161101"},{"key":"e_1_3_4_187_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2019.7728"},{"key":"e_1_3_4_188_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.08.003"},{"key":"e_1_3_4_189_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00608"},{"key":"e_1_3_4_190_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201305876"},{"key":"e_1_3_4_191_1","doi-asserted-by":"publisher","DOI":"10.1042\/CS20190514"},{"key":"e_1_3_4_192_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00882"},{"key":"e_1_3_4_193_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2019.04.063"},{"key":"e_1_3_4_194_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202002675R"},{"key":"e_1_3_4_195_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.559518"},{"key":"e_1_3_4_196_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31247"},{"key":"e_1_3_4_197_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.279.5357.1718"},{"key":"e_1_3_4_198_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2016.6826"},{"key":"e_1_3_4_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2017.01.026"},{"key":"e_1_3_4_200_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2005.12.030"},{"key":"e_1_3_4_201_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20174202"},{"key":"e_1_3_4_202_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2019.10.007"}],"container-title":["Antioxidants &amp; Redox Signaling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/ars.2022.0064","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/ars.2022.0064","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/ars.2022.0064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:55:26Z","timestamp":1777377326000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/ars.2022.0064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":201,"journal-issue":{"issue":"13-15","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1089\/ars.2022.0064"],"URL":"https:\/\/doi.org\/10.1089\/ars.2022.0064","relation":{},"ISSN":["1523-0864","1557-7716"],"issn-type":[{"value":"1523-0864","type":"print"},{"value":"1557-7716","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11]]}}}