{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:24:49Z","timestamp":1792761889956,"version":"4.5.0"},"reference-count":5,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dermatitis\u00ae"],"published-print":{"date-parts":[[2024,6,1]]},"abstract":"\n Abstract:<\/jats:underline>\n <\/jats:title>\n \n \n \n Background:<\/jats:italic>\n <\/jats:bold>\n <\/jats:underline>\n Although most patients do not develop hypersensitivity reactions to metals in implanted devices, when they do occur, significant morbidity can result. Titanium-based systems are often considered as an alternative option in metal-allergic patients; however, there are few studies published on titanium allergy and allergic reactions to titanium in implants may be overlooked in clinical practice.\n <\/jats:p>\n \n \n \n Methods:<\/jats:italic>\n <\/jats:bold>\n <\/jats:underline>\n Our aim was to further characterize a single institution's experience with titanium patch testing and evaluation of titanium allergy. We performed a retrospective medical record review of 166 patients evaluated for titanium contact allergy between January 2018-August 2023. Of the 166 patients in our cohort, 67 were referred for pre-implant patch testing and 64 for post-implant patch testing; 35 were tested for reasons unrelated to an implant.\n <\/jats:p>\n \n \n \n Results:<\/jats:italic>\n <\/jats:bold>\n <\/jats:underline>\n Twenty-six of the 166 patients were PTP to titanium (15.7% positive rate). Titanium PTP rates were higher for post-implant cases (28.1%, 18\/64) compared to pre-implant cases (6.0%, 4\/67) (\u03c7\n 2<\/jats:sup>\n 9.97,\n p<\/jats:italic>\n \u2009=\u20090.002). Among 18 titanium PTPs identified for the 64 post-implant cases, 8 were likely relevant, 8 possibly relevant, and 2 not likely relevant.\n <\/jats:p>\n \n \n \n Conclusions:<\/jats:italic>\n <\/jats:bold>\n <\/jats:underline>\n Further studies should be performed to evaluate the incidence of allergy to titanium implants and to continue surveillance of changes in sensitization rates.\n <\/jats:p>","DOI":"10.1089\/derm.2023.0282","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T11:21:56Z","timestamp":1704712916000},"page":"242-245","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Titanium Allergy: A Retrospective Review of 166 Patch Tested Patients"],"prefix":"10.1177","volume":"35","author":[{"given":"Camila N. Fontane","family":"Hoyos","sequence":"first","affiliation":[{"name":"From the, Brigham and Women's Hospital, Boston, Massachusetts, USA;"},{"name":"Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia F.","family":"Chen","sequence":"additional","affiliation":[{"name":"From the, Brigham and Women's Hospital, Boston, Massachusetts, USA;"},{"name":"Department of Orthopaedics, Brigham and Women's Hospital, Boston, MA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari M.","family":"Goldminz","sequence":"additional","affiliation":[{"name":"From the, Brigham and Women's Hospital, Boston, Massachusetts, USA;"},{"name":"Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,6,21]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000091"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13010"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000609"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000210"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12565"}],"container-title":["Dermatitis\u00ae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/derm.2023.0282","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/derm.2023.0282","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/derm.2023.0282","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:08:37Z","timestamp":1777399717000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/derm.2023.0282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,1]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6,1]]}},"alternative-id":["10.1089\/derm.2023.0282"],"URL":"https:\/\/doi.org\/10.1089\/derm.2023.0282","relation":{},"ISSN":["1710-3568","2162-5220"],"issn-type":[{"value":"1710-3568","type":"print"},{"value":"2162-5220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,1]]}}}