{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:52:36Z","timestamp":1792000356507,"version":"4.4.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endourology"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To test the effectiveness (Participant A) and tolerability (Participant B) of urinary stone comminution in the first-in-human trial of a new technology, burst-wave lithotripsy (BWL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>An investigational BWL and ultrasonic propulsion system was used to target a 7-mm kidney stone in the operating room before ureteroscopy (Participant A). The same system was used to target a 7.5\u2009mm ureterovesical junction stone in clinic without anesthesia (Participant B).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>For Participant A, a ureteroscope inserted after 9 minutes of BWL observed fragmentation of the stone to &lt;2\u2009mm fragments. Participant B tolerated the procedure without pain from BWL, required no anesthesia, and passed the stone on day 15.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The first-in-human tests of BWL pulses were successful in that a renal stone was comminuted in &lt;10 minutes, and BWL was also tolerated by an awake subject for a distal ureteral stone.<\/jats:p>\n                    <jats:p>Clinical Trial NCT03873259 and NCT02028559.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/end.2020.0725","type":"journal-article","created":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T05:15:42Z","timestamp":1600319742000},"page":"506-511","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["First In-Human Burst Wave Lithotripsy for Kidney Stone Comminution: Initial Two Case Studies"],"prefix":"10.1177","volume":"35","author":[{"given":"Jonathan D.","family":"Harper","sequence":"first","affiliation":[{"name":"Department of Urology and University of Washington School of Medicine, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Metzler","sequence":"additional","affiliation":[{"name":"Department of Urology and University of Washington School of Medicine, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Kennedy","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Washington School of Medicine, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony T.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology and University of Washington School of Medicine, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam D.","family":"Maxwell","sequence":"additional","affiliation":[{"name":"Department of Urology and University of Washington School of Medicine, Seattle, Washington, USA."},{"name":"Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan W.","family":"Cunitz","sequence":"additional","affiliation":[{"name":"Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbrina","family":"Dunmire","sequence":"additional","affiliation":[{"name":"Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeff","family":"Thiel","sequence":"additional","affiliation":[{"name":"Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C.","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Cell Biology &amp; Physiology, Indiana University School of Medicine, Indianapolis, Indiana, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Bailey","sequence":"additional","affiliation":[{"name":"Department of Urology and University of Washington School of Medicine, Seattle, Washington, USA."},{"name":"Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathew D.","family":"Sorensen","sequence":"additional","affiliation":[{"name":"Department of Urology and University of Washington School of Medicine, Seattle, Washington, USA."},{"name":"Division of Urology, VA Puget Sound Health Care System, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,4,1]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"crossref","unstructured":"Ramesh S Chen TT Maxwell AD et al. 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