{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:24:49Z","timestamp":1792761889625,"version":"4.5.0"},"reference-count":54,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dermatitis\u00ae"],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Abstract: Background:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    Patch testing is an important diagnostic tool for assessment of allergic contact dermatitis (ACD).\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:underline>Objective:<\/jats:underline>\n                    <\/jats:title>\n                    <jats:p>This study documents the North American Contact Dermatitis Group (NACDG) patch testing results from January 1, 2019, to December 31, 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:underline>Methods:<\/jats:underline>\n                    <\/jats:title>\n                    <jats:p>At 13 centers in North America, patients were tested in a standardized manner with a screening series of 80 allergens, and, as indicated, supplemental allergens.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:underline>Results:<\/jats:underline>\n                    <\/jats:title>\n                    <jats:p>Overall, 4121 patients were tested; 2871 (69.7%) had at least 1 positive\/allergic patch test reaction and 2095 patients (51.2%) had a primary diagnosis of ACD. The most commonly positive allergens were nickel (18.2%), methylisothiazolinone (MI) (13.8%), fragrance mix (FM) I (12.8%), hydroperoxides of linalool (HPL) (11.1%), and benzisothiazolinone (BIT) (10.4%). Compared with that of 2017\u20132018, prevalence of top 20 allergens statistically increased for FM I, HPL, BIT, propolis, and hydroperoxides of limonene (3.5%). For the first time, MI positivity did not increase between reporting periods. Approximately one-fifth of patients (20.3%) had \u22651 clinically relevant reaction(s) to allergens\/substances not on the NACDG series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:underline>Conclusions:<\/jats:underline>\n                    <\/jats:title>\n                    <jats:p>The epidemic of MI contact allergy in North America may have reached a plateau. Patch testing using a robust screening series, and supplemental allergens as indicated, is necessary for comprehensive evaluation of ACD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/derm.2022.29017.jdk","type":"journal-article","created":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T10:49:56Z","timestamp":1674730196000},"page":"90-104","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":130,"title":["North American Contact Dermatitis Group Patch Test Results: 2019\u20132020"],"prefix":"10.1177","volume":"34","author":[{"given":"Joel G.","family":"DeKoven","sequence":"first","affiliation":[{"name":"From the *Division of Dermatology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada;"},{"name":"Division of Occupational Health, Unity Health Toronto, St. Michael's Hospital, Toronto, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin 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