{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:58:48Z","timestamp":1777481928737,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Biotherapy and Radiopharmaceuticals"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:p>\n                    Overexpression of special AT-rich sequence binding protein 1 (SATB1), a global genome organizer, as a predictor of poor prognosis in cutaneous malignant melanoma (CMM) attracted great interest in previous research. In this article, upregulated SATB1 was observed in three melanoma cell lines and in eight CMM tissues. After downregulating SATB1 by RNAi, proliferation of A375 was suppressed\n                    <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                    . In summary, the proliferation of CMM could be related closely to the SATB1 gene. Interference of this gene may be a promising method for CMM therapy.\n                  <\/jats:p>","DOI":"10.1089\/cbr.2013.1502","type":"journal-article","created":{"date-parts":[[2014,1,7]],"date-time":"2014-01-07T08:01:28Z","timestamp":1389081688000},"page":"77-82","source":"Crossref","is-referenced-by-count":8,"title":["Inhibition of SATB1 by shRNA Suppresses the Proliferation of Cutaneous Malignant Melanoma"],"prefix":"10.1177","volume":"29","author":[{"given":"Lei","family":"Zhang","sequence":"first","affiliation":[{"name":"Chinese Academy of Medical Sciences & Peking Union Medical College","place":["China"]},{"name":"Dermatology Hospital of Jiangxi Province","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Cheng","sequence":"additional","affiliation":[{"name":"Xingtai People's Hospital","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Runzhi","family":"He","sequence":"additional","affiliation":[{"name":"Xingtai People's Hospital","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Chen","sequence":"additional","affiliation":[{"name":"Chinese Academy of Medical Sciences & Peking Union Medical College","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Liu","sequence":"additional","affiliation":[{"name":"Chinese Academy of Medical Sciences & Peking Union Medical College","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianfang","family":"Sun","sequence":"additional","affiliation":[{"name":"Chinese Academy of Medical Sciences & Peking Union Medical College","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,3,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2011.08.006"},{"key":"e_1_3_3_3_2","first-page":"488","article-title":"Treatment of metastatic melanoma: An overview","volume":"23","author":"Bhatia S","year":"2009","unstructured":"Bhatia S, , Tykodi SS, , Thompson JA. 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