{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T23:22:57Z","timestamp":1781997777490,"version":"3.54.5"},"reference-count":73,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Breastfeeding Medicine"],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Little is known about the biology of secretory activation (SA) in overweight and obese (OW\/OB) mothers who are breast pump dependent with a premature infant in the neonatal intensive care unit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>\n                      To compare time-dependent changes in daily pumped milk volume, maternal milk sodium (Na) concentration, and Na-to-potassium (K) ratios (Na:K) in the first 14 days postpartum in breast pump-dependent mothers with prepregnancy body mass index (BMI) &lt;27 and BMI \u226527\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design\/Methods:<\/jats:title>\n                    <jats:p>\n                      This secondary analysis for 39 subjects, 44% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200917) with prepregnancy BMI &lt;27 and 56% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200922) with BMI \u226527, included transformed data of outcome measures, chi-square,\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -tests, and growth curve models.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>For days 1\u20137, daily pumped milk volume increased significantly more rapidly for mothers with BMI &lt;27 (65.82\u2009mL\/d) versus BMI \u226527 (33.08\u2009mL\/d), but the daily rate of change in pumped milk volume during days 8\u201314 was not statistically different. Daily milk Na concentration decreased significantly faster in BMI &lt;27 (\u22123.93\u2009mM\/d) versus BMI \u226527 (\u22122.00\u2009mM\/day) during days 1\u20137, but was not significantly different for days 8\u201314. No statistical differences were noted for Na:K ratio for either time period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>These data add biologic evidence to previous research, suggesting delayed or impaired SA in OW\/OB mothers, and suggest that the window of opportunity for research and clinical interventions is days 1\u20137 postpartum in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/bfm.2021.0167","type":"journal-article","created":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T12:27:20Z","timestamp":1639744040000},"page":"173-181","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Prepregnancy Body Mass Index Is Associated with Time-Dependent Changes in Secretory Activation Measures During the First 7 Days Postpartum in Breast Pump-dependent Mothers of Premature Infants"],"prefix":"10.1177","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6593-0458","authenticated-orcid":false,"given":"Clarisa","family":"Medina Poeliniz","sequence":"first","affiliation":[{"name":"College of Nursing, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9457-8791","authenticated-orcid":false,"given":"Rebecca","family":"Hoban","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Rush University Medical Center, Chicago, Illinois, USA."},{"name":"Division of Neonatology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Schoeny","sequence":"additional","affiliation":[{"name":"College of Nursing, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet L.","family":"Engstrom","sequence":"additional","affiliation":[{"name":"Department of Women and Children's Nursing, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aloka L.","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Meier","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Rush University Medical Center, Chicago, Illinois, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,2,11]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/mcn.12865"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-020-03156-8"},{"key":"e_1_3_5_4_2","first-page":"1","article-title":"Increases in prepregnancy obesity: United states, 2016\u20132019","volume":"392","author":"Driscoll AK","year":"2020","unstructured":"Driscoll AK, , Gregory ECV. Increases in prepregnancy obesity: United states, 2016\u20132019. NCHS Data Brief, 2020; 392:1\u20138.","journal-title":"NCHS Data Brief"},{"key":"e_1_3_5_5_2","volume-title":"Cochrane Database Syst Rev","author":"Fair FJ","year":"2099","unstructured":"Fair FJ, , Ford GL, , Soltani H. Cochrane library database of systematic reviews. Cochrane Database Syst Rev. 2019, Issue 9. Art. No.: CD01, 2099."},{"key":"e_1_3_5_6_2","author":"Hauff LE","unstructured":"Hauff LE, , Demerath EW. Poor positioning, decreased prolactin levels, and low milk output associated with early cessation of exclusive breastfeeding in obese women. FASEB J 2012;26:368.2.","journal-title":"FASEB J"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(16)30217-0"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/oby.21532"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1698833"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2005.tb00113.x"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2013.4506"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2020.0006"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2019.0247"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.3945\/an.115.011007"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.3945\/jn.115.214619"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-0688"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2015.0047"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2012.10.007"},{"key":"e_1_3_5_19_2","author":"Chantry CJ","unstructured":"Chantry CJ, , Dewey KG, , Peerson JM, et al. In-hospital formula use increases early breastfeeding cessation among first-time mothers intending to exclusively breastfeed. J Pediatr 2014;164:1339\u20131345.e5.","journal-title":"J Pediatr"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/mcn.12344"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-017-1656-2"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.12784\/nzcomjnl51.2015.4.23-29"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2011.0007"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12288"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0000000000000650"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2017.0183"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1177\/0890334420980424"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1177\/0890334420940239"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1177\/1099800409331394"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/DBP.0000000000000174"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2020.09.010"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/48.6.1375"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(03)00033-4"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(05)70283-2"},{"key":"e_1_3_5_35_2","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2021.0046"},{"key":"e_1_3_5_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.2642"},{"key":"e_1_3_5_37_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.113905"},{"key":"e_1_3_5_38_2","unstructured":"Breastmilk ecology: Genesis of infant nutrition (BEGIN) meeting series working group 1: Maternal inputs. Available at https:\/\/videocast.nih.gov\/watch=40150 (accessed January15 2021). NIH Streaming United States; 2021."},{"key":"e_1_3_5_39_2","unstructured":"World Health Organization (WHO). Global health observatory data: Mean body mass index (BMI). Situation and trends. Available at https:\/\/www.who.int\/health-topics\/obesity#tab=tab_1 (accessed May3 2021)."},{"key":"e_1_3_5_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/66.6.1371"},{"key":"e_1_3_5_41_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.5.e465"},{"key":"e_1_3_5_42_2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.46.6.559"},{"key":"e_1_3_5_43_2","doi-asserted-by":"publisher","DOI":"10.1177\/0890334403261345"},{"key":"e_1_3_5_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(99)00109-1"},{"issue":"2","key":"e_1_3_5_45_2","first-page":"S188","article-title":"Maternal pre-pregnancy BMI independently predicts breastfeeding duration among successfully breastfeeding mothers","volume":"18","author":"Woo JG","year":"2010","unstructured":"Woo JG, , McMahon RJ, , Nommsen-Rivers AL, et al. Maternal pre-pregnancy BMI independently predicts breastfeeding duration among successfully breastfeeding mothers. Obesity, 2010; 18(S2):S188.","journal-title":"Obesity"},{"key":"e_1_3_5_46_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2010.29192"},{"key":"e_1_3_5_47_2","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2010.0014"},{"key":"e_1_3_5_48_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.113.059600"},{"key":"e_1_3_5_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2016.11.005"},{"key":"e_1_3_5_50_2","doi-asserted-by":"publisher","DOI":"10.1177\/0890334413491629"},{"key":"e_1_3_5_51_2","doi-asserted-by":"publisher","DOI":"10.1159\/000370058"},{"key":"e_1_3_5_52_2","first-page":"1","article-title":"Racial and socioeconomic disparities in breast milk feedings in US neonatal intensive care units","volume":"89","author":"Patel AL","year":"2020","unstructured":"Patel AL, , Johnson TJ, , Meier PP, et al. Racial and socioeconomic disparities in breast milk feedings in US neonatal intensive care units. Pediatr Res, 2020; 89:1\u20139.","journal-title":"Pediatr Res"},{"key":"e_1_3_5_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmwh.2007.07.009"},{"key":"e_1_3_5_54_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu10091218"},{"key":"e_1_3_5_55_2","doi-asserted-by":"crossref","unstructured":"Singer JD Willett JB. Applied Longitudinal Data Analysis: Modeling Changed and Event Occurrence. Oxford UK: Oxford University Press 2003.","DOI":"10.1093\/acprof:oso\/9780195152968.001.0001"},{"key":"e_1_3_5_56_2","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsp004"},{"key":"e_1_3_5_57_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8709.2012.00439.x"},{"key":"e_1_3_5_58_2","doi-asserted-by":"publisher","DOI":"10.1177\/0890334417727716"},{"key":"e_1_3_5_59_2","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2011.64"},{"key":"e_1_3_5_60_2","first-page":"67","article-title":"Breast-milk sodium as a predictor of breastfeeding patterns","volume":"30","author":"Humenick SS","year":"1998","unstructured":"Humenick SS, , Hill PD, , Thompson HJ, et al. Breast-milk sodium as a predictor of breastfeeding patterns. Can J Nurs Res, 1998; 30:67\u201381.","journal-title":"Can J Nurs Res"},{"key":"e_1_3_5_61_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-015-1858-z"},{"key":"e_1_3_5_62_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjhp.12246"},{"key":"e_1_3_5_63_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00337.2013"},{"key":"e_1_3_5_64_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00495.2015"},{"key":"e_1_3_5_65_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu12082209"},{"key":"e_1_3_5_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.midw.2015.02.001"},{"key":"e_1_3_5_67_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu13010019"},{"key":"e_1_3_5_68_2","doi-asserted-by":"publisher","DOI":"10.1111\/mcn.12783"},{"key":"e_1_3_5_69_2","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2007.0021"},{"key":"e_1_3_5_70_2","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2016.14"},{"key":"e_1_3_5_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2016.11.005"},{"key":"e_1_3_5_72_2","first-page":"890334421993467","article-title":"Proactive lactation care is associated with improved outcomes in a referral NICU","author":"Hoban R","year":"2021","unstructured":"Hoban R, , McLean L, , Sullivan S. Proactive lactation care is associated with improved outcomes in a referral NICU. J Hum Lact, 2021; 890334421993467.","journal-title":"J Hum Lact"},{"key":"e_1_3_5_73_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10911-007-9054-4"},{"key":"e_1_3_5_74_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2747"}],"container-title":["Breastfeeding Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/bfm.2021.0167","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/bfm.2021.0167","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/bfm.2021.0167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:00:42Z","timestamp":1777381242000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/bfm.2021.0167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,1]]},"references-count":73,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2,1]]}},"alternative-id":["10.1089\/bfm.2021.0167"],"URL":"https:\/\/doi.org\/10.1089\/bfm.2021.0167","relation":{},"ISSN":["1556-8253","1556-8342"],"issn-type":[{"value":"1556-8253","type":"print"},{"value":"1556-8342","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,1]]}}}