{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:43:41Z","timestamp":1790837021368,"version":"4.1.0"},"reference-count":40,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T00:00:00Z","timestamp":1674777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Technology &amp; Therapeutics"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>To assess the safety and efficacy of two exercise sessions performed 60- and 120-min postmeal with a combination of meal bolus reduction and increased glucose target to the automated insulin delivery (AID) system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A randomized crossover trial in 13 adult participants (6 females) living with type 1 diabetes using AID (A1c\u2009=\u20097.9%\u2009\u00b1\u20090.6%, age\u2009=\u200953.5\u2009\u00b1\u200915.5 years, T1D duration\u2009=\u200929.0\u2009\u00b1\u200916.0 years) was conducted. Just before breakfast, at the time of meal bolus, the AID glucose target was increased from 6 to 9\u2009mmol\/L, and a meal bolus reduction of 33% was applied. Two 60-min exercise sessions (60% of VO\n                      <jats:sub>2<\/jats:sub>\n                      peak) were undertaken either 60\u2009min (60EX) or 120\u2009min (120EX) after a standardized breakfast, followed by a 90-min recovery period.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean reduction in plasma glucose (PG) levels from prebreakfast to postexercise (\u22120.8\u2009\u00b1\u20092.4\u2009mmol\/L vs. +0.3\u2009\u00b1\u20092.3\u2009mmol\/L,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.082) were similar between 60EX and 120EX. From prebreakfast to postexercise, PG times in range (3.9\u201310.0\u2009mmol\/L; 63.4%\u2009\u00b1\u200943.1% 60EX vs. 51.9%\u2009\u00b1\u200929.7% 120EX,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.219) and time above range (&gt;10.0\u2009mmol\/L; 36.3%\u2009\u00b1\u200943.3% 60EX vs. 48.1%\u2009\u00b1\u200929.7% 120EX,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.211) did not differ between interventions. The 60EX attenuated the glucose rise between premeal to pre-exercise (+1.8\u2009\u00b1\u20092.1\u2009mmol\/L 60EX vs. +3.9\u2009\u00b1\u20092.1\u2009mmol\/L 120EX,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.001). No hypoglycemic events (&lt;3.9\u2009mmol\/L) occurred during the study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Premeal announcement combining meal bolus reduction and increased glucose target was effective and safe during 60\u2009min of moderate-intensity aerobic exercise, whether exercise onset was 60 or 120\u2009min following a meal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration No.:<\/jats:title>\n                    <jats:p>NCT04031599.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/dia.2022.0338","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T10:34:49Z","timestamp":1668767689000},"page":"122-130","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["A Randomized Crossover Pilot Study Evaluating Glucose Control During Exercise Initiated 1 or 2\u2009h After a Meal in Adults with Type 1 Diabetes Treated with an Automated Insulin Delivery System"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7146-2657","authenticated-orcid":false,"given":"\u00c9tienne","family":"Myette-C\u00f4t\u00e9","sequence":"first","affiliation":[{"name":"Montreal Clinical Research Institute, Montreal, Canada."},{"name":"Department of Applied Human Sciences, Faculty of Science, University of Prince Edward Island, Charlottetown, Canada."},{"name":"Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9phine","family":"Molveau","sequence":"additional","affiliation":[{"name":"Montreal Clinical Research Institute, Montreal, Canada."},{"name":"Department of Nutrition, Faculty of Medicine, Universit\u00e9 de Montr\u00e9al, Montreal, Canada."},{"name":"Universit\u00e9 de Lille, Universit\u00e9 d'Artois, Universit\u00e9 du Littoral C\u00f4te d'Opale, ULR 7369\u2014URePSSS\u2014Unit\u00e9 de Recherche Pluridisciplinaire Sport Sant\u00e9 Soci\u00e9t\u00e9, Lille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zekai","family":"Wu","sequence":"additional","affiliation":[{"name":"Montreal Clinical Research Institute, Montreal, Canada."},{"name":"Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, 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