{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T11:44:42Z","timestamp":1785498282295,"version":"3.56.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dermatitis\u00ae"],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"<jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Abstract: Background:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    Recent evidence shows similar rates of allergic contact Dermatitis\u00ae (ACD) among children and adults despite children accounting for less than 10% of patch testing subjects. With a need for in-depth analyses of pediatric ACD, we herein characterize a pediatric cohort at a large North American patch testing center.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Methods:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    A retrospective chart review was conducted for 135 patients ages 1\u201317 years who underwent patch testing from July 2020 from August 2023. Data were stratified by age 1\u20135, 6\u201311, and 12\u201317 years. Significance-Prevalence Index Numbers (SPIN) were calculated.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    A total of 86% were sensitized, 40% had a relevant reaction, and positivity rates were equal between males and females. Top allergens by SPIN differed with age, but overall were linalool hydroperoxides (SPIN = 11.01), propylene glycol (10.30), limonene hydroperoxides (10.27), fragrance mix I (5.62), and lanolin (4.90). In total, 14% of the top allergens were not represented on the North American Contact Dermatitis\u00ae Group standard series. Of those tested to personal products, 45% had positive reactions and 72% of which were relevant.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                      <\/jats:bold>\n                    <\/jats:underline>\n                    Emulsifiers and fragrances were the most relevant allergen categories, with the impact of emulsifiers not previously reported. ACD may affect males and females equally in this population. Supplemental allergens and personal products tested \u201cas-is\u201d contribute to conclusive pediatric patch testing.\n                  <\/jats:p>","DOI":"10.1089\/derm.2024.0005","type":"journal-article","created":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T11:17:31Z","timestamp":1719227851000},"page":"618-624","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Characterization of Pediatric Patch Testing: A Retrospective Review, 2020\u20132023"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9118-1849","authenticated-orcid":false,"given":"Caroline","family":"Brumley","sequence":"first","affiliation":[{"name":"From the,  Department of Dermatology, Park Nicollet Health Services, Minneapolis, Minnesota, USA"},{"name":"University of Minnesota Medical School, Minneapolis, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8367-761X","authenticated-orcid":false,"given":"Puneet","family":"Arora","sequence":"additional","affiliation":[{"name":"From the,  Department of Dermatology, Park Nicollet Health Services, Minneapolis, Minnesota, USA"},{"name":"University of Minnesota Medical School, Minneapolis, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara A.","family":"Hylwa","sequence":"additional","affiliation":[{"name":"From the,  Department of Dermatology, Park Nicollet Health Services, Minneapolis, Minnesota, USA"},{"name":"Department of Dermatology, Hennepin Healthcare, Minneapolis, Minnesota, USA"},{"name":"Department of Dermatology, University of Minnesota, Minneapolis, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,11,25]]},"reference":[{"issue":"1","key":"e_1_3_1_2_2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.mcna.2019.08.012","article-title":"Allergic Contact Dermatitis\u00ae","volume":"104","author":"Nassau S","year":"2020","unstructured":"Nassau S, , Fonacier L. Allergic Contact Dermatitis\u00ae. Med Clin North Am. 2020; 104(1):61\u201376; doi: 10.1016\/j.mcna.2019.08.012","journal-title":"Med Clin North Am"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2005.05014.x"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000083"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13119"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.11.002"},{"issue":"4","key":"e_1_3_1_7_2","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.jaad.2021.07.030","article-title":"Age-related differences in patch testing results among children: Analysis of north american contact Dermatitis\u00ae group data, 2001-2018","volume":"86","author":"Silverberg JI","year":"2022","unstructured":"Silverberg JI, , Hou A, , Warshaw EM, et al. Age-related differences in patch testing results among children: Analysis of north american contact Dermatitis\u00ae group data, 2001-2018. J Am Acad Dermatol. 2022; 86(4):818\u2013826; doi: 10.1016\/j.jaad.2021.07.030","journal-title":"J Am Acad Dermatol"},{"issue":"10","key":"e_1_3_1_8_2","first-page":"1329","article-title":"Contact allergy in children referred for patch testing: North american contact Dermatitis\u00ae group data, 2001-2004","volume":"144","author":"Zug KA","year":"2008","unstructured":"Zug KA, , McGinley-Smith D, , Warshaw EM, et al. Contact allergy in children referred for patch testing: North american contact Dermatitis\u00ae group data, 2001-2004. Arch Dermatol. 2008; 144(10):1329\u20131336.","journal-title":"Arch Dermatol"},{"issue":"5","key":"e_1_3_1_9_2","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1016\/j.jaad.2023.01.016","article-title":"Pediatric allergic contact Dermatitis\u00ae registry patch testing results from 2016 to 2022: A retrospective study of age-related differences","volume":"88","author":"Young K","year":"2023","unstructured":"Young K, , Collis RW, , Sheinbein D, et al. Pediatric allergic contact Dermatitis\u00ae registry patch testing results from 2016 to 2022: A retrospective study of age-related differences. J Am Acad Dermatol. 2023; 88(5):1218\u20131220; doi: 10.1016\/j.jaad.2023.01.016","journal-title":"J Am Acad Dermatol"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/derm.2023.0009"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000214"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000307"},{"issue":"4","key":"e_1_3_1_13_2","first-page":"573","article-title":"Significance-prevalence index number: A reinterpretation and enhancement of data from the North American Contact Dermatitis\u00ae Group","volume":"41","author":"Maouad M","year":"1999","unstructured":"Maouad M, , Fleischer AB, , Sherertz EF, et al. Significance-prevalence index number: A reinterpretation and enhancement of data from the North American Contact Dermatitis\u00ae Group. J Am Acad Dermatol. 1999; 41(4):573\u2013576.","journal-title":"J Am Acad Dermatol"},{"issue":"6","key":"e_1_3_1_14_2","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.anai.2016.09.445","article-title":"Pediatric patch testing: A 10-year retrospective Study","volume":"117","author":"Ascha M","year":"2016","unstructured":"Ascha M, , Irfan M, , Bena J, et al. Pediatric patch testing: A 10-year retrospective Study. Ann Allergy Asthma Immunol., 2016; 117(6):661\u2013667; doi: 10.1016\/j.anai.2016.09.445","journal-title":"Ann Allergy Asthma Immunol."},{"issue":"8","key":"e_1_3_1_15_2","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1001\/jamadermatol.2016.6136","article-title":"Pediatric contact Dermatitis\u00ae registry data on contact allergy in children with atopic Dermatitis\u00ae","volume":"153","author":"Jacob SE","year":"2017","unstructured":"Jacob SE, , McGowan M, , Silverberg NB, et al. Pediatric contact Dermatitis\u00ae registry data on contact allergy in children with atopic Dermatitis\u00ae. JAMA Dermatol., 2017; 153(8):765\u2013770; doi: 10.1001\/jamadermatol.2016.6136","journal-title":"JAMA Dermatol."},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/pai.12397"},{"issue":"1","key":"e_1_3_1_17_2","first-page":"1","article-title":"2-Hydroxyethyl methacrylate (HEMA): A clinical review of contact allergy and allergic contact Dermatitis\u00ae. Part 2. Cross- and co-sensitization, other skin reactions to HEMA, position of HEMA among (meth)acrylates, sensitivity as screening agent, presence of HEMA in commercial products and practical information on patch test procedures","volume":"90","author":"de Groot AC","year":"2023","unstructured":"de Groot AC, , Rustemeyer T. 2-Hydroxyethyl methacrylate (HEMA): A clinical review of contact allergy and allergic contact Dermatitis\u00ae. Part 2. Cross- and co-sensitization, other skin reactions to HEMA, position of HEMA among (meth)acrylates, sensitivity as screening agent, presence of HEMA in commercial products and practical information on patch test procedures. Contact Dermatitis\u00ae. 2023; 90(1):1\u201316; doi: 10.1111\/cod.14430","journal-title":"Contact Dermatitis\u00ae"},{"key":"e_1_3_1_18_2","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.2147\/CCID.S410910","article-title":"Quaternary ammonium compounds and contact Dermatitis\u00ae: A review and considerations during the COVID-19 pandemic","volume":"16","author":"Okeke CAV","year":"2023","unstructured":"Okeke CAV, , Khanna R, , Ehrlich A. Quaternary ammonium compounds and contact Dermatitis\u00ae: A review and considerations during the COVID-19 pandemic. Clin Cosmet Investig Dermatol. 2023; 16:1721\u20131728; doi: 10.2147\/CCID.S410910","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"e_1_3_1_19_2","doi-asserted-by":"crossref","DOI":"10.1111\/ijd.17103","article-title":"Examining the benefits of extended patch test series in children: A comprehensive analysis","author":"Andre N","year":"2024","unstructured":"Andre N, , Usher A, , Ofri M, et al. Examining the benefits of extended patch test series in children: A comprehensive analysis. Int J Dermatol. 2024; doi: 10.1111\/ijd.17103","journal-title":"Int J Dermatol"},{"key":"e_1_3_1_20_2","unstructured":"T.R.U.E. Test: Thin layer rapid use epicutaneous patch test [SmartPractice]. Available from: https:\/\/www.smartpractice.com [Last accessed: December12 2023]."}],"container-title":["Dermatitis\u00ae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/derm.2024.0005","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/derm.2024.0005","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/derm.2024.0005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:08:49Z","timestamp":1777399729000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/derm.2024.0005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,1]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11,1]]}},"alternative-id":["10.1089\/derm.2024.0005"],"URL":"https:\/\/doi.org\/10.1089\/derm.2024.0005","relation":{},"ISSN":["1710-3568","2162-5220"],"issn-type":[{"value":"1710-3568","type":"print"},{"value":"2162-5220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,1]]}}}