{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:35:23Z","timestamp":1777588523518,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Endourology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>\n                      To evaluate the clearance of metal particles produced and released in the pelvicaliceal system (PCS) during percutaneous nephrolithotomy (PCNL) with the use of the Swiss Lithoclast\n                      <jats:sup>\u00ae<\/jats:sup>\n                      Trilogy dual-energy (EMS Urology, Nyon, Switzerland) lithotripter.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      An experimental\n                      <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                      study and a clinical investigation of case series were conducted. An\n                      <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                      porcine model with two pigs for lithotripsy (after inserting artificial stones into the collecting system) and two pigs for submucosal injection of metal particles (provided by the manufacturer of Trilogy) was conducted. Porcine kidney histology analysis for metal leftovers was conducted immediately or 2 weeks after the surgery. A prospective observational study design included 10 consecutive patients treated with conventional 30F PCNL or with 22F mini-PCNL technique. Only the patients with the confirmed metal particles in the PCS during the initial PCNL and the need for additional retrograde intrarenal surgery over a period of 2\u20134 weeks were selected. The presence of metal particles was evaluated during the second endoscopic surgery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The generated metal particles during PCNL and the submucosally injected particles were not found macroscopically 2 weeks postoperatively in porcine models. No pathologic changes such as foreign body granuloma or inflammation were found. Similarly, no metal particles were observed during the second look endoscopy (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200910).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Metal particles observed endoscopically using the Trilogy lithotripter are cleared with no pathologic evidence of tissue damage from the metal particles 2 weeks after the procedure. Thus, the intraoperative release of any particle by the Trilogy lithotripter should not raise any safety concerns.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/end.2022.0322","type":"journal-article","created":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T11:22:08Z","timestamp":1660648928000},"page":"15-20","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clearance of Metal Particles After Percutaneous Nephrolithotomy with Trilogy Lithotripter"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5845-7420","authenticated-orcid":false,"given":"Anastasios","family":"Natsos","sequence":"first","affiliation":[{"name":"Department of Urology, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2499-7015","authenticated-orcid":false,"given":"Arman","family":"Tsaturyan","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0427-4506","authenticated-orcid":false,"given":"Angelis","family":"Peteinaris","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constantinos","family":"Adamou","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Pagonis","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasiliki","family":"Bravou","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitra","family":"Koumoundourou","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theofanis","family":"Vrettos","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and ICU, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Kagadis","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Giannitsas","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagiotis","family":"Kallidonis","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital of Patras, Patras, Greece."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelos","family":"Liatsikos","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital of Patras, Patras, Greece."},{"name":"Department of Urology, Medical University of Vienna, Vienna, Austria."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,1,1]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2015.07.041"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2018.12.006"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2020.1143"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-019-02843-2"},{"issue":"12","key":"e_1_3_7_6_2","first-page":"655","article-title":"Tissue damage during percutaneous ultrasonic lithotripsy]","volume":"78","author":"Stackl W","year":"1985","unstructured":"Stackl W, , Marberger M. 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