{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T05:09:35Z","timestamp":1784005775014,"version":"3.55.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T00:00:00Z","timestamp":1694736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dermatitis\u00ae"],"published-print":{"date-parts":[[2023,10,1]]},"abstract":"<jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Background:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    Although allergic contact dermatitis (ACD) is relatively common in the adult and pediatric populations alike, few studies describe the special features of contact sensitization among the Israeli pediatric populations, none of them is multicenter. Our study aims to describe and analyze patch test results and trends in 4 tertiary care centers between 2012 and 2022.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Methods:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    We assessed the results of 357 patch tests performed on children 0\u201318 years old between 2012 and 2022 in designated clinics in 4 tertiary medical centers. All patients were tested using the European baseline series and additional series as clinically indicated. We assessed the demographic features, atopic features, and influence, as well as the main allergens to cause sensitization and allergic contact dermatitis among the pediatric population.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    In total 69% of the study population were females, mainly 12\u201318 years old, 35% of the study population were previously diagnosed with atopic dermatitis, and 57% had an atopic diathesis. Females were more commonly sensitized (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u20090.05). Patients without atopic dermatitis were more commonly diagnosed with ACD and had more reactions on patch test (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u20090.05). The most common allergens to cause ACD are preservatives and metals, as previously described, however, acrylate sensitivity is an emerging group that has not been described among the Israeli pediatric population in previous studies. Fragrance mix 2 and Mroxylon pereirae are relatively rare allergens among the Israeli pediatric population, whereas linalool hyperoxide might be considered an emerging allergen. Methylisothiazolinone causes ACD more frequently among patients without atopic dermatitis (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u20090.05).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    Among the Israeli pediatric population, ACD is more common in females without atopic dermatitis. Acrylates become a common culprit and should be included in baseline series. Patients with atopic dermatitis are less frequently sensitized by methylisothiazolinone.\n                  <\/jats:p>","DOI":"10.1089\/derm.2023.0009","type":"journal-article","created":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T16:22:17Z","timestamp":1684254137000},"page":"399-404","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Pediatric Contact Dermatitis: A 10-Year Multicenter Retrospective Study"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8852-9384","authenticated-orcid":false,"given":"Dan","family":"Slodownik","sequence":"first","affiliation":[{"name":"From the,  Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel;"},{"name":"Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6560-2625","authenticated-orcid":false,"given":"Jonathan","family":"Bar","sequence":"additional","affiliation":[{"name":"From the,  Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel;"},{"name":"Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Solomon","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Chaim Sheba Medical Center, Tel Hashomer, Israel;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaron","family":"Lavy","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Chaim Sheba Medical Center, Tel Hashomer, Israel;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Baum","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Chaim Sheba Medical Center, Tel Hashomer, Israel;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orel","family":"Mordechai Galed","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Chaim Sheba Medical Center, Tel Hashomer, Israel;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roten","family":"Cnaan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Chaim Sheba Medical Center, Tel Hashomer, Israel;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efrat","family":"Solomon-Cohen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Rabin Medical Center, Petah-Tiqva, Israel;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liran","family":"Horev","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hadassah University Medical Center, Jerusalem, Israel; and"},{"name":"Shamir Medical Center, Zerifin, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny","family":"Daniely","sequence":"additional","affiliation":[{"name":"From the,  Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel;"},{"name":"Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,9,15]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1999.tb06102.x"},{"issue":"6","key":"e_1_3_1_3_2","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1080\/1744666X.2020.1777858","article-title":"Allergic contact dermatitis in children","volume":"16","author":"Belloni Fortina A","year":"2020","unstructured":"Belloni Fortina A, , Caroppo F, , Tadiotto Cicogna G. 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