{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T13:40:48Z","timestamp":1777556448324,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Technology &amp; Therapeutics"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:p>\n                    Neonatal hypoglycemia (NH) is potentially life-threatening and can lead to long-term neurological sequelae. We retrospectively assessed the association between maternal glycemia in women with type 1 diabetes (T1D) and NH. Continuous glucose monitoring data from 60 mothers, alongside routine capillary blood glucose measurements from their neonates, were analyzed. The analyses used two clinically recognized thresholds for NH (&lt;2.2 mmol\/L and &lt;2.6 mmol\/L). In total, there were 25 neonates (41.7%) with NH &lt;2.6 mmol\/L and 19 neonates (31.7%) with NH &lt;2.2 mmol\/L. Neonates with NH &lt;2.2 mmol\/L were born at a lower gestational age (37.0 [35.9, 37.7] vs. 37.6 [37.0, 38.4] weeks,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.019), a higher proportion was exposed to antenatal corticosteroids (31.6% vs. 7.3%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.014), and a higher proportion required admission to the neonatal intensive care unit (42.1% vs.12.2%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.009). Similar associations were observed for NH &lt;2.6 mmol\/L, although admission rates to the neonatal intensive care unit did not reach statistical significance. Mixed-effects logistic regression analysis identified percentage time above range (odds ratio [OR] 1.047, 95% confidence interval [CI] 1.007\u20131.087,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.01) and percentage time in range (OR 0.951, 95% CI 0.914\u20130.989,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.01) as significantly associated with NH &lt;2.2 mmol\/L. Our data suggest that careful optimization of glycemia early in pregnancy, rather than in the final trimester alone, may help minimize the risk of NH in infants born to mothers with T1D.\n                  <\/jats:p>","DOI":"10.1089\/dia.2024.0477","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T12:45:59Z","timestamp":1748868359000},"page":"937-942","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Maternal Glucose and Neonatal Hypoglycemia in Pregnancy with Type 1 Diabetes: A Continuous Glucose Monitoring Cohort"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8496-6790","authenticated-orcid":false,"given":"Lukana","family":"Preechasuk","sequence":"first","affiliation":[{"name":"Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom."},{"name":"Siriraj Diabetes Center of Excellence, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9047-3589","authenticated-orcid":false,"given":"Parizad","family":"Avari","sequence":"additional","affiliation":[{"name":"Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom."},{"name":"Department of Diabetes and Endocrinology, Imperial College Healthcare NHS Trust, London, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Godsland","sequence":"additional","affiliation":[{"name":"Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Endocrinology, Chelsea and Westminster Hospital, London, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chukwuma","family":"Uduku","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Endocrinology, Imperial College Healthcare NHS Trust, London, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ed","family":"Mullins","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynaecology, Imperial College Healthcare NHS Trust, London, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3525-3633","authenticated-orcid":false,"given":"Nick","family":"Oliver","sequence":"additional","affiliation":[{"name":"Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom."},{"name":"Department of Diabetes and Endocrinology, Imperial College Healthcare NHS Trust, London, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rochan","family":"Agha-Jaffar","sequence":"additional","affiliation":[{"name":"Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom."},{"name":"Department of Diabetes and Endocrinology, Imperial College Healthcare NHS Trust, London, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2016.08.007"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-1755"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1568985"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/dme.13988"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2822"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000492859"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.35989"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2015.1631"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.06.044"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2017-314050"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-3851"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2016-311473"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(17)32400-5"},{"key":"e_1_3_4_15_2","unstructured":"National Institute for Health and Care Excellence. Diabetes in pregnancy: Management from preconception to the postnatal period (NG13)."},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/dme.13546"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0707943"},{"key":"e_1_3_4_18_2","unstructured":"Gardosi J W A Hugh O Francis A. Customised Centile Calculator. GROW version 2.1.6.1. 2023. 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