{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:15:33Z","timestamp":1780442133440,"version":"3.54.1"},"reference-count":32,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Breastfeeding Medicine"],"published-print":{"date-parts":[[2025,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Cow\u2019s milk protein allergy (CMPA) is the most common food allergy in infants. The current standard of care (SOC) involves eliminating the allergen from both the infant\u2019s and mother\u2019s diet for 2\u20134 weeks. The purpose of this study is to assess the effectiveness of\n                      <jats:italic toggle=\"yes\">Lactobacillus rhamnosus<\/jats:italic>\n                      (Ramnoflor) in reducing the duration of bleeding in these infants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This randomized clinical trial was conducted at Bahrami Children\u2019s Hospital on breastfed infants who were diagnosed with CMPA and had a positive occult blood (OB) test. Patients were randomly assigned to either the control or case groups. All patients received SOC therapy, with the case group receiving Ramnoflor and the control group receiving a placebo. Data were recorded on the checklist, and the children were followed and visited three times during the study, with an OB assessment at each visit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study enrolled 48 infants. Among the infants in the case group, the OB test was positive in four cases (8.3%) on the fifth day. However, there were no positive cases on the 14th and 30th days. The prevalence of this test was significantly lower in patients who received probiotics compared to the control group on the fifth day (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). There were no positive OB tests on the 14th and 30th days in any of the groups, and no significant difference was observed between the groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      The addition of\n                      <jats:italic toggle=\"yes\">L. rhamnosus<\/jats:italic>\n                      to SOC therapy led to a decrease in the duration of rectal bleeding in infants with CMPA compared to the control group.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/bfm.2024.0185","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T05:19:37Z","timestamp":1729142377000},"page":"59-64","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["<i>Lactobacillus rhamnosus<\/i>\n                    Helps to Reduce the Duration of Bleeding in Breastfed Infants with Allergic Proctocolitis"],"prefix":"10.1177","volume":"20","author":[{"given":"Armen","family":"Malekiantaghi","sequence":"first","affiliation":[{"name":"Department of Pediatric, Bahrami Children\u2019s Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faezeh","family":"Ghanaati","sequence":"additional","affiliation":[{"name":"Department of Pediatric, Bahrami Children\u2019s Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hosein","family":"Shabani-Mirzaee","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology, Bahrami Children\u2019s Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamak","family":"Shariat","sequence":"additional","affiliation":[{"name":"Maternal, Fetal &amp; Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayed-Yousef","family":"Mojtahedi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology, Bahrami Children\u2019s Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3471-2498","authenticated-orcid":false,"given":"Kambiz","family":"Eftekhari","sequence":"additional","affiliation":[{"name":"Department of Pediatric, Pediatric Gastroenterology and Hepatology Research Center, Bahrami Children\u2019s Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,1,15]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.5114\/ada.2019.90120"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2019.00372"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-019-03397-6"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.18520\/cs\/v118\/i9\/1375-1378"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.2174\/1871530314666140121145800"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0000000000000644"},{"issue":"3","key":"e_1_3_5_8_2","article-title":"Alergia a las prote\u00ednas de leche de vaca no mediada por IgE: Documento de consenso de la Sociedad Espa\u00f1ola de Gastroenterolog\u00eda, Hepatolog\u00eda y Nutrici\u00f3n Pedi\u00e1trica (SEGHNP), la Asociaci\u00f3n Espa\u00f1ola de Pediatr\u00eda de Atenci\u00f3n Primaria (AEPAP), la Sociedad Espa\u00f1ola de Pediatr\u00eda Extrahospitalaria y Atenci\u00f3n Primaria (SEPEAP) y la Sociedad Espa\u00f1ola de Inmunolog\u00eda Cl\u00ednica, Alergolog\u00eda y Asma Pedi\u00e1trica (SEICAP)","volume":"90","author":"Esp\u00edn Jaime B","year":"2019","unstructured":"Esp\u00edn Jaime B, , D\u00edaz Mart\u00edn JJ, , Blesa Baviera LC, et al. Alergia a las prote\u00ednas de leche de vaca no mediada por IgE: Documento de consenso de la Sociedad Espa\u00f1ola de Gastroenterolog\u00eda, Hepatolog\u00eda y Nutrici\u00f3n Pedi\u00e1trica (SEGHNP), la Asociaci\u00f3n Espa\u00f1ola de Pediatr\u00eda de Atenci\u00f3n Primaria (AEPAP), la Sociedad Espa\u00f1ola de Pediatr\u00eda Extrahospitalaria y Atenci\u00f3n Primaria (SEPEAP) y la Sociedad Espa\u00f1ola de Inmunolog\u00eda Cl\u00ednica, Alergolog\u00eda y Asma Pedi\u00e1trica (SEICAP). An Pediatr (Engl Ed), 2019; 90(3):193.e1\u2013193.e11; doi: 10.1016\/j.anpedi.2018.11.007Spanish;","journal-title":"An Pediatr (Engl Ed)"},{"issue":"3","key":"e_1_3_5_9_2","first-page":"200","article-title":"Cow\u2019s milk protein allergy; new knowledge from a multidisciplinary perspective","volume":"120","author":"Mehaudy R","year":"2022","unstructured":"Mehaudy R, , J\u00e1uregui MB, , Vinderola G, et al. Cow\u2019s milk protein allergy; new knowledge from a multidisciplinary perspective. 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