{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T16:44:37Z","timestamp":1782924277569,"version":"3.54.5"},"reference-count":17,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:00:00Z","timestamp":1710374400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dermatitis\u00ae"],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Abstract: Background:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    Propylene glycol (PG) and butylene glycol (BG) are not known to be cross-reactors. However, no large-scale studies have assessed the cross-reactivity rate (CRR) between these 2 structurally and functionally similar compounds.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Objectives<\/jats:italic>\n                      <\/jats:bold>\n                      <jats:italic toggle=\"yes\">:<\/jats:italic>\n                    <\/jats:underline>\n                    The aim of this study was to determine whether PG and BG demonstrate cross-reactivity.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Methods:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    This is a retrospective chart review of 893 patients who underwent patch testing for both PG and BG from 2020 to 2022. The frequencies of positive reactions and concomitant reaction rates were calculated.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    In our cohort, 53 (5.94%) patients reacted to PG and 13 patients (1.46%) reacted to BG. Of the patients who reacted to PG, 6 reacted to BG representing a CRR of 11.3%, whereas the CRR to PG in BG-allergic patients was 46.2%.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    For those allergic to BG, PG should be considered a cross-reactor. This relationship is somewhat unidirectional, as patients allergic to PG demonstrated a CRR to BG of only 11.3%, significantly lower than the 46.2% CRR to PG among BG-allergic patients.\n                  <\/jats:p>","DOI":"10.1089\/derm.2023.0143","type":"journal-article","created":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T14:38:22Z","timestamp":1692283102000},"page":"149-151","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Cross-Reactivity between Propylene Glycol and Butylene Glycol"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2418-3537","authenticated-orcid":false,"given":"Samuel F.","family":"Ekstein","sequence":"first","affiliation":[{"name":"From the,  Department of Dermatology, Park Nicollet Health Services, Minneapolis, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9301-9138","authenticated-orcid":false,"given":"Nicholas","family":"Battis","sequence":"additional","affiliation":[{"name":"From the,  Department of Dermatology, Park Nicollet Health Services, Minneapolis, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1274-232X","authenticated-orcid":false,"given":"Dominick","family":"Dabrowski","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Medicine, HealthPartners Medical Group, Minneapolis, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne B.","family":"Neeley","sequence":"additional","affiliation":[{"name":"From the,  Department of Dermatology, Park Nicollet Health Services, Minneapolis, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,3,14]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2008.08039"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000307"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.2310\/6620.2008.07037"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1994.tb01995.x"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000315"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2005.00693.x"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.11.033"},{"issue":"4","key":"e_1_3_1_9_2","first-page":"234","article-title":"Allergic contact dermatitis due to 1,3-butylene glycol","volume":"43","author":"Diegenant C","year":"2000","unstructured":"Diegenant C, , Constandt L, , Goossens A. Allergic contact dermatitis due to 1,3-butylene glycol. Contact Dermatitis. 2000; 43(4):234\u2013235.","journal-title":"Contact Dermatitis"},{"issue":"1","key":"e_1_3_1_10_2","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/cod.14115","article-title":"Occupational allergic contact dermatitis caused by tetrahydroxypropyl ethylenediamine in hand disinfectants","volume":"87","author":"Blomberg M","year":"2022","unstructured":"Blomberg M, , J\u00f8rgensen CCL, , Bregnh\u00f8j A, et al. Occupational allergic contact dermatitis caused by tetrahydroxypropyl ethylenediamine in hand disinfectants. Contact Dermatitis. 2022; 87(1):114\u2013116.","journal-title":"Contact Dermatitis"},{"key":"e_1_3_1_11_2","first-page":"195","article-title":"Group study on contact sensitivity of 1,3-butylene glycol","volume":"4","author":"Matsunaga K","year":"1997","unstructured":"Matsunaga K, , Sugai T, , Katoh J, et al. Group study on contact sensitivity of 1,3-butylene glycol. Environ Dermatol. 1997; 4:195\u2013201.","journal-title":"Environ Dermatol"},{"key":"e_1_3_1_12_2","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1600-0536.1997.tb00046.x","article-title":"Contact dermatitis due to 1,3-butylene glycol","volume":"37","author":"Sugiura M","year":"1997","unstructured":"Sugiura M, , Hayakawa R. Contact dermatitis due to 1,3-butylene glycol. Contact Dermatitis. 1997; 37:90.","journal-title":"Contact Dermatitis"},{"key":"e_1_3_1_13_2","unstructured":"PubChem [Database Online]. National Center for Biotechnology Information. Updated 2023. https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Propylene-Glycol [Last accessed: March 1 2023]."},{"key":"e_1_3_1_14_2","unstructured":"PubChem [database online]. National Center for Biotechnology Information. Updated 2023. https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/7896 [Last accessed: March 1 2023]."},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.2.272"},{"key":"e_1_3_1_16_2","first-page":"203","article-title":"Patch testing by additional series of allergens: results of further experiences","volume":"12","author":"Francalanci S","year":"2001","unstructured":"Francalanci S, , Giorgini S, , Ricci L, et al. Patch testing by additional series of allergens: results of further experiences. Am J Contact Dermatitis. 2001; 12:203\u2013207.","journal-title":"Am J Contact Dermatitis"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000254"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13581"}],"container-title":["Dermatitis\u00ae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/derm.2023.0143","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/derm.2023.0143","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/derm.2023.0143","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:08:32Z","timestamp":1777399712000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/derm.2023.0143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,14]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,4,1]]}},"alternative-id":["10.1089\/derm.2023.0143"],"URL":"https:\/\/doi.org\/10.1089\/derm.2023.0143","relation":{},"ISSN":["1710-3568","2162-5220"],"issn-type":[{"value":"1710-3568","type":"print"},{"value":"2162-5220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,14]]}}}