{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T23:56:27Z","timestamp":1793404587375,"version":"4.5.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Technology &amp; Therapeutics"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Subcutaneous continuous glucose monitoring (CGM) may facilitate glucose control in the ICU. We aimed to assess the accuracy of CGM (Dexcom G6) against arterial blood glucose (ABG) in adult critically ill patients receiving intravenous insulin infusion and vasopressor therapy. We also aimed to assess feasibility and tolerability of CGM in this setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We included ICU patients receiving mechanical ventilation, insulin, and vasopressor therapy. Numerical accuracy was assessed by the mean absolute relative difference (MARD), overall, across arterial glucose strata, over different noradrenaline equivalent infusion rates, and over time since CGM start. MARD &lt;14% was considered acceptable. Clinical accuracy was assessed using Clarke Error Grid (CEG) analysis. Feasibility outcome included number and duration of interrupted sensor readings due to signal loss. Tolerability outcome included skin reactions related to sensor insertion or sensor adhesives.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We obtained 2946 paired samples from 40 patients (18 with type 2 diabetes) receiving a median (IQR) maximum noradrenaline equivalent infusion rate of 0.18 (0.08\u20130.33) \u00b5g\/kg\/min during CGM. Overall, MARD was 12.7% (95% CI 10.7\u201315.3), and 99.8% of CGM readings were within CEG zones A and B. MARD values \u226514% were observed when ABG was outside target range (6\u201310 mmol\/L [108\u2013180 mg\/dL]) and with noradrenaline equivalent infusion rates above 0.10 \u00b5g\/kg\/min. Accuracy improved with time after CGM start, reaching MARD values &lt;14% after 36 h. We observed four episodes of interrupted sensor readings due to signal loss, ranging from 5 to 20 min. We observed no skin reaction related to sensor insertion or sensor adhesives.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In our ICU cohort of patients receiving vasopressor infusion, subcutaneous CGM demonstrated acceptable overall numerical and clinical accuracy. However, suboptimal accuracy may occur outside glucose ranges of 6\u201310 mmol\/L (108\u2013180 mg\/dL), during higher dose vasopressor infusion, and during the first 36 h after CGM start.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/dia.2024.0035","type":"journal-article","created":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T10:45:50Z","timestamp":1715942750000},"page":"763-772","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Performance of Subcutaneous Continuous Glucose Monitoring in Adult Critically Ill Patients Receiving Vasopressor Therapy"],"prefix":"10.1177","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4436-620X","authenticated-orcid":false,"given":"Ola","family":"Friman","sequence":"first","affiliation":[{"name":"Department of Physiology and Pharmacology, Section of Anaesthesia and Intensive Care, Karolinska Institutet, Stockholm, Sweden."},{"name":"Department of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navid","family":"Soltani","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pharmacology, Section of Anaesthesia and Intensive Care, Karolinska Institutet, Stockholm, Sweden."},{"name":"Department of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Lind","sequence":"additional","affiliation":[{"name":"Department of Medicine, NU-Hospital Group, Uddevalla, Sweden."},{"name":"Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden."},{"name":"Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"Zetterqvist","sequence":"additional","affiliation":[{"name":"Department of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca","family":"Balintescu","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education, Section of Anaesthesia and Intensive Care, South General Hospital, Karolinska Institutet, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Perner","sequence":"additional","affiliation":[{"name":"Department of Intensive Care, Copenhagen University Hospital, Rigshospitalet, Denmark."},{"name":"Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Oldner","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pharmacology, Section of Anaesthesia and Intensive Care, Karolinska Institutet, Stockholm, Sweden."},{"name":"Department of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olav","family":"Rooyackers","sequence":"additional","affiliation":[{"name":"Department of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden."},{"name":"Division for Anesthesiology and Intensive Care, Department of Clinical Interventions and Technology CLINTEC, Karolinska Institutet Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8739-7896","authenticated-orcid":false,"given":"Johan","family":"M\u00e5rtensson","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pharmacology, Section of Anaesthesia and Intensive Care, Karolinska Institutet, Stockholm, Sweden."},{"name":"Department of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,10,4]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/aas.13843"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1204942"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000006174"},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.2337\/dci21-0043"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-2219"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/19322968211008446"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/1932296820964264"},{"key":"e_1_3_8_9_2","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab409"},{"issue":"3","key":"e_1_3_8_10_2","first-page":"155","article-title":"Continuous glucose monitoring for patients with COVID-19 Pneumonia: Initial experience at a tertiary care 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Continuous glucose monitoring for patients with COVID-19 Pneumonia: Initial experience at a tertiary care center. Endocr Pract Off J Am Coll Endocrinol Am Assoc Clin Endocrinol, 2023; 29(3):155\u2013161.","journal-title":"Endocr Pract Off J Am Coll Endocrinol Am Assoc Clin Endocrinol"},{"key":"e_1_3_8_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc12567"},{"key":"e_1_3_8_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/193229681300700226"},{"key":"e_1_3_8_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/nicc.12622"},{"issue":"7","key":"e_1_3_8_14_2","first-page":"4757","article-title":"Subcutaneous continuous glucose monitoring in critically ill patients during insulin therapy: A meta-analysis","volume":"14","author":"Yao Y","year":"2022","unstructured":"Yao Y, , Zhao YH, , Zheng WH, , Huang HB. Subcutaneous continuous glucose monitoring in critically ill patients during insulin therapy: A meta-analysis. 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