{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T02:55:49Z","timestamp":1788576949366,"version":"build-2803163510"},"reference-count":181,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cellular Reprogramming"],"published-print":{"date-parts":[[2024,2,1]]},"abstract":"<jats:p>\n                    Aging causes numerous age-related diseases, leading the human species to death. Nevertheless, rejuvenating strategies based on cell epigenetic modifications are a possible approach to counteract disease progression while getting old. Cell reprogramming of adult somatic cells toward pluripotency ought to be a promising tool for age-related diseases. However, researchers do not have control over this process as cells lose their fate, and cause potential cancerous cells or unexpected cell phenotypes. Direct and partial reprogramming were introduced in recent years with distinctive applications. Although direct reprogramming makes cells lose their identity, it has various applications in regeneration medicine. Temporary and regulated\n                    <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                    overexpression of Yamanaka factors has been shown in several experimental contexts to be achievable and is used to rejuvenate mice models. This regeneration can be accomplished by altering the epigenetic adult cell signature to the signature of a younger cell. The greatest advantage of partial reprogramming is that this method does not allow cells to lose their identity when they are resetting their epigenetic clock. It is a regimen of short-term Oct3\/4, Sox2, Klf4, and c-Myc expression\n                    <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                    that prevents full reprogramming to the pluripotent state and avoids both tumorigenesis and the presence of unwanted undifferentiated cells. We know that many neurological age-related diseases, such as Alzheimer's disease, stroke, dementia, and Parkinson's disease, are the main cause of death in the last decades of life. Therefore, scientists have a special tendency regarding neuroregeneration methods to increase human life expectancy.\n                  <\/jats:p>","DOI":"10.1089\/cell.2023.0123","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T11:12:35Z","timestamp":1708513955000},"page":"10-23","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Partial Reprogramming as a Method for Regenerating Neural Tissues in Aged Organisms"],"prefix":"10.1177","volume":"26","author":[{"given":"Ali Saber","family":"Sichani","sequence":"first","affiliation":[{"name":"Department of Biology, Texas A&amp;M University, College Station, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somayeh","family":"Khoddam","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shayan","family":"Shakeri","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Tavakkoli","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arad Ranji","family":"Jafroodi","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Dabbaghipour","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"Sisakht","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8485-9247","authenticated-orcid":false,"given":"Jafar","family":"Fallahi","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,15]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12586"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13714"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2015.07.012"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2020.09.008"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-100818-125127"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/5584_2019_374"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2011.22"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3247"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1615-07.2007"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05913"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2008.12.003"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10040572"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43587-022-00183-2"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glu042"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.08.023"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1672-0229(08)60044-3"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2014.09.013"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00392-1"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2014.05.020"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.11.034"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2021.03.001"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.04.043"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2019.09.003"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13577"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13578"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000602"},{"key":"e_1_3_4_28_1","first-page":"1","author":"Cipriano A","year":"2023","unstructured":"Cipriano A, , Moqri M, , Maybury-Lewis SY, et al. Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming. Nat Aging, 2023:1\u201313.","journal-title":"Nat Aging"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2015.09.002"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.05.035"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.34081"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08085"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.02.008"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(87)90585-X"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2013-14-9-r102"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201707650"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1158799"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1237423"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2164"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13028"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073858413493148"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.08.015"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.202913"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2021.101407"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9112451"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.71624"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-30069-6"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.10.021"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08533"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09195"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3173"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2018.00410"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2017.10.022"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2013.12.001"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(62)90043-X"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2022.140"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(61)90192-6"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1093\/bfgp\/2.3.234"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2014.10.007"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn828"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02185763"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2022.110730"},{"key":"e_1_3_4_63_1","first-page":"163","article-title":"Maps of strength of positional signalling activity in the developing chick wing bud","volume":"87","author":"Honig LS","year":"1985","unstructured":"Honig LS, , Summerbell D. Maps of strength of positional signalling activity in the developing chick wing bud. J Embryol Exp Morphol, 1985; 87:163\u2013174.","journal-title":"J Embryol Exp Morphol"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2013-14-10-r115"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-015-0649-6"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-018-0004-3"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-812215-0.00004-2"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2015.07.006"},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.233221.113"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040028"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fob.2013.08.007"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.304510"},{"key":"e_1_3_4_73_1","doi-asserted-by":"publisher","DOI":"10.1152\/physiolgenomics.00146.2009"},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature23283"},{"key":"e_1_3_4_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.11.026"},{"key":"e_1_3_4_76_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12915-015-0118-4"},{"key":"e_1_3_4_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2021.07.012"},{"key":"e_1_3_4_78_1","doi-asserted-by":"publisher","DOI":"10.1089\/cell.2023.0074"},{"key":"e_1_3_4_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.02.039"},{"key":"e_1_3_4_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2014.056"},{"key":"e_1_3_4_81_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-019-02046-0"},{"key":"e_1_3_4_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2021.09.002"},{"key":"e_1_3_4_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2015.06.003"},{"key":"e_1_3_4_84_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-020-05370-1"},{"key":"e_1_3_4_85_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3975-14.2015"},{"key":"e_1_3_4_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.05.039"},{"key":"e_1_3_4_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2975-4"},{"key":"e_1_3_4_88_1","first-page":"710210","article-title":"Reversal of ageing-and injury-induced vision loss by Tet-dependent epigenetic reprogramming","volume":"2019","author":"Lu Y","year":"2019","unstructured":"Lu Y, , Krishnan A, , Brommer B, et al. Reversal of ageing-and injury-induced vision loss by Tet-dependent epigenetic reprogramming. BioRxiv, 2019; 2019:710210.","journal-title":"BioRxiv"},{"key":"e_1_3_4_89_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43587-023-00527-6"},{"key":"e_1_3_4_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41421-021-00243-8"},{"key":"e_1_3_4_91_1","doi-asserted-by":"publisher","DOI":"10.1089\/cell.2023.0072"},{"key":"e_1_3_4_92_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1205526109"},{"key":"e_1_3_4_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2011.09.002"},{"key":"e_1_3_4_94_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.11-1102.ufm"},{"key":"e_1_3_4_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2019.08.009"},{"key":"e_1_3_4_96_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3270"},{"key":"e_1_3_4_97_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glaa286"},{"key":"e_1_3_4_98_1","doi-asserted-by":"publisher","DOI":"10.1089\/rej.2017.1958"},{"key":"e_1_3_4_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2015.09.001"},{"key":"e_1_3_4_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00393-3"},{"key":"e_1_3_4_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1554"},{"key":"e_1_3_4_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2017.11.010"},{"key":"e_1_3_4_103_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.138263"},{"key":"e_1_3_4_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2561"},{"key":"e_1_3_4_105_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-020-0696-0"},{"key":"e_1_3_4_106_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb0511-490"},{"key":"e_1_3_4_107_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2011.00785.x"},{"key":"e_1_3_4_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2018.05.011"},{"key":"e_1_3_4_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2015.03.006"},{"key":"e_1_3_4_110_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2843"},{"key":"e_1_3_4_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.11.052"},{"key":"e_1_3_4_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.01.005"},{"key":"e_1_3_4_113_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.256149"},{"key":"e_1_3_4_114_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12877"},{"key":"e_1_3_4_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-5193(73)90198-7"},{"key":"e_1_3_4_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1897"},{"key":"e_1_3_4_117_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43587-023-00528-5"},{"issue":"1","key":"e_1_3_4_118_1","first-page":"7","article-title":"Generation of neural cells by direct cellular reprogramming","volume":"1","author":"Pawlowski M","year":"2013","unstructured":"Pawlowski M, , Kotter M. Generation of neural cells by direct cellular reprogramming. J Transplant Stem Cell Biol, 2013; 1(1):7.","journal-title":"J Transplant Stem Cell Biol"},{"key":"e_1_3_4_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2017.07.023"},{"key":"e_1_3_4_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2004.07.007"},{"key":"e_1_3_4_121_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.091355"},{"key":"e_1_3_4_122_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1007466"},{"key":"e_1_3_4_123_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2388-4"},{"key":"e_1_3_4_124_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11044"},{"key":"e_1_3_4_125_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1072530"},{"key":"e_1_3_4_126_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2022.12861"},{"key":"e_1_3_4_127_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2660"},{"key":"e_1_3_4_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cels.2022.05.002"},{"key":"e_1_3_4_129_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm11111050"},{"key":"e_1_3_4_130_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15174-3"},{"key":"e_1_3_4_131_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.204248"},{"key":"e_1_3_4_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2013.12.050"},{"key":"e_1_3_4_133_1","doi-asserted-by":"publisher","DOI":"10.2174\/156652312800099616"},{"key":"e_1_3_4_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.07.039"},{"key":"e_1_3_4_135_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-021-01158-7"},{"key":"e_1_3_4_136_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12038-019-9923-1"},{"key":"e_1_3_4_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2011.07.014"},{"key":"e_1_3_4_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2016.01.010"},{"key":"e_1_3_4_139_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11139"},{"key":"e_1_3_4_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2015.11.003"},{"issue":"1","key":"e_1_3_4_141_1","first-page":"5","article-title":"Critical factors for cardiac reprogramming","volume":"111","author":"Srivastava D","year":"2012","unstructured":"Srivastava D, , Ieda M. Critical factors for cardiac reprogramming. Am Heart Assoc, 2012; 111(1):5\u20138.","journal-title":"Am Heart Assoc"},{"key":"e_1_3_4_142_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4338"},{"key":"e_1_3_4_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2022.01.029"},{"key":"e_1_3_4_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2021.02.009"},{"key":"e_1_3_4_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.11.019"},{"key":"e_1_3_4_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.07.024"},{"key":"e_1_3_4_147_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-018-0888-0"},{"key":"e_1_3_4_148_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.058655"},{"key":"e_1_3_4_149_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08894"},{"key":"e_1_3_4_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.06.040"},{"key":"e_1_3_4_151_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1303829110"},{"key":"e_1_3_4_152_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.20540"},{"issue":"4","key":"e_1_3_4_153_1","first-page":"631","article-title":"The role of mammalian DNA methyltransferases in the regulation of gene expression","volume":"10","author":"Turek-Plewa J","year":"2005","unstructured":"Turek-Plewa J, , Jagodzi\u0144ski PP. The role of mammalian DNA methyltransferases in the regulation of gene expression. Cell Mol Biol Lett, 2005; 10(4):631\u2013647.","journal-title":"Cell Mol Biol Lett"},{"key":"e_1_3_4_154_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1510595112"},{"key":"e_1_3_4_155_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08797"},{"key":"e_1_3_4_156_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23353-z"},{"key":"e_1_3_4_157_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-009-9231-5"},{"key":"e_1_3_4_158_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-021-00335-z"},{"key":"e_1_3_4_159_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.799152"},{"key":"e_1_3_4_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2019.07.015"},{"key":"e_1_3_4_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2022.104596"},{"key":"e_1_3_4_162_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2016.07.026"},{"key":"e_1_3_4_163_1","doi-asserted-by":"publisher","DOI":"10.1038\/newbio239197a0"},{"key":"e_1_3_4_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2012.10.013"},{"key":"e_1_3_4_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(02)00835-8"},{"key":"e_1_3_4_166_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2010.00624.x"},{"issue":"1","key":"e_1_3_4_167_1","first-page":"1","article-title":"Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington's disease","volume":"11","author":"Wu Z","year":"2020","unstructured":"Wu Z, , Parry M, , Hou X-Y, et al. Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington's disease. Nat Commun, 2020; 11(1):1\u201318.","journal-title":"Nat Commun"},{"key":"e_1_3_4_168_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-020-01584-0"},{"key":"e_1_3_4_169_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-53007-6"},{"key":"e_1_3_4_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2015.01.013"},{"key":"e_1_3_4_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.12.027"},{"key":"e_1_3_4_172_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202001657RR"},{"key":"e_1_3_4_173_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0425-3"},{"key":"e_1_3_4_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2014.11.001"},{"key":"e_1_3_4_175_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10323"},{"key":"e_1_3_4_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2015.09.012"},{"key":"e_1_3_4_177_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-019-0204-5"},{"key":"e_1_3_4_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0047-6374(02)00014-3"},{"key":"e_1_3_4_179_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2021.05.020"},{"key":"e_1_3_4_180_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07314"},{"key":"e_1_3_4_181_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.201"},{"key":"e_1_3_4_182_1","doi-asserted-by":"publisher","DOI":"10.1089\/scd.2017.0250"}],"container-title":["Cellular Reprogramming"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/cell.2023.0123","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/cell.2023.0123","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/cell.2023.0123","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:38:26Z","timestamp":1777390706000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/cell.2023.0123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,1]]},"references-count":181,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,2,1]]}},"alternative-id":["10.1089\/cell.2023.0123"],"URL":"https:\/\/doi.org\/10.1089\/cell.2023.0123","relation":{},"ISSN":["2152-4971","2152-4998"],"issn-type":[{"value":"2152-4971","type":"print"},{"value":"2152-4998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,1]]}}}