{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:17:20Z","timestamp":1777493840829,"version":"3.51.4"},"reference-count":47,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Child and Adolescent Psychopharmacology"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Prescription of second-generation antipsychotics (SGAs) in youth is rapidly increasing globally and in Australia. Lack of timely metabolic monitoring for potential adverse effects puts youth at greater risk for lifelong adverse health impact. Metabolic monitoring is recommended as best practice to prevent and\/or manage SGA-induced weight gain\/metabolic syndrome. The adherence to clinical guidelines remains suboptimal. It is crucial to gauge insight to challenges and strategies from the perspective of prescribers and to recommend strategies in promoting quality use of SGAs and adherence to pharmacovigilance standards.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Psychiatrists participated through semistructured interviews within the community mental health clinics in the Queensland State of Australia. The interviews focused on barriers to monitoring and strategies to enhance rate of monitoring with key focus on practical strategies for future implications in community setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Ten participants completed the interviews. Barriers were specified such as lack of adequate resources to conduct monitoring, carers' disengagement in their youth's treatments, and patients' refusal to undergo blood tests. Strategies to enhance metabolic monitoring heavily relied on organizational support, provision of training, and education opportunities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Clinical recommendations require mental health providers to facilitate conduction of metabolic monitoring among youth prescribed SGA\/s. However, they are not provided with enough support and there are challenges that prevent such care. It is crucial to understand the challenges in managing a complex and vulnerable patient cohort. This research has thrown light on these key aspects of existing gap between best practice standards and clinical practice in youth prescribed SGAs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/cap.2022.0021","type":"journal-article","created":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T10:48:23Z","timestamp":1654512503000},"page":"296-303","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Practitioners' Perspective on Metabolic Monitoring of Second-Generation Antipsychotics: Existing Gaps in Knowledge, Barriers to Monitoring, and Strategies"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9297-6737","authenticated-orcid":false,"given":"Nisreen","family":"Aouira","sequence":"first","affiliation":[{"name":"School of Pharmacy and Medical Sciences, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohil","family":"Khan","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Medical Sciences, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia."},{"name":"Mater Research Institute, The University of Queensland, Brisbane, Queensland, Australia."},{"name":"Prasanna Institute of Public Health and Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Heussler","sequence":"additional","affiliation":[{"name":"Mater Research Institute, The University of Queensland, Brisbane, Queensland, Australia."},{"name":"Children's Health Queensland Hospital and Health Services, South Brisbane, Queensland, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Haywood","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Medical Sciences, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia."},{"name":"Mater Research Institute, The University of Queensland, Brisbane, Queensland, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Karaksha","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Medical Sciences, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Bor","sequence":"additional","affiliation":[{"name":"Mater Research Institute, The University of Queensland, Brisbane, Queensland, Australia."},{"name":"Children's Health Queensland Hospital and Health Services, South Brisbane, Queensland, Australia."},{"name":"Child and Youth Mental Health Service, Centre for Children's Health Research, Queensland Health, Brisbane, Queensland, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,6,14]]},"reference":[{"key":"e_1_3_3_2_1","unstructured":"AIHW: Australian Institute of Health and Welfare . Mental health services in Australia 2018. https:\/\/www.aihw.gov.au\/reports\/mentalhealth-services\/mental-health-services-in-australia\/report-contents\/mentalhealth-related-prescriptions (accessed March15 2020)."},{"key":"e_1_3_3_3_1","doi-asserted-by":"crossref","unstructured":"Braun V Clarke V Hayfield N Terry G: Thematic analysis. In: Liamputtong P (ed.) Handbook of Research Methods in Health Social Sciences. Springer L. P. Singapore 2019.","DOI":"10.1007\/978-981-10-5251-4_103"},{"key":"e_1_3_3_4_1","first-page":"11","article-title":"What about N?","volume":"11","author":"Carlsen B","year":"2011","unstructured":"Carlsen B, , Glenton C: What about N?. A methodological study of sample-size reporting in focus group studies. BMC Med Res Methodol, 11:11, 2011.","journal-title":"A methodological study of sample-size reporting in focus group studies. BMC Med Res Methodol"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1549"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/inm.12417"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/10398560902980673"},{"key":"e_1_3_3_8_1","first-page":"138","article-title":"Physical illness in patients with severe mental disorders","volume":"10","author":"De Hert M","year":"2011","unstructured":"De Hert M, , Cohen D, , Bobes J, , Cetkovich-Bakmas M, , Leucht S, , Ndetei DM, , Newcomer JW, , Uwakwe R, , Asai I, , and M\u00f6ller HJ: Physical illness in patients with severe mental disorders. II. Barriers to care, monitoring and treatment guidelines, plus recommendations at the system and individual level. World Psychiatry, 10:138\u2013151, 2011.","journal-title":"II. Barriers to care, monitoring and treatment guidelines, plus recommendations at the system and individual level. World Psychiatry"},{"key":"e_1_3_3_9_1","article-title":"Semistructured interviewing in primary care research: A balance of relationship and rigour","volume":"7","author":"DeJonckheere M","year":"2019","unstructured":"DeJonckheere M, , Vaughn LM: Semistructured interviewing in primary care research: A balance of relationship and rigour. Fam Med Community Health, 7:e000057, 2019.","journal-title":"Fam Med Community Health"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.childyouth.2018.05.007"},{"key":"e_1_3_3_11_1","unstructured":"Dieleman M Harnmeijer JW : Improving Health Worker Performance: In search of Promising Practices. Geneva World Health Organization 2006."},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/10398561003692571"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-3147.139989"},{"key":"e_1_3_3_14_1","first-page":"59","article-title":"How many interviews are enough?","volume":"18","author":"Guest G","year":"2006","unstructured":"Guest G, , Bunce A, , Johnson L: How many interviews are enough?. An experiment with data saturation and variability. Field Methods, 18:59\u201382, 2006.","journal-title":"An experiment with data saturation and variability. Field Methods"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0232076"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-016-0814-9"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2008.08030383"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10597-015-9848-6"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/10398561003731189"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jan.13031"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13034-017-0192-1"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/10398562.2011.562508"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1478-4491-2-5"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/09638237.2010.510155"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.109.070466"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049732315617444"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2019.03.180176"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.002542012"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/famp.12235"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201500553"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2007.12.487"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-011-0215-5"},{"key":"e_1_3_3_33_1","first-page":"344","article-title":"Metabolic screening in children receiving antipsychotic drug treatment","volume":"164","author":"Morrato EH","year":"2010","unstructured":"Morrato EH, , Nicol GE, , Maahs D, , Druss BG, , Hartung DM, , Valuck RJ, , Campagna E, , Newcomer JW: Metabolic screening in children receiving antipsychotic drug treatment. Arch Pediatri Adolesc Med, 164:344\u2013351, 2010.","journal-title":"Arch Pediatri Adolesc Med"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10591-017-9423-0"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2012.08.031"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12961-022-00815-4"},{"key":"e_1_3_3_37_1","first-page":"22B","article-title":"The Canadian Alliance for Monitoring Effectiveness and Safety of Antipsychotics in Children (CAMESA) guideline group","volume":"17","author":"Pringsheim T","year":"2012","unstructured":"Pringsheim T, , Doja A, , Belanger S, , Patten S: The Canadian Alliance for Monitoring Effectiveness and Safety of Antipsychotics in Children (CAMESA) guideline group. Treatment recommendations for extrapyramidal side effects associated with second-generation antipsychotic use in children and youth. Paediatr Child Health, 17:22B\u201330B, 2012.","journal-title":"Treatment recommendations for extrapyramidal side effects associated with second-generation antipsychotic use in children and youth. Paediatr Child Health"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7893.2008.00108.x"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2013.07.014"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-139X(99)00068-3"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2014.0156"},{"key":"e_1_3_3_42_1","first-page":"134","article-title":"Barriers and facilitators to implementation of a metabolic monitoring protocol in hospital and community settings for second-generation antipsychotic-treated youth","volume":"20","author":"Ronsley R","year":"2011","unstructured":"Ronsley R, , Raghuram K, , Davidson J, , Panagiotopoulos C: Barriers and facilitators to implementation of a metabolic monitoring protocol in hospital and community settings for second-generation antipsychotic-treated youth. J Can Acad Child Adolesc Psychiatry, 20:134, 2011.","journal-title":"J Can Acad Child Adolesc Psychiatry"},{"key":"e_1_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2015.0285"},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1997.tb04773.x"},{"key":"e_1_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638237.2019.1581340"},{"key":"e_1_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/nhs.12048"},{"key":"e_1_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-018-0594-7"},{"key":"e_1_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1080\/10398560801958549"}],"container-title":["Journal of Child and Adolescent Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/cap.2022.0021","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/cap.2022.0021","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/cap.2022.0021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:56:25Z","timestamp":1777388185000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/cap.2022.0021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1089\/cap.2022.0021"],"URL":"https:\/\/doi.org\/10.1089\/cap.2022.0021","relation":{},"ISSN":["1044-5463","1557-8992"],"issn-type":[{"value":"1044-5463","type":"print"},{"value":"1557-8992","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6]]}}}