{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T05:20:18Z","timestamp":1794201618552,"version":"4.8.0"},"reference-count":301,"publisher":"SAGE Publications","issue":"16-18","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Antioxidants &amp; Redox Signaling"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n                    <jats:title>Significance:<\/jats:title>\n                    <jats:p>Lipids, which constitute the highest portion (over 50%) of brain dry mass, are crucial for brain integrity, energy homeostasis, and signaling regulation. Emerging evidence revealed that lipid profile alterations and abnormal lipid metabolism occur during normal aging and in different forms of neurodegenerative diseases. Moreover, increasing genome-wide association studies have validated new targets on lipid-associated pathways involved in disease development. Myelin, the protective sheath surrounding axons, is crucial for efficient neural signaling transduction. As the primary site enriched with lipids, impairments of myelin are increasingly recognized as playing significant and complex roles in various neurodegenerative diseases, beyond simply being secondary effects of neuronal loss.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Recent Advances:<\/jats:title>\n                    <jats:p>With advances in the lipidomics field, myelin lipid alterations and their roles in contributing to or reflecting the progression of diseases, including Alzheimer\u2019s disease, Parkinson\u2019s disease, Huntington\u2019s disease, amyotrophic lateral sclerosis, multiple sclerosis, and others, have recently caught great attention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Critical Issues:<\/jats:title>\n                    <jats:p>This review summarizes recent findings of myelin lipid alterations in the five most common neurodegenerative diseases and discusses their implications in disease pathogenesis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Future Directions:<\/jats:title>\n                    <jats:p>\n                      By highlighting myelin lipid abnormalities in neurodegenerative diseases, this review aims to encourage further research focused on lipids and the development of new lipid-oriented therapeutic approaches in this area.\n                      <jats:italic toggle=\"yes\">Antioxid. Redox Signal.<\/jats:italic>\n                      00, 000\u2013000.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/ars.2024.0676","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T06:35:00Z","timestamp":1732257300000},"page":"1073-1099","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":26,"title":["Myelin Lipid Alterations in Neurodegenerative Diseases: Landscape and Pathogenic Implications"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3725-7726","authenticated-orcid":false,"given":"Ziying","family":"Xu","sequence":"first","affiliation":[{"name":"Sam and Ann Barshop Institute for Longevity and Aging Studies, UT Health San Antonio, San Antonio, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sijia","family":"He","sequence":"additional","affiliation":[{"name":"Sam and Ann Barshop Institute for Longevity and Aging Studies, UT Health San Antonio, San Antonio, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mst Marium","family":"Begum","sequence":"additional","affiliation":[{"name":"Sam and Ann Barshop Institute for Longevity and Aging Studies, UT Health San Antonio, San Antonio, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianlin","family":"Han","sequence":"additional","affiliation":[{"name":"Sam and Ann Barshop Institute for Longevity and Aging Studies, UT Health San Antonio, San Antonio, Texas, USA."},{"name":"Department of Medicine, UT Health San Antonio, San Antonio, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,12,10]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.13016"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon.12679"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1996.tb00182.x"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.10101284"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nurt.2007.05.011"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2022.577935"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201707763"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-72654-8"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-014-7425-5"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-92112-3"},{"issue":"11","key":"e_1_3_5_12_1","first-page":"105323","article-title":"Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry","volume":"25","author":"Arends M","year":"2022","unstructured":"Arends M, , Weber M, , Papan C, et al. Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry. Science, 2022; 25(11):105323.","journal-title":"Science"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21117"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-023-02170-4"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/00207454.2014.996640"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-32-9636-7_11"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13041-023-01055-5"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.47.4.300"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612822666151204000636"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/920958"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2008.10.011"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.26.11.1011"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0103727"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.3.393"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-007-9352-7"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/21678421.2013.865749"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp406"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemphyslip.2018.08.003"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI28873"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-023-00790-6"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05439-w"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-17389-9"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1991.00530220048018"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2017.05.023"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.00883"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b04227"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2008.02503.x"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.31083\/j.fbl2712331"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-015-0271-6"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon.12945"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/WAD.0b013e318032d2b1"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.16-13-04069.1996"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2001.tb00159.x"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-191683"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0172348"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0074-7742(07)79026-8"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-48059-7"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458514561908"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017299"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.12368"},{"issue":"5","key":"e_1_3_5_51_1","first-page":"809","article-title":"Specificity and potential mechanism of sulfatide deficiency in Alzheimer\u2019s disease: An electrospray ionization mass spectrometric study","volume":"49","author":"Cheng H","year":"2003","unstructured":"Cheng H, , Xu J, , Mckeel DW, et al. Specificity and potential mechanism of sulfatide deficiency in Alzheimer\u2019s disease: An electrospray ionization mass spectrometric study. Cell Mol Biol (Noisy-le-Grand), 2003; 49(5):809\u2013818.","journal-title":"Cell Mol Biol (Noisy-le-Grand)"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2008.07.020"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)43121-9"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-018-9863-7"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R009761"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl100"},{"issue":"2","key":"e_1_3_5_57_1","first-page":"59","article-title":"Jean-Martin Charcot. 1825 to 1893","volume":"15","author":"Clanet M","year":"2008","unstructured":"Clanet M. Jean-Martin Charcot. 1825 to 1893. Int MS J, 2008; 15(2):59\u201361.","journal-title":"Int MS J"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80093-8"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08220-X"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61620-7"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2016.03.027"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-171054"},{"key":"e_1_3_5_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-018-0206-4"},{"key":"e_1_3_5_64_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0305799101"},{"key":"e_1_3_5_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10312"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222111330"},{"key":"e_1_3_5_67_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2016.3232"},{"key":"e_1_3_5_68_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2128"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00495383"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2010.06964.x"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20734"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2007.05.003"},{"key":"e_1_3_5_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-05709-y"},{"key":"e_1_3_5_74_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2017.00698"},{"key":"e_1_3_5_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-010-4259-6"},{"key":"e_1_3_5_76_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1508767112"},{"key":"e_1_3_5_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5805-z"},{"key":"e_1_3_5_78_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000285080.70324.27"},{"key":"e_1_3_5_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.24423"},{"key":"e_1_3_5_80_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-008-8022-3"},{"key":"e_1_3_5_81_1","doi-asserted-by":"publisher","DOI":"10.2174\/1567205011310020004"},{"key":"e_1_3_5_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-019-0103-7"},{"key":"e_1_3_5_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(90)90199-W"},{"key":"e_1_3_5_84_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1607496113"},{"key":"e_1_3_5_85_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1997.69052064.x"},{"key":"e_1_3_5_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2020.108672"},{"key":"e_1_3_5_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00393-2"},{"key":"e_1_3_5_88_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.653842"},{"key":"e_1_3_5_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2003.10.004"},{"key":"e_1_3_5_90_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23095202"},{"key":"e_1_3_5_91_1","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/10.1.39"},{"key":"e_1_3_5_92_1","doi-asserted-by":"publisher","DOI":"10.2174\/1567205014666170117094038"},{"key":"e_1_3_5_93_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep31652"},{"key":"e_1_3_5_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12410"},{"key":"e_1_3_5_95_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-6741-1_1"},{"key":"e_1_3_5_96_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26278"},{"key":"e_1_3_5_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2012.10.001"},{"key":"e_1_3_5_98_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4366-05.2006"},{"key":"e_1_3_5_99_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222212256"},{"key":"e_1_3_5_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2017.05.009"},{"key":"e_1_3_5_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(21)00414-2"},{"key":"e_1_3_5_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61522-6"},{"key":"e_1_3_5_103_1","doi-asserted-by":"publisher","DOI":"10.3233\/JHD-150173"},{"key":"e_1_3_5_104_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.585703"},{"key":"e_1_3_5_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2017.08.026"},{"key":"e_1_3_5_106_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24119558"},{"key":"e_1_3_5_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(90)91154-9"},{"key":"e_1_3_5_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2005.10.018"},{"key":"e_1_3_5_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2014.10.010"},{"key":"e_1_3_5_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(89)90373-9"},{"key":"e_1_3_5_111_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-006-9145-4"},{"key":"e_1_3_5_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2018.02.028"},{"issue":"9","key":"e_1_3_5_113_1","first-page":"1950","article-title":"Immunological role of sulfatide in the pathogenesis of multiple sclerosis","volume":"18","author":"Hamatani M","year":"2023","unstructured":"Hamatani M, , Kondo T. Immunological role of sulfatide in the pathogenesis of multiple sclerosis. Neural Regen Res, 2023; 18(9):1950\u20131951.","journal-title":"Neural Regen Res"},{"key":"e_1_3_5_114_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-022-02881-9"},{"key":"e_1_3_5_115_1","doi-asserted-by":"publisher","DOI":"10.2174\/1567205052772786"},{"key":"e_1_3_5_116_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2007.04708.x"},{"key":"e_1_3_5_117_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-009-8092-x"},{"key":"e_1_3_5_118_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M212340200"},{"key":"e_1_3_5_119_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R300004-JLR200"},{"key":"e_1_3_5_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jlr.2021.100164"},{"key":"e_1_3_5_121_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2001.00332.x"},{"key":"e_1_3_5_122_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2002.00997.x"},{"key":"e_1_3_5_123_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2017.107"},{"key":"e_1_3_5_124_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.71"},{"key":"e_1_3_5_125_1","doi-asserted-by":"publisher","DOI":"10.20900\/immunometab20200019"},{"key":"e_1_3_5_126_1","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.1332"},{"key":"e_1_3_5_127_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20110566"},{"key":"e_1_3_5_128_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-05313-0"},{"key":"e_1_3_5_129_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.103935"},{"key":"e_1_3_5_130_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2018.00206"},{"key":"e_1_3_5_131_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-016-0354-z"},{"key":"e_1_3_5_132_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-018-4614-2"},{"key":"e_1_3_5_133_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M057869"},{"key":"e_1_3_5_134_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.032068299"},{"key":"e_1_3_5_135_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl290"},{"key":"e_1_3_5_136_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.14468"},{"key":"e_1_3_5_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(03)00131-0"},{"key":"e_1_3_5_138_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.13856"},{"key":"e_1_3_5_139_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-15-06507.2002"},{"key":"e_1_3_5_140_1","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00016.2009"},{"key":"e_1_3_5_141_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac050276v"},{"key":"e_1_3_5_142_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.11.8077"},{"key":"e_1_3_5_143_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-019-0138-8"},{"key":"e_1_3_5_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dadm.2016.03.001"},{"key":"e_1_3_5_145_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3357"},{"key":"e_1_3_5_146_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410360213"},{"key":"e_1_3_5_147_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.9b00532"},{"key":"e_1_3_5_148_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.14999"},{"key":"e_1_3_5_149_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-023-00558-1"},{"key":"e_1_3_5_150_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1700465115"},{"key":"e_1_3_5_151_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-017-0015-3"},{"key":"e_1_3_5_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2014.02.010"},{"key":"e_1_3_5_153_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0125339"},{"key":"e_1_3_5_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/0197-0186(92)90058-Y"},{"issue":"3","key":"e_1_3_5_155_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1387\/ijdb.1814411","article-title":"Human brain gangliosides in development, aging and disease","volume":"35","author":"Kracun I","year":"1991","unstructured":"Kracun I, , Rosner H, , Drnovsek V, et al. Human brain gangliosides in development, aging and disease. Int J Dev Biol, 1991; 35(3):289\u2013295.","journal-title":"Int J Dev Biol"},{"key":"e_1_3_5_156_1","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1999.7190"},{"key":"e_1_3_5_157_1","doi-asserted-by":"publisher","DOI":"10.3233\/JHD-160205"},{"key":"e_1_3_5_158_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mt.6300012"},{"key":"e_1_3_5_159_1","doi-asserted-by":"publisher","DOI":"10.1080\/00207450390162263"},{"key":"e_1_3_5_160_1","doi-asserted-by":"publisher","DOI":"10.1042\/CS20180506"},{"key":"e_1_3_5_161_1","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwj122"},{"key":"e_1_3_5_162_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-7844-0_16"},{"key":"e_1_3_5_163_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00308949"},{"key":"e_1_3_5_164_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2017.138"},{"key":"e_1_3_5_165_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1702-08.2008"},{"key":"e_1_3_5_166_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-1981(99)00201-2"},{"key":"e_1_3_5_167_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2005.03.025"},{"key":"e_1_3_5_168_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20292"},{"key":"e_1_3_5_169_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-023-01544-7"},{"key":"e_1_3_5_170_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.10-168633"},{"key":"e_1_3_5_171_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-011-4802-0"},{"key":"e_1_3_5_172_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M051839"},{"key":"e_1_3_5_173_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1994.tb01656.x"},{"key":"e_1_3_5_174_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi061749a"},{"key":"e_1_3_5_175_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A0605"},{"key":"e_1_3_5_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.06.001"},{"key":"e_1_3_5_177_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.26858"},{"key":"e_1_3_5_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2005.03.023"},{"key":"e_1_3_5_179_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073094"},{"key":"e_1_3_5_180_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(05)70071-5"},{"key":"e_1_3_5_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2009.11.010"},{"key":"e_1_3_5_182_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(02)00207-1"},{"key":"e_1_3_5_183_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-010-0657-2"},{"key":"e_1_3_5_184_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-99979-2"},{"key":"e_1_3_5_185_1","doi-asserted-by":"crossref","first-page":"e072529","DOI":"10.1136\/bmj-2022-072529","article-title":"Long covid outcomes at one year after mild SARS-CoV-2 infection: Nationwide cohort study","volume":"380","author":"Mizrahi B","year":"2023","unstructured":"Mizrahi B, , Sudry T, , Flaks-Manov N, et al. Long covid outcomes at one year after mild SARS-CoV-2 infection: Nationwide cohort study. BMJ, 2023; 380:e072529.","journal-title":"BMJ"},{"key":"e_1_3_5_186_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2004.02849.x"},{"key":"e_1_3_5_187_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2014.04.012"},{"key":"e_1_3_5_188_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-011-8287-6"},{"key":"e_1_3_5_189_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10719-012-9454-6"},{"key":"e_1_3_5_190_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.14789"},{"key":"e_1_3_5_191_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458511405561"},{"key":"e_1_3_5_192_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn146"},{"key":"e_1_3_5_193_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp044"},{"key":"e_1_3_5_194_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-47906-x"},{"key":"e_1_3_5_195_1","doi-asserted-by":"publisher","DOI":"10.2217\/nmt.14.21"},{"key":"e_1_3_5_196_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1973.tb07520.x"},{"key":"e_1_3_5_197_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2013.11.009"},{"key":"e_1_3_5_198_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22756"},{"key":"e_1_3_5_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2015.11.010"},{"key":"e_1_3_5_200_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2017.03.011"},{"key":"e_1_3_5_201_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.137286"},{"key":"e_1_3_5_202_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24010233"},{"key":"e_1_3_5_203_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.13738"},{"key":"e_1_3_5_204_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/408681"},{"key":"e_1_3_5_205_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2009.06150.x"},{"key":"e_1_3_5_206_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440518"},{"key":"e_1_3_5_207_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.14.7.913"},{"key":"e_1_3_5_208_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2022.09.004"},{"key":"e_1_3_5_209_1","doi-asserted-by":"publisher","DOI":"10.1159\/000338181"},{"key":"e_1_3_5_210_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2014.05.015"},{"key":"e_1_3_5_211_1","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcab303"},{"key":"e_1_3_5_212_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073280"},{"key":"e_1_3_5_213_1","doi-asserted-by":"publisher","DOI":"10.2217\/clp.11.8"},{"key":"e_1_3_5_214_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9040812"},{"key":"e_1_3_5_215_1","doi-asserted-by":"publisher","DOI":"10.3233\/RNN-1998-00046"},{"key":"e_1_3_5_216_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0203057"},{"key":"e_1_3_5_217_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo10090366"},{"key":"e_1_3_5_218_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-012-6420-y"},{"key":"e_1_3_5_219_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13041-017-0340-9"},{"key":"e_1_3_5_220_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.076810"},{"key":"e_1_3_5_221_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241310483"},{"key":"e_1_3_5_222_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.343893"},{"key":"e_1_3_5_223_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-021-00488-7"},{"issue":"2","key":"e_1_3_5_224_1","first-page":"87","article-title":"White matter injury in amyotrophic lateral sclerosis (ALS)","volume":"34","author":"Rafa\u0142owska J","year":"1996","unstructured":"Rafa\u0142owska J, , Dziewulska D. White matter injury in amyotrophic lateral sclerosis (ALS). Folia Neuropathol, 1996; 34(2):87\u201391.","journal-title":"Folia Neuropathol"},{"key":"e_1_3_5_225_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000065888.88988.6E"},{"key":"e_1_3_5_226_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1998.tb09680.x"},{"key":"e_1_3_5_227_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410380114"},{"key":"e_1_3_5_228_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13195-022-01074-9"},{"key":"e_1_3_5_229_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13578-023-01127-y"},{"key":"e_1_3_5_230_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(78)90142-9"},{"key":"e_1_3_5_231_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh041"},{"key":"e_1_3_5_232_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440621"},{"key":"e_1_3_5_233_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1426"},{"key":"e_1_3_5_234_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410270517"},{"key":"e_1_3_5_235_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2658"},{"key":"e_1_3_5_236_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2009.10.011"},{"key":"e_1_3_5_237_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2015.06.028"},{"key":"e_1_3_5_238_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2012.10.024"},{"key":"e_1_3_5_239_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.490420113"},{"key":"e_1_3_5_240_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.256.5058.843"},{"key":"e_1_3_5_241_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.6.1630"},{"key":"e_1_3_5_242_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.6.1149"},{"key":"e_1_3_5_243_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2010.02.009"},{"key":"e_1_3_5_244_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(89)90117-9"},{"key":"e_1_3_5_245_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1998.tb09688.x"},{"key":"e_1_3_5_246_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.490310116"},{"key":"e_1_3_5_247_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.02.016"},{"key":"e_1_3_5_248_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm0706-758"},{"key":"e_1_3_5_249_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature19323"},{"key":"e_1_3_5_250_1","doi-asserted-by":"publisher","DOI":"10.1177\/1759091418781889"},{"key":"e_1_3_5_251_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0901281"},{"key":"e_1_3_5_252_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0216390"},{"key":"e_1_3_5_253_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15112494"},{"key":"e_1_3_5_254_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1217775110"},{"key":"e_1_3_5_255_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2018.00051"},{"key":"e_1_3_5_256_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02641017"},{"key":"e_1_3_5_257_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1105681"},{"key":"e_1_3_5_258_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2105316118"},{"key":"e_1_3_5_259_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/126.11.2746"},{"key":"e_1_3_5_260_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddv372"},{"key":"e_1_3_5_261_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1994.63051802.x"},{"key":"e_1_3_5_262_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004010050717"},{"key":"e_1_3_5_263_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1994.62031039.x"},{"key":"e_1_3_5_264_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70170-X"},{"key":"e_1_3_5_265_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1525-17.2017"},{"key":"e_1_3_5_266_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R026682"},{"key":"e_1_3_5_267_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature20413"},{"key":"e_1_3_5_268_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.30.051606.094313"},{"key":"e_1_3_5_269_1","doi-asserted-by":"publisher","DOI":"10.1113\/EP087862"},{"key":"e_1_3_5_270_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0075720"},{"key":"e_1_3_5_271_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458508096685"},{"key":"e_1_3_5_272_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2212948"},{"key":"e_1_3_5_273_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31287-4"},{"key":"e_1_3_5_274_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-018-1835-x"},{"key":"e_1_3_5_275_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0024239"},{"key":"e_1_3_5_276_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu139"},{"key":"e_1_3_5_277_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202303411"},{"key":"e_1_3_5_278_1","doi-asserted-by":"publisher","DOI":"10.1212\/CON.0000000000001136"},{"key":"e_1_3_5_279_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn190"},{"key":"e_1_3_5_280_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-4-3"},{"key":"e_1_3_5_281_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027985"},{"key":"e_1_3_5_282_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191815"},{"key":"e_1_3_5_283_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.23090"},{"key":"e_1_3_5_284_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-011-0437-y"},{"key":"e_1_3_5_285_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-007-6331-9_3"},{"key":"e_1_3_5_286_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells8010027"},{"key":"e_1_3_5_287_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2010.12.014"},{"key":"e_1_3_5_288_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10719-015-9579-5"},{"key":"e_1_3_5_289_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-023-00592-z"},{"key":"e_1_3_5_290_1","doi-asserted-by":"publisher","DOI":"10.1177\/1179573520907397"},{"key":"e_1_3_5_291_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2011.07.045"},{"issue":"3","key":"e_1_3_5_292_1","first-page":"94","article-title":"Serum IgG and IgM ganglioside GM1 antibodies in patients with multiple sclerosis","volume":"57","author":"Zaprianova E","year":"2004","unstructured":"Zaprianova E, , Majtenyi K, , Deleva D, et al. Serum IgG and IgM ganglioside GM1 antibodies in patients with multiple sclerosis. Ideggyogy Sz, 2004; 57(3\u20134):94\u201399.","journal-title":"Ideggyogy Sz"},{"key":"e_1_3_5_293_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2008.05481.x"},{"key":"e_1_3_5_294_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2018.04.005"},{"key":"e_1_3_5_295_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.904399"},{"key":"e_1_3_5_296_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2023.125022"},{"key":"e_1_3_5_297_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-71510-z"},{"key":"e_1_3_5_298_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.612069"},{"key":"e_1_3_5_299_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2011000600009"},{"key":"e_1_3_5_300_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2017.7186"},{"key":"e_1_3_5_301_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2023.10.021"},{"key":"e_1_3_5_302_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.12.012"}],"container-title":["Antioxidants &amp; Redox Signaling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/ars.2024.0676","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/ars.2024.0676","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/ars.2024.0676","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:55:53Z","timestamp":1777377353000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/ars.2024.0676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":301,"journal-issue":{"issue":"16-18","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1089\/ars.2024.0676"],"URL":"https:\/\/doi.org\/10.1089\/ars.2024.0676","relation":{},"ISSN":["1523-0864","1557-7716"],"issn-type":[{"value":"1523-0864","type":"print"},{"value":"1557-7716","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]}}}