{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T11:18:57Z","timestamp":1771327137171,"version":"3.50.1"},"reference-count":17,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1988,4,1]],"date-time":"1988-04-01T00:00:00Z","timestamp":575856000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DNA"],"published-print":{"date-parts":[[1988,4]]},"DOI":"10.1089\/dna.1988.7.211","type":"journal-article","created":{"date-parts":[[2009,3,25]],"date-time":"2009-03-25T16:21:17Z","timestamp":1237998077000},"page":"211-217","source":"Crossref","is-referenced-by-count":3,"title":["Site-Specific Oligonucleotide-Directed Mutagenesis Using T4 DNA Polymerase"],"prefix":"10.1177","volume":"7","author":[{"given":"GWONG-JEN J.","family":"CHANG","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BARBARA J.B.","family":"JOHNSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DENNIS W.","family":"TRENT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"p_34","doi-asserted-by":"publisher","DOI":"10.1126\/science.2994214"},{"key":"p_35","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/13.12.4431"},{"key":"p_36","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-68-8-2129"},{"key":"p_37","doi-asserted-by":"publisher","DOI":"10.1016\/0147-619X(85)90053-8"},{"key":"p_38","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/14.12.5115"},{"key":"p_39","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.1016\/S0021-9258(19)45224-1","volume":"247","author":"HUANG W.M.","year":"1972","journal-title":"J. Biol. Chem."},{"key":"p_40","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/10.20.6475"},{"key":"p_41","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/12.24.9441"},{"key":"p_42","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.2.488"},{"key":"p_43","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.19.7177"},{"key":"p_44","doi-asserted-by":"publisher","DOI":"10.1016\/0076-6879(83)01005-8"},{"key":"p_45","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/11.15.5103"},{"key":"p_46","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.12.5463"},{"key":"p_47","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(80)90196-5"},{"key":"p_48","doi-asserted-by":"publisher","DOI":"10.1089\/dna.1.1984.3.469"},{"key":"p_49","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/13.24.8765"},{"key":"p_50","first-page":"469","volume":"101","author":"ZOLLER M.J.","year":"1983","journal-title":"Methods Enzymol."}],"container-title":["DNA"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/dna.1988.7.211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T10:21:13Z","timestamp":1771323673000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/dna.1988.7.211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,4]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1988,4]]}},"alternative-id":["10.1089\/dna.1988.7.211"],"URL":"https:\/\/doi.org\/10.1089\/dna.1988.7.211","relation":{},"ISSN":["0198-0238"],"issn-type":[{"value":"0198-0238","type":"print"}],"subject":[],"published":{"date-parts":[[1988,4]]}}}