{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:55:52Z","timestamp":1777589752319,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endourology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction and Objective:<\/jats:title>\n                    <jats:p>\n                      Robotic radical nephroureterectomy (RRNU) may offer advantages over laparoscopic radical nephroureterectomy (LRNU). The purpose of this study is to evaluate the overall survival (OS) of patients with upper tract urothelial carcinoma (UTUC) who underwent RRNU\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      LRNU and identify factors that account for differences.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The National Cancer Database was queried from 2010 to 2016 for patients with American Joint Committee on Cancer 6th\/7th edition Stage I\/II\/III UTUC. Kaplan\u2013Meier analysis compared LRNU and RRNU OS. Univariate analysis detected differences between the groups. Cox regression determined factors associated with mortality rate. Logistic regression identified predictors of a lymph node dissection (LND) and 90-day mortality rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 2631 patients met the criteria, 1129 of whom underwent RRNU and 1502 LRNU, with a follow-up of 33 and 35 months, respectively (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.063). RRNU had a median OS of 71.1\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      62.6 months (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.033). LRNU patients were older (72.7\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      71.4,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and had no differences in comorbidities, pathologic T stage, or grade. The LRNU cohort was less likely to undergo LND (19%\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      35%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and had a lower median lymph node yield (3\n                      <jats:italic toggle=\"yes\">vs<\/jats:italic>\n                      4,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). LRNU patients more likely underwent conversion to an open procedure, had longer hospital stays, and higher 30- and 90-day mortality rates. LRNU was independently associated with mortality rate (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.030). Age, grade, positive margins, pT\/pN stage were associated with mortality rate. Younger age, RRNU, surgery at an academic center, and neoadjuvant chemotherapy predicted an LND.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>RRNU demonstrated increased rates of LND and may offer a short-term morbidity benefit to LRNU. Survival differences may be due to improved characterization of disease through LND.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/end.2020.0496","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T03:10:00Z","timestamp":1603249800000},"page":"312-318","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":32,"title":["Robotic Nephroureterectomy\n                    <i>vs<\/i>\n                    Laparoscopic Nephroureterectomy: Increased Utilization, Rates of Lymphadenectomy, Decreased Morbidity Robotically"],"prefix":"10.1177","volume":"35","author":[{"given":"Alexander P.","family":"Kenigsberg","sequence":"first","affiliation":[{"name":"Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wesley","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaosong","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rashed","family":"Ghandour","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonid","family":"Rapoport","sequence":"additional","affiliation":[{"name":"Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditya","family":"Bagrodia","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yair","family":"Lotan","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Solomon L.","family":"Woldu","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vitaly","family":"Margulis","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA."},{"name":"Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,3,1]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21332"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2017.07.036"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2019.12.29"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aju.2017.05.002"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.03.072"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2010.09826.x"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.06.013"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2017.10.003"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2012.11474.x"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.04.052"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2010.02610.x"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.02.021"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30516"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-016-1764-z"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.02.030"},{"key":"e_1_3_4_17_2","first-page":"31","article-title":"Adjuvant chemotherapy for upper-tract urothelial carcinoma treated with nephroureterectomy: Assessment of adequate renal function and influence on outcome","volume":"32","author":"Yafi FA","year":"2014","unstructured":"Yafi FA, , Tanguay S, , Rendon R, et al. Adjuvant chemotherapy for upper-tract urothelial carcinoma treated with nephroureterectomy: Assessment of adequate renal function and influence on outcome. 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