{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T05:14:06Z","timestamp":1782450846315,"version":"3.54.5"},"reference-count":15,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,5,29]],"date-time":"2020-05-29T00:00:00Z","timestamp":1590710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Technology &amp; Therapeutics"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>To limit the spread of coronavirus disease 2019 (COVID-19), governments have ordered a series of restrictions that may affect glycemic control in individuals with type 1 diabetes mellitus (T1DM), since physical activity (PA) was not allowed outside home.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We retrospectively evaluated glycemic control of individuals with T1DM using hybrid closed loop (HCL) system in the period before the SARS-CoV-2 outbreak in Italy (February 10\u201323, 2020\u2013Time 1), when movements were only reduced (February 24\u2013March 8, 2020\u2013Time 2) and during complete lockdown (March 9\u201322, 2020\u2013Time 3). Information about regular PA (at least 3\u2009h per week) prior and during the quarantine was collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The study included 13 individuals with a median age of 14.2 years and a good glycemic control at baseline (glucose management indicator of 7%, time in range [TIR] of 68%, time below range [TBR] of 2%). All individuals continued to show good glycemic control throughout the study period. There was an increase in TIR during the study period (+3%) and TIR was significantly higher during Time 3 (72%) than during Time 2 (66%). TBR was significantly lower during Time 3 (1%) both compared with Time 1 and Time 2 (2%). A meaningful variance in TIR at Time 3 between individuals who performed or not PA during quarantine and a significant increase in TIR between Time 2 and Time 3 in individuals both doing PA at baseline and during quarantine was found. At logistic regression, only the presence of PA during quarantine significantly predicted a TIR &gt;70%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Glycemic control of T1DM in adolescents using HCL system did not worsen during the restrictions due to COVID-19 pandemics and further improved in those who continued PA during the quarantine. Maintaining regular PA in a safe home environment is an essential strategy for young individuals with T1DM during the COVID-19 crisis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/dia.2020.0169","type":"journal-article","created":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T14:22:33Z","timestamp":1589811753000},"page":"462-467","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":133,"title":["Glycemic Control in Type 1 Diabetes Mellitus During COVID-19 Quarantine and the Role of In-Home Physical Activity"],"prefix":"10.1177","volume":"22","author":[{"given":"Gianluca","family":"Tornese","sequence":"first","affiliation":[{"name":"Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viola","family":"Ceconi","sequence":"additional","affiliation":[{"name":"University of Trieste, Trieste, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Monasta","sequence":"additional","affiliation":[{"name":"Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Carletti","sequence":"additional","affiliation":[{"name":"Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Faleschini","sequence":"additional","affiliation":[{"name":"Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Egidio","family":"Barbi","sequence":"additional","affiliation":[{"name":"Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy."},{"name":"University of Trieste, Trieste, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,5,29]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30079-5"},{"key":"e_1_3_5_4_2","unstructured":"Coronavirus infection (COVID-19)\u2014II ISPAD Summary 2020. https:\/\/www.ispad.org\/page\/CoronavirusinfectionCOVID-19-IIISPADSummary (accessed March31 2020)."},{"key":"e_1_3_5_5_2","unstructured":"Decree Law no. 6 of the Italian Prime Minister February 23 2020. \u201cUrgent measures on the containment and management of the epidemiological emergency by COVID-19.\u201d https:\/\/www.gazzettaufficiale.it\/eli\/id\/2020\/02\/23\/20G00020\/sg (accessed March31 2020)."},{"key":"e_1_3_5_6_2","unstructured":"Decree Law no.14 of the Italian Prime Minister March 9 2020. \u201cFurther measures for the containment and contrast of the spread of the Covid-19 virus throughout the entire national territory.\u201d https:\/\/www.gazzettaufficiale.it\/eli\/id\/2020\/03\/09\/20G00030\/sg (accessed March31 2020)."},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12060"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12966-017-0555-2"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30547-X"},{"key":"e_1_3_5_10_2","first-page":"142","article-title":"Telemedicine in the time of the Coronavirus","volume":"39","author":"Tornese G","year":"2020","unstructured":"Tornese G, , Scaramuzza A, , Schiaffini R: Telemedicine in the time of the Coronavirus. Medico e Bambino, 2020; 39:142.","journal-title":"Medico e Bambino"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.2337\/dci19-0028"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jshs.2020.02.001"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00330"},{"key":"e_1_3_5_14_2","unstructured":"Italian Ministry of Health: Covid-19 how to follow an appropriate and healthy lifestyle when staying at home. www.salute.gov.it\/portale\/nuovocoronavirus\/dettaglioNotizieNuovoCoronavirus.jsp?lingua=italiano&menu=notizie& p\u2009=\u2009dalministero&id\u2009=\u20094421 (accessed March312020)."},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1807-59322005000100012"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-publhealth-031210-101151"}],"container-title":["Diabetes Technology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/dia.2020.0169","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/dia.2020.0169","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/dia.2020.0169","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:12:39Z","timestamp":1777399959000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/dia.2020.0169"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,29]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1089\/dia.2020.0169"],"URL":"https:\/\/doi.org\/10.1089\/dia.2020.0169","relation":{},"ISSN":["1520-9156","1557-8593"],"issn-type":[{"value":"1520-9156","type":"print"},{"value":"1557-8593","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,29]]}}}