{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:28:29Z","timestamp":1788316109071,"version":"build-2803163510"},"reference-count":36,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Technology &amp; Therapeutics"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To describe glucose metrics in a high-risk population of women with type 2 diabetes (T2DM) in pregnancy and to explore the associations with neonatal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Research Design and Methods:<\/jats:title>\n                    <jats:p>Prospective observational study of 57 women. Continuous glucose monitoring (CGM) trajectories were determined from metrics collected in early and late gestation using the first and last two (mean 16 and 35) weeks of Freestyle Libre data. Logistic regression was used to examine associations of CGM metrics with neonatal hypoglycemia (glucose &lt;2.6\u2009mmol\/L requiring intravenous dextrose) and large for gestational age (LGA) (&gt;90th percentile for gestational age and sex). Pregnancy-specific target glucose range was 3.5\u20137.8\u2009mmol\/L (63\u2013140\u2009mg\/dL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Forty-one women used CGM for 15 weeks (mean age 33 years, 73% Aboriginal or Torres Strait Islander, 32% living remotely). There was limited change in average metrics from early to late pregnancy. For the subgroup with sensor use &gt;50% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200929), mean time in range (TIR) increased by 9%, time above range reduced by 12%, average glucose reduced by 1\u2009mmol\/L, and time below range increased by 3%. Neonatal hypoglycemia was associated with most CGM metrics, HbA1c and CGM targets, particularly those from late pregnancy. LGA was associated with hyperglycemic metrics from early pregnancy. Each 1% increase TIR was associated with a 4%\u20135% reduction in risk of neonatal complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In this high-risk group of women with T2DM, CGM metrics only improved during pregnancy in those with greater sensor use and were associated with LGA in early pregnancy and neonatal hypoglycemia throughout. Culturally appropriate health care strategies are critical for successful use of CGM technology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/dia.2023.0300","type":"journal-article","created":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T12:14:16Z","timestamp":1698668056000},"page":"836-844","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":26,"title":["Continuous Glucose Monitoring Metrics in High-Risk Pregnant Women with Type 2 Diabetes"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5578-0188","authenticated-orcid":false,"given":"Anna","family":"McLean","sequence":"first","affiliation":[{"name":"Wellbeing and Preventable Chronic Disease Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia."},{"name":"Endocrinology Department, Cairns Hospital, Cairns, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Barr","sequence":"additional","affiliation":[{"name":"Wellbeing and Preventable Chronic Disease Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgina","family":"Tabuai","sequence":"additional","affiliation":[{"name":"Endocrinology Department, Cairns Hospital, Cairns, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen R.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Norwich Medical School, University of East Anglia, Norwich, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Maple-Brown","sequence":"additional","affiliation":[{"name":"Wellbeing and Preventable Chronic Disease Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia."},{"name":"Endocrinology Department, Royal Darwin Hospital, Darwin, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,11,23]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(20)30406-X"},{"key":"e_1_3_7_3_2","unstructured":"Papadimos EF-CC Hanley AJ Magliano DJ et al. IDF Atlas Reports Diabetes among Indigenous Peoples 2022. 2022. Available from: https:\/\/diabetesatlas.org\/atlas\/indigenous-2022 [Last accessed: October20 2023]."},{"key":"e_1_3_7_4_2","article-title":"Diabetes during pregnancy and birthweight trends among aboriginal and non-aboriginal people in the northern territory of Australia over 30 years","volume":"1","author":"Hare MJL","year":"2020","unstructured":"Hare MJL, , Barzi F, , Boyle JA, et al. Diabetes during pregnancy and birthweight trends among aboriginal and non-aboriginal people in the northern territory of Australia over 30 years. 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