{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T23:01:53Z","timestamp":1781218913688,"version":"3.54.1"},"reference-count":27,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endourology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To evaluate the risk of residual tumor and tumor upstaging during a second resection after primary complete transurethral resection of bladder tumor (TURBT) using photodynamic diagnosis (PDD) for high-risk nonmuscle invasive bladder cancer (NMIBC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>\n                      From January 2014 to March 2020, a single-institutional study was conducted including consecutive patients with high-risk NMIBC (T1 and\/or\n                      <jats:italic toggle=\"yes\">cis<\/jats:italic>\n                      and\/or high grade) who underwent a restaging transurethral resection (reTUR) within 12 weeks after a primary complete resection. Each TURBT was performed using blue light after intravesical instillation of hexaminolevulinate. The primary endpoint was detection of residual tumor at reTUR, proved with positive pathology report.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 109 consecutive patients with high-risk NMIBC underwent reTUR after a primary complete blue light resection. Pathologic evaluation of the surgical specimens of the primary TURBT revealed stage T1 and high-grade tumors in 69 (68.3%) and 108 (99%) patients, respectively, and concomitant carcinoma\n                      <jats:italic toggle=\"yes\">in situ<\/jats:italic>\n                      was found in 45 patients (41.3%). The median time to reTUR was 8 (6\u201310) weeks. Residual tumor was detected histopathologically in 64 of 109 patients (58.7%) at the second TURBT with PDD. In five of these patients (4.5%), initial T1 tumors were upstaged to T2 tumors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>We examined a contemporary series of patients undergoing reTUR with PDD as management of high-risk NMIBC proven at the first blue light resection. We reported a 54.2% risk of disease persistence and a 4.5% risk of understaging in T1 tumors. These findings support that reTUR is still necessary after initial complete TURBT with PDD. Further studies are needed to assess the long-term oncologic outcomes of reTUR with PDD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/end.2020.1107","type":"journal-article","created":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T04:42:36Z","timestamp":1614228156000},"page":"1042-1046","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Primary Complete Transurethral Resection of Bladder Tumor Using Photodynamic Diagnosis for High-Risk Nonmuscle Invasive Bladder Cancer: Is a Restaging Photodynamic Transurethral Resection Really Necessary?"],"prefix":"10.1177","volume":"35","author":[{"given":"Abel","family":"Tadrist","sequence":"first","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastien","family":"Gondran-Tellier","sequence":"additional","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"McManus","sequence":"additional","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid","family":"Al Balushi","sequence":"additional","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akram","family":"Akiki","sequence":"additional","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Gaillet","sequence":"additional","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronique","family":"Delaporte","sequence":"additional","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Karsenty","sequence":"additional","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Lechevallier","sequence":"additional","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Boissier","sequence":"additional","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Baboudjian","sequence":"additional","affiliation":[{"name":"Department of Urology and Kidney Transplantation, Conception Academic Hospital, Aix-Marseille University, APHM, Marseille, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,7,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20138"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-015-1739-2"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.12.031"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0302-2838(02)00068-4"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2018.02.014"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.06.005"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.11.041"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.10.061"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2020.0011"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.08.016"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2004.05715.x"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000181814.73466.14"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)37779-0"},{"key":"e_1_3_3_15_2","first-page":"48","article-title":"ALA fluorescent diagnosis of bladder cancer","volume":"5","author":"Kh Al\u2019-Shukri S","year":"2000","unstructured":"Kh Al\u2019-Shukri S, , Danil'chenko DI, , K\u00ebnig F, et al. ALA fluorescent diagnosis of bladder cancer. Urologiia, 2000; 5: 48.","journal-title":"Urologiia"},{"key":"e_1_3_3_16_2","first-page":"208","article-title":"The value of secondary transurethral resection for superficial bladder tumors","volume":"25","author":"K\u00f6hrmann KU","year":"1994","unstructured":"K\u00f6hrmann KU, , Woeste M, , Kappes J, et al. The value of secondary transurethral resection for superficial bladder tumors. Akt Urol, 1994; 25:208.","journal-title":"Akt Urol"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.06.148"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)66442-7"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0266462310001364"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2003.12.016"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(75)90367-2"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13599"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2017.05.040"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.05.047"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64993-2"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)01920-9"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199907000-00018"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13102"}],"container-title":["Journal of Endourology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/end.2020.1107","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/end.2020.1107","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/end.2020.1107","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T20:18:42Z","timestamp":1777407522000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/end.2020.1107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1089\/end.2020.1107"],"URL":"https:\/\/doi.org\/10.1089\/end.2020.1107","relation":{},"ISSN":["0892-7790","1557-900X"],"issn-type":[{"value":"0892-7790","type":"print"},{"value":"1557-900X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}