{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T01:50:39Z","timestamp":1792979439196,"version":"4.5.0"},"reference-count":20,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Child and Adolescent Psychopharmacology"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>To protect against osteoporosis, keeping the vitamin D blood level (25[OH]D; VDBL) above 30\u2009ng\/mL is recommended. It is established that regular intake of vitamin D, calcium intake, and physical exercise contribute to maximizing bone mineral mass during childhood and adolescence. Recent articles suggest that patients with schizophrenia treated with antipsychotics have low VDBL and may have a higher risk of hip fractures in their later years than the general population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To evaluate whether adolescent psychiatric inpatient VDBL is lower than the 30-ng\/mL optimal threshold and to document low-VDBL risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>\n                      We determined the VDBL of all consecutive inpatients from three adolescents units in 2009 (\n                      <jats:italic toggle=\"yes\">N<\/jats:italic>\n                      \u2009=\u2009136). Univariate analyses explored the influence on VDBL of (1) well-documented risk factors (e.g., age, gender, ethnic origin, body mass index, or season) and (2) suspected risk factors (e.g., disease type or antipsychotic treatment).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      All but six patients had a VDBL &lt;30\u2009ng\/mL (mean [\u2009\u00b1\u2009SD]: 15.9 [\u2009\u00b1\u20098.4] ng\/mL). VDBL was significantly lower for all patients during the first quarter of the year compared to the other three (all\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.01). VDBL was also lower for blacks\/North Africans 12.8 (\u00b17.0) than for Caucasians\/Europeans 17.2 (\u00b18.5):\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      \u2009=\u20092.62,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.009. We found no differences between patients regarding disease category (\n                      <jats:italic toggle=\"yes\">K<\/jats:italic>\n                      \u2009=\u20093.75,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.154) or antipsychotic treatment (\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      \u2009=\u20090.127, df\u2009=\u2009124,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.89).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>VDBL in an adolescent population with severe mental illness is lower than current recommendations of optimal level for bone health regardless of treatment or disease type. Because adolescence is a period of bone construction and could represent a critical window of opportunity for maximizing bone mass, especially among patients with severe mental illness, we recommend vitamin D supplementation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/cap.2010.0079","type":"journal-article","created":{"date-parts":[[2011,4,12]],"date-time":"2011-04-12T20:02:28Z","timestamp":1302638548000},"page":"157-161","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Children and Adolescents with Severe Mental Illness Need Vitamin D Supplementation Regardless of Disease or Treatment"],"prefix":"10.1177","volume":"21","author":[{"given":"Olivier","family":"Bonnot","sequence":"first","affiliation":[{"name":"Groupe Hospitalier Piti\u00e9 Salp\u00e9triere","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachida","family":"Inaoui","sequence":"additional","affiliation":[{"name":"Groupe Hospitalier Piti\u00e9 Salp\u00e9triere","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Raffin-Viard","sequence":"additional","affiliation":[{"name":"Groupe Hospitalier Piti\u00e9 Salp\u00e9triere","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Bodeau","sequence":"additional","affiliation":[{"name":"Groupe Hospitalier Piti\u00e9 Salp\u00e9triere","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Coussieu","sequence":"additional","affiliation":[{"name":"Groupe Hospitalier Piti\u00e9 Salp\u00e9triere","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Cohen","sequence":"additional","affiliation":[{"name":"Groupe Hospitalier Piti\u00e9 Salp\u00e9triere","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,4,1]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(95)00062-L"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119287"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","unstructured":"Bonnot O Inaoui R Lloret C Cohen D. Surveillance of metabolic syndrome hyperprolactinemia cardiac side effects in children adolescent treated with antipsychotic. Actuality and recommendations. Neuropsychiatrie de l'Enfance et de l'Adolescence[Epub ahead of print]10.1016\/j.neurenf.2009.09.004 2009.","DOI":"10.1016\/j.neurenf.2009.09.004"},{"key":"e_1_3_2_5_1","volume-title":"The History Geography of Human Genes","author":"Cavalli-Sforza LL","year":"1994","unstructured":"Cavalli-Sforza LL, , Menozzi P, , Piazza A. The History Geography of Human Genes. Princeton, NJ: Princeton University Press, 1994."},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-005-1867-7"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2008.604"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/22.3.447"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200721080-00003"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-006-0049-8"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-996-0028-z"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.106.023671"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.1.162"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001980170112"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2000.15.4.721"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-62-3-503"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.jcp.0000150223.31007.e0"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2009.10.005"},{"key":"e_1_3_2_19_1","doi-asserted-by":"crossref","unstructured":"Rizzoli R Boonen S Brandi ML Nansa Burlet N Delmas PD Kanis J Reginster JY. Calcium vitamin D in the management of osteoporosis. Eur Soc Clin Econ Aspects Osteoporos Arthritis 2009. www.iofbonehealth.org\/download\/osteofound\/filemanager\/iof\/csa\/pdf\/calcium-vitaminD-ESCEO.pdf.","DOI":"10.1016\/j.bone.2007.10.005"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030817"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1862"}],"container-title":["Journal of Child and Adolescent Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/cap.2010.0079","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/cap.2010.0079","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/cap.2010.0079","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:55:00Z","timestamp":1777388100000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/cap.2010.0079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1089\/cap.2010.0079"],"URL":"https:\/\/doi.org\/10.1089\/cap.2010.0079","relation":{},"ISSN":["1044-5463","1557-8992"],"issn-type":[{"value":"1044-5463","type":"print"},{"value":"1557-8992","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4]]}}}