{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:01:16Z","timestamp":1792144876348,"version":"4.4.0"},"reference-count":76,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Child and Adolescent Psychopharmacology"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1089\/cap.2014.0146","type":"journal-article","created":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T15:07:00Z","timestamp":1430233620000},"page":"286-292","source":"Crossref","is-referenced-by-count":29,"title":["Neurogenetic and Epigenetic Correlates of Adolescent Predisposition to and Risk for Addictive Behaviors as a Function of Prefrontal Cortex Dysregulation"],"prefix":"10.1177","volume":"25","author":[{"given":"Kenneth","family":"Blum","sequence":"first","affiliation":[{"name":"Department of Psychiatry and McKnight Brain Institute, University of Florida, College of Medicine, Gainesville, Florida."},{"name":"Division of Addiction Services, Dominion Diagnostics, LLC, North Kingstown, Rhode Island."},{"name":"Department of Addiction Research &amp; Therapy, Malibu Beach Recovery Center, Malibu Beach, California."},{"name":"Human Integrative Services &amp; Translational Science, Department of Psychiatry, University of Vermont College of Medicine, Burlington, Vermont."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Febo","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and McKnight Brain Institute, University of Florida, College of Medicine, Gainesville, Florida."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Smith","sequence":"additional","affiliation":[{"name":"Division of Addiction Services, Dominion Diagnostics, LLC, North Kingstown, Rhode Island."},{"name":"Institute of Health &amp; Aging, University of California, San Francisco, California."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"A. Kenison","family":"Roy","sequence":"additional","affiliation":[{"name":"Behavioral Medical Corporation, Metairie, Louisiana."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsolt","family":"Demetrovics","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Addiction, Institute of Psychology, E\u00f6tv\u00f6s Lor\u00e1nd University, Budapest, Hungary."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frans J.","family":"Cronj\u00e9","sequence":"additional","affiliation":[{"name":"University of Stellenbosch, Cape Town, South Africa."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Femino","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Meadows Edge Recovery Center, North Kingston, Rhode Island."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gozde","family":"Agan","sequence":"additional","affiliation":[{"name":"Division of Addiction Services, Dominion Diagnostics, LLC, North Kingstown, Rhode Island."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James L.","family":"Fratantonio","sequence":"additional","affiliation":[{"name":"Division of Applied Clinical Research, Dominion Diagnostics, LLC, North Kingstown, Rhode Island."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhash C.","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajendra D.","family":"Badgaiyan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Minnesota College of Medicine, Minneapolis, Minnesota."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Gold","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and McKnight Brain Institute, University of Florida, College of Medicine, Gainesville, Florida."},{"name":"Department of Addiction Research &amp; Therapy, Malibu Beach Recovery Center, Malibu Beach, California."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2013.12121597"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1492(199706\/08)10:4\/5<165::AID-NBM454>3.0.CO;2-7"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4000261"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1007\/BF01940430"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-008-0093-z"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.2012.685407"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph8124425"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.2174\/138161212798919110"},{"key":"B10","volume":"3","author":"Blum K","year":"2012","journal-title":"J Genet Syndr Gene Ther"},{"key":"B11","volume":"3","author":"Blum K","year":"2012","journal-title":"J Genet Syndr Gene Ther"},{"key":"B12","first-page":"139","volume":"3","author":"Blum K","year":"2012","journal-title":"J Addict Res Ther"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.3810\/psm.2014.05.2065"},{"key":"B14","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1177\/014107689608900711","volume":"89","author":"Blum K","year":"1996","journal-title":"J R Soc Med"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.4172\/2155-6105.1000169"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1556\/JBA.3.2014.019"},{"key":"B17","first-page":"1","volume":"6","author":"Blum K","year":"2014","journal-title":"Postgrad Med."},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-008-0093-z"},{"key":"B19","volume":"4","author":"Campbell H","year":"2013","journal-title":"J Genet Syndr Gene Ther"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4119-05.2005"},{"key":"B21","unstructured":"DailyJ: Adolescent and Young Adult Addiction: The Pathological Relationship to Intoxication and the Interpersonal Neurobiology Underpinnings. Sacramento, CA: Present Recovery Happens Counseling Services; 2012."},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1097\/01.alc.0000179368.87886.76"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2013.255"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1126\/science.1158668"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2013.22"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1011687108"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(95)00193-X"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1177\/0146167208321484"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2014.01.2735"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.2174\/138920008783884821"},{"key":"B31","doi-asserted-by":"crossref","first-page":"3","DOI":"10.7334\/psicothema2012.327","volume":"25","author":"Gonzalez\u2013Pardo H","year":"2013","journal-title":"Psicothema"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2011.00021"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2013.01.027"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0069043"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2014.04.020"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-014-0562-7"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.30830"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2009.110"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2013.03.020"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2014.50"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2010.07148.x"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1097\/00041444-200506000-00010"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1177\/1099800412463602"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2012.01.033"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2013.08.023"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.30255"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2014.00017"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2013.11.018"},{"key":"B49","first-page":"144","volume":"2","author":"Maksimovskiy AL","year":"2014","journal-title":"J Alcohol Drug Depend"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3670"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1556\/JBA.2.2013.2.8"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2006.05.020"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700013192"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1990.01810210057008"},{"key":"B55","doi-asserted-by":"crossref","first-page":"431","DOI":"10.31887\/DCNS.2013.15.4\/enestler","volume":"15","author":"Nestler EJ","year":"2013","journal-title":"Dialogues Clin Neurosci"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1111\/j.1369-1600.2011.00413.x"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2008.05835.x"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2014.03.016"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1994.00540210046012"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-801311-3.00002-0"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2008.06.004"},{"key":"B62","first-page":"1","volume":"26","author":"Sakharkar AJ","year":"2014","journal-title":"Int J Neuropsychopharmacol"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-183X.2011.00708.x"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1159\/000079111"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1016\/j.psc.2011.12.001"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1375\/twin.10.2.285"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.2012.662105"},{"key":"B68","first-page":"115","volume":"24","author":"Spear L","year":"2000","journal-title":"Alcohol Res Health"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2012.03.014"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgg.2013.06.004"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1007\/s12402-014-0139-9"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579413000795"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1016\/j.appet.2009.11.006"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2013.4"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2013.06.025"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.2466\/pr0.2002.91.3.743"}],"container-title":["Journal of Child and Adolescent Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/cap.2014.0146","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/cap.2014.0146","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:56:21Z","timestamp":1777388181000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/cap.2014.0146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":76,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1089\/cap.2014.0146"],"URL":"https:\/\/doi.org\/10.1089\/cap.2014.0146","relation":{},"ISSN":["1044-5463","1557-8992"],"issn-type":[{"value":"1044-5463","type":"print"},{"value":"1557-8992","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5]]}}}