{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:22:02Z","timestamp":1791400922977,"version":"4.3.3"},"reference-count":50,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DNA and Cell Biology"],"published-print":{"date-parts":[[2024,6,1]]},"DOI":"10.1089\/dna.2023.0411","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T15:35:46Z","timestamp":1713800146000},"page":"288-297","source":"Crossref","is-referenced-by-count":5,"title":["Bone Remodeling and Bone Structural Genes in Legg\u2013Calv\u00e9\u2013Perthes Disease: The\n                    <i>OPG<\/i>\n                    rs2073618 and\n                    <i>IL-6<\/i>\n                    rs1800795 Are Associated with High Risk in Mexican Patients"],"prefix":"10.1177","volume":"43","author":[{"given":"Blanca Luc\u00eda","family":"Cruz-Ort\u00edz","sequence":"first","affiliation":[{"name":"Escuela Nacional de Ciencias Biol\u00f3gicas, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7511-4155","authenticated-orcid":false,"given":"Edgar","family":"Hern\u00e1ndez-Zamora","sequence":"additional","affiliation":[{"name":"Medicina Gen\u00f3mica, Instituto Nacional de Rehabilitaci\u00f3n, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elba","family":"Reyes-Maldonado","sequence":"additional","affiliation":[{"name":"Escuela Nacional de Ciencias Biol\u00f3gicas, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando Odiseo","family":"Rodr\u00edguez-Olivas","sequence":"additional","affiliation":[{"name":"Escuela Nacional de Ciencias Biol\u00f3gicas, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julieta","family":"Rubio-Lightbourn","sequence":"additional","affiliation":[{"name":"Medicina Gen\u00f3mica y Toxicolog\u00eda Ambiental, Instituto de Investigaciones Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celeste O.","family":"Mart\u00ednez-Ram\u00edrez","sequence":"additional","affiliation":[{"name":"Facultad de Nutrici\u00f3n, Universidad Aut\u00f3noma del Estado de Morelos, Cuernavaca, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clementina","family":"Castro-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Medicina Gen\u00f3mica y Toxicolog\u00eda Ambiental, Instituto de Investigaciones Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Lezama-Palacios","sequence":"additional","affiliation":[{"name":"Escuela Nacional de Ciencias Biol\u00f3gicas, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6238-4538","authenticated-orcid":false,"given":"Leonora","family":"Casas-Avila","sequence":"additional","affiliation":[{"name":"Medicina Gen\u00f3mica, Instituto Nacional de Rehabilitaci\u00f3n, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/1285216"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1080\/15513815.2019.1693671"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2004.08.006"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.32598\/jpr.9.4.964.1"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jor.2018.08.042"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.25259\/JMSR_123_2021"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1038\/nature01658"},{"key":"B8","unstructured":"Browner WS, Black D, Newman TB, et al. Estimaci\u00f3n del Tama\u00f1o de Muestra y de la Potencia. In: Dise\u00f1o de la Investigaci\u00f3n Clinica. Un Enfoque Epidemiol\u00f3gico (Hulley SB, Cummings SR. eds.). Doyma editors. Travesera de Gracia, 17\u201321. 0821, Barcelona, Spain, 1993; pp. 152\u2013165, 232."},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-022-02264-2"},{"issue":"9","key":"B10","first-page":"139","volume":"136","author":"Choi G","year":"2006","journal-title":"Swiss Med Wkly"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1080\/17453670510045462"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.4274\/tjh.galenos.2018.2018.0221"},{"issue":"7","key":"B13","first-page":"614","volume":"8","author":"Garc\u00eda-Alfaro MD","year":"2021","journal-title":"Children (Basel, Switzerland)"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1046793"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0148-0"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.3109\/17453670903025378"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1177\/10760296221151166"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1002\/jbm4.10429"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2435"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1177\/0004563218759371"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.060905"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-201011000-00005"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2011.04.007"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0b013e31802d976f"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1186\/1878-5085-4-15"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22415"},{"issue":"6","key":"B27","first-page":"e100505","volume":"9","author":"Li N","year":"2014","journal-title":"Gly630Ser mutation of COL2A1 in a Chinese family with presentations of Legg\u2013Calv\u00e9\u2013Perthes disease or avascular necrosis of the femoral head. PLoS One"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-015-0730-z"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.5402\/2011\/504393"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.15246"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2016.06.010"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.3390\/jcm6070063"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1160\/TH05-01-0047"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2017.1295850"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-13-40"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.3390\/genes13020290"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.5312\/wjo.v10.i3.145"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-0243"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsams.2007.12.006"},{"issue":"3","key":"B40","first-page":"149","volume":"3","author":"Pouya F","year":"2015","journal-title":"Arch Bone Jt Surg"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-022-02275-z"},{"issue":"3","key":"B42","first-page":"471","volume":"13","author":"Spasovski V","year":"2023","journal-title":"Diagnostics (Basel, Switzerland)"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.2298\/SARH1408450S"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-015-2510-z"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1002\/art.23491"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.18535\/jmscr\/v7i1.128"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.I.00157"},{"issue":"3","key":"B48","first-page":"213","volume":"21","author":"Wang T","year":"2020","journal-title":"Current Drug Targets"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22473"},{"issue":"9","key":"B50","first-page":"14764","volume":"8","author":"Xie P","year":"2015","journal-title":"Int J Clin Exp Med"}],"container-title":["DNA and Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/dna.2023.0411","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/dna.2023.0411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:00:12Z","timestamp":1777399212000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/dna.2023.0411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,1]]},"references-count":50,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6,1]]}},"alternative-id":["10.1089\/dna.2023.0411"],"URL":"https:\/\/doi.org\/10.1089\/dna.2023.0411","relation":{},"ISSN":["1044-5498","1557-7430"],"issn-type":[{"value":"1044-5498","type":"print"},{"value":"1557-7430","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,1]]}}}