{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T22:48:48Z","timestamp":1774651728177,"version":"3.50.1"},"reference-count":0,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2000,10,1]],"date-time":"2000-10-01T00:00:00Z","timestamp":970358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Endourology"],"published-print":{"date-parts":[[2000,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>The study was designed to explore the relation between prostatic temperature and the clinical outcome of transurethral microwave thermotherapy (TUMT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>Forty-nine patients with symptomatic benign prostatic hyperplasia (BPH) were treated. Baseline evaluation included Madsen score, flowmetry, and pressure-flow study. Two fiberoptic thermosensors were placed in the prostate targeted to the region 10 and 20 mm below the bladder neck and 5 to 15 mm lateral to the prostatic urethra. The TUMT was carried out using either the low-energy (2.0) or high-energy (2.5) Prostasoft program. Follow-up was at 6,12, and 26 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A moderate correlation between intraprostatic temperatures and energy output (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      = 0.409;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2264 0.046) and prostate volume (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      = 0.303;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2264 0.0424) was observed. Outlet obstruction was associated with higher temperatures (obstructed 49.6 \u00b1 5.8\n                      <jats:italic toggle=\"yes\">v<\/jats:italic>\n                      unobstructed 46.1 \u00b1 4.2\u00b0C;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2264 0.033). A significant relation between temperature and clinical outcome was found. Patients with intraprostatic temperatures &lt;46\u00b0, 46\u221250\u00b0, and \u226450\u00b0C had significant differences in Madsen score change (\u221250%, \u221268% and \u221286%) and in maximum flow rate (+26%, +32%, and +48%). Patients with temperatures &gt;50\u00b0C had a significant improvement in obstruction status (86% to 18%). A slight worsening in voiding dynamics was observed in patients with temperatures &lt;50\u00b0C.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>A significant relation exists between intraprostatic temperatures achieved during TUMT and the clinical outcome. Temperatures in excess of 50\u00b0C seem to be associated with a greater improvement in lower urinary tract symptoms and bladder outlet obstruction. These data provide a sound rationale for monitoring intraprostatic temperatures and developing invasive thermometry feedback mechanisms for thermal treatments of BPH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/end.2000.14.617","type":"journal-article","created":{"date-parts":[[2009,3,17]],"date-time":"2009-03-17T03:02:47Z","timestamp":1237258967000},"page":"617-625","source":"Crossref","is-referenced-by-count":12,"title":["Relation Between Intraprostatic Temperature and Clinical Outcome in Microwave Thermotherapy"],"prefix":"10.1177","volume":"14","author":[{"given":"Simon","family":"Carter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Tubaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2000,10,1]]},"container-title":["Journal of Endourology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/end.2000.14.617","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/end.2000.14.617","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T21:50:07Z","timestamp":1774648207000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/end.2000.14.617"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,10]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2000,10]]}},"alternative-id":["10.1089\/end.2000.14.617"],"URL":"https:\/\/doi.org\/10.1089\/end.2000.14.617","relation":{},"ISSN":["0892-7790","1557-900X"],"issn-type":[{"value":"0892-7790","type":"print"},{"value":"1557-900X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,10]]}}}