{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T04:48:23Z","timestamp":1785386903075,"version":"3.55.0"},"reference-count":47,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Child and Adolescent Psychopharmacology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Psychiatric disorders, including attention-deficit\/hyperactivity disorder (ADHD), may serve as a risk factor for child abuse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This study aimed to evaluate the association between children and adolescents with ADHD diagnosis and the risk of child abuse. The effectiveness of a pharmacological intervention on reducing the risk of child abuse was also assessed. A nationwide, population-based, retrospective with a matched-cohort study design was used. Data were from the National Health Insurance Research Database of Taiwan over a 15-year period (2000\u20132015).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Increased risk of child abuse in the ADHD group was noticed and the adjusted hazard ratio (HR) was 1.797 (95% confidence interval [CI]\u2009=\u20091.245\u20132.388,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The Kaplan\u2013Meier analysis showed a significantly higher cumulative incidence in the ADHD group over the 15-year period (Log-rank test\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). ADHD patients with other psychiatric comorbidities had a higher risk of child abuse. Pharmacological treatment of either methylphenidate or atomoxetine was associated with a reduced risk of child abuse. The total adjusted HR was 1.466 (95% CI\u2009=\u20091.077\u20131.883,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) in medicine group compared with the controls.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>ADHD was associated with a subsequent risk of child abuse in Taiwan. Pharmacological treatment could reduce the risk of child abuse in ADHD patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/cap.2023.0003","type":"journal-article","created":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T15:14:13Z","timestamp":1679411653000},"page":"59-68","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Pharmacotherapy May Attenuate the Risk of Child Abuse in Attention-Deficit\/Hyperactivity Disorder from the Real-World Evidence"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3106-6814","authenticated-orcid":false,"given":"Cian-Cian","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Hsiang","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Medical Research, Tri-Service General Hospital, Taipei, Taiwan."},{"name":"School of Public Health, National Defense Medical Center, Taipei, Taiwan."},{"name":"Taiwanese Injury Prevention and Safety Promotion Association, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu-Chien","family":"Chien","sequence":"additional","affiliation":[{"name":"Department of Medical Research, Tri-Service General Hospital, Taipei, Taiwan."},{"name":"School of Public Health, National Defense Medical Center, Taipei, Taiwan."},{"name":"Taiwanese Injury Prevention and Safety Promotion Association, Taipei, Taiwan."},{"name":"Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nian-Sheng","family":"Tzeng","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan."},{"name":"Student Counseling Center, National Defense Medical Center, Taipei, 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