{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:33:53Z","timestamp":1777588433606,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endourology"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>This study was to evaluate the effect of intraoperative continuous infusion of dexmedetomidine on intraocular pressure (IOP) in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALRP) in the steep Trendelenburg (ST).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Sixty-eight patients were randomly divided into two groups. The dexmedetomidine group (Group D,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      =34) received a continuous infusion of dexmedetomidine at a rate of 0.4\u2009\u03bcg kg\n                      <jats:sup>\u22121<\/jats:sup>\n                      hour\n                      <jats:sup>\u22121<\/jats:sup>\n                      from the induction of anesthesia until the end of the ST position, while the control group (Group C,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      =34) received an equal volume of physiologic saline at the same rate under conventional general anesthesia with sevoflurane and remifentanil. IOP was measured at 11 predefined time points for all patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Significant differences in IOP were detected between the two groups by a linear mixed model analysis (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt;0.001). The highest mean IOP was 19.9\u00b15.0\u2009mm Hg in Group D and 25.7\u00b15.0\u2009mm Hg in Group C; both were measured 60 minutes after the patients had been placed in the ST position. No significant between-group differences in ocular perfusion pressure, mean blood pressure, or heart rate were observed between the two groups. No ocular or other complications were noted.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Intraoperative continuous infusion of dexmedetomidine may help alleviate IOP increase in patients undergoing RALRP in the ST position.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/end.2014.0381","type":"journal-article","created":{"date-parts":[[2014,8,19]],"date-time":"2014-08-19T10:01:38Z","timestamp":1408442498000},"page":"310-316","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":29,"title":["The Effect of Dexmedetomidine on Intraocular Pressure Increase in Patients During Robot-Assisted Laparoscopic Radical Prostatectomy in the Steep Trendelenburg Position"],"prefix":"10.1177","volume":"29","author":[{"given":"Na Young","family":"Kim","sequence":"first","affiliation":[{"name":"Yonsei University College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Chul","family":"Yoo","sequence":"additional","affiliation":[{"name":"Yonsei University College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HeeJoon","family":"Park","sequence":"additional","affiliation":[{"name":"Yonsei University College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Deuk","family":"Choi","sequence":"additional","affiliation":[{"name":"Yonsei University College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chan Yun","family":"Kim","sequence":"additional","affiliation":[{"name":"Yonsei University College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Joon","family":"Bai","sequence":"additional","affiliation":[{"name":"Yonsei University College of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,3,1]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"531","article-title":"Perioperative visual loss in ocular and nonocular surgery","volume":"4","author":"Berg KT","year":"2010","unstructured":"Berg KT, , Harrison AR, , Lee MS. 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