{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:16:06Z","timestamp":1792844166813,"version":"4.5.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Technology &amp; Therapeutics"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate glycemic outcomes in the Wireless Innovation for Seniors with Diabetes Mellitus (WISDM) randomized clinical trial (RCT) participants during an observational extension phase.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Research Design and Methods:<\/jats:title>\n                    <jats:p>WISDM RCT was a 26-week RCT comparing continuous glucose monitoring (CGM) with blood glucose monitoring (BGM) in 203 adults aged \u226560 years with type 1 diabetes. Of the 198 participants who completed the RCT, 100 (98%) CGM group participants continued CGM (CGM-CGM cohort) and 94 (98%) BGM group participants initiated CGM (BGM-CGM cohort) for an additional 26 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      CGM was used a median of &gt;90% of the time at 52 weeks in both cohorts. In the CGM-CGM cohort, median time &lt;70\u2009mg\/dL decreased from 5.0% at baseline to 2.6% at 26 weeks and remained stable with a median of 2.8% at 52 weeks (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u20090.001 baseline to 52 weeks). Participants spent more time in range 70\u2013180\u2009mg\/dL (TIR) (mean 56% vs. 64%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u20090.001) and had lower hemoglobin A1c (HbA1c) (mean 7.6% [59\u2009mmol\/mol] vs. 7.4% [57\u2009mmol\/mol];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.01) from baseline to 52 weeks. In BGM-CGM, from 26 to 52 weeks median time &lt;70\u2009mg\/dL decreased from 3.9% to 1.9% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u20090.001), TIR increased from 56% to 60% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.006) and HbA1c decreased from 7.5% (58\u2009mmol\/mol) to 7.3% (57\u2009mmol\/mol) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.025). In BGM-CGM, a severe hypoglycemic event was reported for nine participants while using BGM during the RCT and for two participants during the extension phase with CGM (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      CGM use reduced hypoglycemia without increasing hyperglycemia in older adults with type 1 diabetes. These data provide further evidence for fully integrating CGM into clinical practice.\n                      <jats:uri xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/Clinicaltrials.gov\">Clinicaltrials.gov<\/jats:uri>\n                      (NCT03240432)\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/dia.2021.0503","type":"journal-article","created":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T15:47:41Z","timestamp":1647445661000},"page":"424-434","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":68,"title":["Benefit of Continuous Glucose Monitoring in Reducing Hypoglycemia Is Sustained Through 12 Months of Use Among Older Adults with Type 1 Diabetes"],"prefix":"10.1177","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5684-8284","authenticated-orcid":false,"given":"Kellee M.","family":"Miller","sequence":"first","affiliation":[{"name":"Jaeb Center for Health Research, Tampa, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4440-5168","authenticated-orcid":false,"given":"Lauren G.","family":"Kanapka","sequence":"additional","affiliation":[{"name":"Jaeb Center for Health Research, Tampa, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Rickels","sequence":"additional","affiliation":[{"name":"Rodebaugh Diabetes Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Ahmann","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes, and Clinical Nutrition, Oregon Health and Science University, Portland, Oregon, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grazia","family":"Aleppo","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Ang","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuj","family":"Bhargava","sequence":"additional","affiliation":[{"name":"Iowa Diabetes and Endocrinology Research Center, Des Moines, Iowa, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce W.","family":"Bode","sequence":"additional","affiliation":[{"name":"Formally Atlanta Diabetes Associates, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Carlson","sequence":"additional","affiliation":[{"name":"Park Nicollet International Diabetes Center, Minneapolis, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomi S.","family":"Chaytor","sequence":"additional","affiliation":[{"name":"Elson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gail","family":"Gannon","sequence":"additional","affiliation":[{"name":"Kovler Diabetes Center, University of Chicago, Chicago, Illinois, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Goland","sequence":"additional","affiliation":[{"name":"Naomi Berri Diabetes Center, Columbia University, New York, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irl B.","family":"Hirsch","sequence":"additional","affiliation":[{"name":"Division of Metabolism, Endocrinology and Nutrition, University of Washington, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Kiblinger","sequence":"additional","affiliation":[{"name":"Formally Atlanta Diabetes Associates, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davida","family":"Kruger","sequence":"additional","affiliation":[{"name":"Henry Ford Health System, Detroit, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0285-6622","authenticated-orcid":false,"given":"Yogish C.","family":"Kudva","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol J.","family":"Levy","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet B.","family":"McGill","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Metabolism &amp; Lipid Research, John T. Milliken Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grenye","family":"O'Malley","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0520-0776","authenticated-orcid":false,"given":"Anne L.","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis H.","family":"Philipson","sequence":"additional","affiliation":[{"name":"Kovler Diabetes Center, University of Chicago, Chicago, Illinois, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3986-9630","authenticated-orcid":false,"given":"Athena","family":"Philis-Tsimikas","sequence":"additional","affiliation":[{"name":"Scripps Whittier Diabetes Institute, La Jolla, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodica","family":"Pop-Busui","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maamoun","family":"Salam","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Metabolism &amp; Lipid Research, John T. Milliken Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3827-7107","authenticated-orcid":false,"given":"Viral N.","family":"Shah","sequence":"additional","affiliation":[{"name":"Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Endocrinology-Diabetes, University of Massachusetts Medical School, Worcester, Massachusetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Vendrame","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes, and Metabolism at the University of Miami School of Medicine, University of Miami, Miami, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alandra","family":"Verdejo","sequence":"additional","affiliation":[{"name":"Jaeb Center for Health Research, Tampa, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5859-5666","authenticated-orcid":false,"given":"Ruth S.","family":"Weinstock","sequence":"additional","affiliation":[{"name":"Department of Medicine, SUNY Upstate Medical University, Syracuse, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Pratley","sequence":"additional","affiliation":[{"name":"AdventHealth Translation Research Institute, Orlando, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the WISDM Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.2337\/dci19-0069"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.1824"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.6928"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199309303291401"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.2337\/dci19-0028"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc17-1600"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.18.4.517"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.10.5.617"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2015.0140"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.3102\/10769986025001060"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-1531"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc21-1667"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2021.0311"},{"key":"e_1_3_5_15_2","volume-title":"Medicare National Coverage Determinations Manual","author":"U.S. Centers for Medicare & Medicaid Services","unstructured":"U.S. Centers for Medicare & Medicaid Services: Medicare National Coverage Determinations Manual. 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