{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T18:36:16Z","timestamp":1792521376941,"version":"4.5.0"},"reference-count":46,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["DNA and Cell Biology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Acinetobacter baumannii<\/jats:italic>\n                    is a highly antibiotic-resistant bacterial pathogen known to cause severe life-threatening infections, including pneumonia, meningitis, and sepsis. Recent emergence of this bacterium as a serious nosocomial pathogen has led to categorization of\n                    <jats:italic toggle=\"yes\">A. baumannii<\/jats:italic>\n                    as a \u201chigh-priority\u201d pathogen by the World Health Organization (WHO), for which research efforts are urgently required to develop therapeutic interventions. Some of the properties that make\n                    <jats:italic toggle=\"yes\">A. baumannii<\/jats:italic>\n                    a serious pathogen include its capacity to tolerate high levels of stress and enhanced expression of efflux pumps that enable high degrees of antibiotic resistance. Virulence mechanisms employed by\n                    <jats:italic toggle=\"yes\">A. baumannii<\/jats:italic>\n                    to establish successful infection and host responses elicited against\n                    <jats:italic toggle=\"yes\">A. baumannii<\/jats:italic>\n                    to counter the infection are discussed in detail in this article.\n                  <\/jats:p>","DOI":"10.1089\/dna.2021.0588","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T16:20:06Z","timestamp":1640276406000},"page":"43-48","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":47,"title":["<i>Acinetobacter baumannii<\/i>\n                    : Virulence Strategies and Host Defense Mechanisms"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0566-4821","authenticated-orcid":false,"given":"Varnesh","family":"Tiku","sequence":"first","affiliation":[{"name":"Vir Biotechnology, San Francisco, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,1,12]]},"reference":[{"key":"e_1_3_3_2_1","first-page":"49","article-title":"Reservoirs of non-baumannii Acinetobacter species","author":"Al Atrouni A.","year":"2016","unstructured":"Al Atrouni A., , Joly-Guillou M.-L., , Hamze M., , and Kempf M. (2016). Reservoirs of non-baumannii Acinetobacter species. Front Microbiol 7, 49.","journal-title":"Front Microbiol 7,"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022674"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1523116113"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01459-13"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00069-11"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2005.00538.x"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-8-216"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02992-14"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/15.4.748"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00762-07"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01897-14"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2012.12.002"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004691"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2009.10.024"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2015.12.012"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/lam.12627"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2017.148"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005391"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1317052110"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep20724"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2014.1966"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2009.01820.x"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M117.808394"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200505-730OC"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2009.01669.x"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.12300"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00312-12"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00016-10"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0010033"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12275-012-1555-1"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00410-15"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01029-08"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040019"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.02034-14"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00366-10"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2015.09.015"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit386"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02101-13"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033073"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1009802"},{"key":"e_1_3_3_42_1","unstructured":"Tacconelli E. and Margrini N. (2013). Global priority list of antibiotic-resistant bacteria to guide research discovery and development of new antibiotics. WHO. https:\/\/www.who.int\/medicines\/publications\/WHO-PPL-Short_Summary_25Feb-ET_NM_WHO.pdf (accessed December16 2021)."},{"key":"e_1_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01944-13"},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-79966-9"},{"key":"e_1_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2020.01.006"},{"key":"e_1_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1502966112"},{"key":"e_1_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00058-16"}],"container-title":["DNA and Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/dna.2021.0588","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/dna.2021.0588","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/dna.2021.0588","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:59:24Z","timestamp":1777399164000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/dna.2021.0588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1089\/dna.2021.0588"],"URL":"https:\/\/doi.org\/10.1089\/dna.2021.0588","relation":{},"ISSN":["1044-5498","1557-7430"],"issn-type":[{"value":"1044-5498","type":"print"},{"value":"1557-7430","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]}}}