{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T01:46:03Z","timestamp":1793238363562,"version":"4.5.0"},"reference-count":53,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dermatitis\u00ae"],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Abstract: Background\/Objectives:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    The aim of our study was to investigate the effectiveness of personalized training on skin protection associated with the regular use of ceramide-containing cream (CC) versus other creams (OC) for improving hand contact dermatitis.\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:underline>Methods:<\/jats:underline>\n                    <\/jats:title>\n                    <jats:p>We performed a double-center randomized trial that enrolled workers with hand dermatitis. All workers received personalized training. The intervention was 3 times per day application of the study emollient. The control arm used an emollient of choice without ceramide, as needed. The primary outcome was improvement in hand dermatitis at 1 and 3 months of follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:underline>Results:<\/jats:underline>\n                    <\/jats:title>\n                    <jats:p>In total, 102 patients with hand dermatitis were enrolled in this study. Improvement in dermatitis was found in 40%, 52.5%, 50%, and 63% of OC and CC, at the first and second follow-ups, respectively. The use of CC was significantly associated with an improvement in dermatitis (odds ratios 2.6; 95% confidence intervals 1.30\u20135.2), analyzed using generalized equation estimation during the follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:underline>Conclusion:<\/jats:underline>\n                    <\/jats:title>\n                    <jats:p>Our study demonstrated that an educational personalized intervention could improve the signs and symptoms in patients with hand dermatitis, and the use of a CC resulted in a significantly better outcome during the 3 months of follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/derm.2022.29002.flf","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T11:44:40Z","timestamp":1679312680000},"page":"127-134","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Effectiveness of a Skin Care Program with a Cream Containing Ceramide C and a Personalized Training for Secondary Prevention of Hand Contact Dermatitis"],"prefix":"10.1177","volume":"34","author":[{"given":"Francesca","family":"Larese Filon","sequence":"first","affiliation":[{"name":"From the *Unit of Occupational Medicine, University of Trieste, Trieste, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Maculan","sequence":"additional","affiliation":[{"name":"Unit of Occupational Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Angiola","family":"Crivellaro","sequence":"additional","affiliation":[{"name":"Unit of Occupational Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcella","family":"Mauro","sequence":"additional","affiliation":[{"name":"From the *Unit of Occupational Medicine, University of Trieste, Trieste, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,3,16]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2000.043002065.x"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-002-0418-1"},{"key":"e_1_3_1_4_2","first-page":"Doc07","article-title":"Occupational skin diseases: options for multidisciplinary networking in preventive medicine","volume":"6","author":"Jhon SM.","year":"2008","unstructured":"Jhon SM. 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A daily regimen of a ceramide-dominant moisturizing cream and cleanser restores the skin permeability barrier in adults with moderate eczema: a randomized trial. Dermatol Ther, 2021; 34(4):e14970.","journal-title":"Dermatol Ther"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.2020.4796"},{"issue":"9","key":"e_1_3_1_18_2","first-page":"1024","article-title":"Atopic dermatitis, the role for a ceramide-dominant, physiologic lipid-based barrier repair emulsion","volume":"12","author":"Kircik L","year":"2013","unstructured":"Kircik L, , Hougeir F, , Biski J. Atopic dermatitis, the role for a ceramide-dominant, physiologic lipid-based barrier repair emulsion. 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