{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T07:06:29Z","timestamp":1779692789329,"version":"3.53.1"},"reference-count":36,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Child and Adolescent Psychopharmacology"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Despite numerous studies regarding obesity (OB) in adult bipolar disorder (BP), there are few studies on this topic among adolescents. The current study attempts to extend the literature on prevalence and correlates of OB in adolescent BP by including control participants, and determining OB by direct measurement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Participants were 75 treatment-seeking adolescents, ages 13\u201319 years, with BP-I, -II, or -not otherwise specified, and 47 adolescents without major psychiatric illness. Diagnoses and clinical characteristics were assessed using the Kiddie Schedule for Affective Disorders and Schizophrenia for School Age Children, Present and Lifetime version (KSADS-PL). Family psychiatric history was assessed using the Family History Screen. OB was defined as adjusted body-mass index \u226595th percentile. Variables associated with OB in univariate analyses informed variable selection for within-group logistic regression analysis among BP adolescents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      BP participants had a significantly higher rate of OB (18%) compared to controls (4%; \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20095.3;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.02). BP remained a significant predictor for OB when controlling for race (odds ratio [OR]\u2009=\u20095.1, 95% confidence interval [CI]\u2009=\u20091.1\u201324.0,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.04). In univariate analyses among BP adolescents, OB was significantly associated with suicide attempt, self-injurious behavior, and oppositional defiant disorder. In multivariable analyses, suicide attempt and antidepressants that were not selective serotonin reuptake inhibitors were significantly associated with OB.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>OB is excessively prevalent among adolescents with BP and is associated with proxies for illness severity, including suicide attempts. Additional research is warranted to identify strategies to prevent and treat OB among BP adolescents, and to elucidate processes underlying the elevated risk of suicide attempts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/cap.2015.0154","type":"journal-article","created":{"date-parts":[[2016,1,15]],"date-time":"2016-01-15T17:09:47Z","timestamp":1452877787000},"page":"95-100","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":32,"title":["Controlled Study of Obesity Among Adolescents with Bipolar Disorder"],"prefix":"10.1177","volume":"27","author":[{"given":"Joshua","family":"Shapiro","sequence":"first","affiliation":[{"name":"Sunnybrook Health Sciences Centre","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Mindra","sequence":"additional","affiliation":[{"name":"Sunnybrook Health Sciences Centre","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Timmins","sequence":"additional","affiliation":[{"name":"Sunnybrook Health Sciences Centre","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda","family":"Swampillai","sequence":"additional","affiliation":[{"name":"Sunnybrook Health Sciences Centre","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonette","family":"Scavone","sequence":"additional","affiliation":[{"name":"Sunnybrook Health Sciences Centre","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katelyn","family":"Collinger","sequence":"additional","affiliation":[{"name":"Sunnybrook Health Sciences Centre","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Collins","sequence":"additional","affiliation":[{"name":"Sunnybrook Health Sciences Centre","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin I.","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Sunnybrook Health Sciences Centre","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,2,1]]},"reference":[{"key":"e_1_3_3_2_1","unstructured":"American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders 4th ed. 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