{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T04:48:40Z","timestamp":1784177320521,"version":"3.55.0"},"reference-count":39,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Brain Connectivity"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Accurate diagnosis of cerebral ischemia severity is crucial for clinical decision making. Laser speckle contrast imaging-based cerebral blood flow imaging can help assess the severity of cerebral ischemia by monitoring changes in blood flow.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>In this study, we simulated hyperacute ischemia in rats, isolating arterial and venous flow-related signals from cortical vasculature. Pearson correlation was used to examine the correlation between damaged vessels. Granger causality analysis was used to investigate causality correlation in ischemic vessels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Resting state analysis revealed a negative Pearson correlation between regional arteries and veins. Following cerebral ischemia induction, a positive artery\u2013vein correlation emerged, which vanished after blood flow reperfusion. Granger causality analysis demonstrating enhanced causality coefficients for middle artery\u2013vein pairs during occlusion, with a stronger left-right arterial effect than that of right-left, which persisted after reperfusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>These processing approaches amplify the understanding of cerebral ischemic images, promising potential future diagnostic advancements.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/brain.2024.0026","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T07:28:58Z","timestamp":1726644538000},"page":"459-470","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessment of Hyperacute Cerebral Ischemia Using Laser Speckle Contrast 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