{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T13:15:04Z","timestamp":1782738904382,"version":"3.54.5"},"reference-count":27,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T00:00:00Z","timestamp":1458086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T00:00:00Z","timestamp":1458086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Breastfeeding Medicine"],"published-print":{"date-parts":[[2016,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Infants may benefit from early nutritional intervention to decrease hospital stay. To evaluate the effects of adding a human milk (HM)-derived cream (Cream) product to a standard feeding regimen in preterm infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>In a prospective multicenter randomized study, infants with birth weights 750\u20131,250\u2009g were assigned to a Control or Cream group. The Control group received a standard feeding regimen consisting of mother's own milk or donor HM with donor HM-derived fortifier. The Cream group received the standard feeding regimen along with an additional HM-derived cream supplement when the HM they received was &lt;20 kcal\/oz. Primary outcomes of this secondary analysis included comorbidities, length of stay (LOS), and postmenstrual age (PMA) at discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We enrolled 75 infants (Control\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200937, Cream\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200938) with gestational age 27.7\u2009\u00b1\u20091.8 weeks and birth weight 973\u2009\u00b1\u2009145\u2009g (mean \u00b1 SD). After adjusting for gestational age, birth weight, and presence of bronchopulmonary dysplasia (BPD), the Cream group had a decreased PMA at discharge (39.9\u2009\u00b1\u20094.8 versus 38.2\u2009\u00b1\u20092.7 weeks,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.03) and LOS (86\u2009\u00b1\u200939 versus 74\u2009\u00b1\u200922 days,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.05). For 21 infants with BPD, these values trended toward significance for PMA at discharge (44.2\u2009\u00b1\u20096.1 versus 41.3\u2009\u00b1\u20092.7 weeks,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.08) and LOS (121\u2009\u00b1\u200949 versus 104\u2009\u00b1\u200923 days,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.08).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Very preterm infants who received an HM-derived cream supplement were discharged earlier. Infants with BPD may have benefited the most.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/bfm.2015.0166","type":"journal-article","created":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T11:37:23Z","timestamp":1458128243000},"page":"133-137","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":30,"title":["Premature Infants 750\u20131,250\u2009g Birth Weight Supplemented with a Novel Human Milk-Derived Cream Are Discharged Sooner"],"prefix":"10.1177","volume":"11","author":[{"given":"Amy B.","family":"Hair","sequence":"first","affiliation":[{"name":"Texas Children's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erynn M.","family":"Bergner","sequence":"additional","affiliation":[{"name":"Texas Children's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin L.","family":"Lee","sequence":"additional","affiliation":[{"name":"Prolacta Bioscience"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro G.","family":"Moreira","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keli M.","family":"Hawthorne","sequence":"additional","affiliation":[{"name":"Dell Medical School at the University of Texas at Austin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Rechtman","sequence":"additional","affiliation":[{"name":"Prolacta Bioscience"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven A.","family":"Abrams","sequence":"additional","affiliation":[{"name":"Dell Medical School at the University of Texas at Austin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia L.","family":"Blanco","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,3,16]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2010.10.005"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.10.040"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.07.011"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2014.0024"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-3552"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2008.10.008"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2011.04.016"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.112.042689"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2006.05.007"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2011.67"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2007.02.001"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2013.07.005"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2014.07.005"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)34975-6"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.7.2011060"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-0913"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2386"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.07.013"},{"key":"e_1_3_3_20_2","doi-asserted-by":"crossref","first-page":"165","DOI":"10.2223\/JPED.1481","article-title":"Let's feed the preterm lung","volume":"82","author":"Jobe AH","year":"2006","unstructured":"Jobe AH. Let's feed the preterm lung. J Pediatr (Rio J), 2006; 82:165\u2013166.","journal-title":"J Pediatr (Rio J)"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2466-11-7"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00035.2002"},{"key":"e_1_3_3_23_2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.2223\/JPED.1471","article-title":"Pulmonary responses to nutritional restriction and hyperoxia in premature rabbits","volume":"82","author":"Mataloun MM","year":"2006","unstructured":"Mataloun MM, , Rebello CM, , Mascaretti RS, et al. Pulmonary responses to nutritional restriction and hyperoxia in premature rabbits. 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