{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:12:06Z","timestamp":1777493526859,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Child and Adolescent Psychopharmacology"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Method:<\/jats:italic>\n                    <\/jats:bold>\n                    An open, naturalistic observational study design was used, in which a sample of seven boys between 10 and 14 years of age was assessed over 26 weeks.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    The subjects were all diagnosed with conduct disorder (CD) and exhibited high levels of aggression that were refractory to psychosocial approaches (parent counseling, school counseling, and psychotherapy) and to more than three pharmacological treatments. Levels of aggression, side effects, and hematological parameters were evaluated weekly. Clinical response was evaluated using the standardized instruments Clinical Global Impressions (CGI) and Child Behavior Check List (CBCL) 6\u201318 before starting medication and after 26 weeks.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusion:<\/jats:italic>\n                    <\/jats:bold>\n                    We observed good tolerability of clozapine in doses from 100 to 600\u2009mg\/day with no significant side effects or hematological changes. The CGI and CBCL 6\u201318 scales indicated that clozapine led to a marked control of symptoms.\n                  <\/jats:p>","DOI":"10.1089\/cap.2011.0148","type":"journal-article","created":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T10:03:49Z","timestamp":1359021829000},"page":"44-48","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Clozapine in Severe Conduct Disorder"],"prefix":"10.1177","volume":"23","author":[{"given":"Eduardo H.","family":"Teixeira","sequence":"first","affiliation":[{"name":"State University of Campinas (UNICAMP)","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eloisa V.","family":"Celeri","sequence":"additional","affiliation":[{"name":"State University of Campinas (UNICAMP)","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio C. A.","family":"Jacintho","sequence":"additional","affiliation":[{"name":"State University of Campinas (UNICAMP)","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Dalgalarrondo","sequence":"additional","affiliation":[{"name":"State University of Campinas (UNICAMP)","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,2,1]]},"reference":[{"key":"e_1_3_2_2_1","volume-title":"Mental Health Practitioner's Guide for the Achenbach System of Empirically Based Assessment (ASEBA)","author":"Achenbach TR","year":"2004","unstructured":"Achenbach TR. 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