{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:34:02Z","timestamp":1777642442499,"version":"3.51.4"},"reference-count":54,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foodborne Pathogens and Disease"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    is estimated to be one of the leading causes of enteric illness worldwide. Human salmonellosis is most frequently related to contaminated food products, particularly those of animal origin, such as pork. Pigs are often asymptomatic carriers of\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    , highlighting the importance of identifying high-prevalence farms and effective detection methods. The objectives of this study were to investigate\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    antibody responses and their association with on-farm shedding and\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    isolation at slaughter. Fourteen groups of pigs from eight farrowing sources were followed from birth to slaughter (totaling 796 pigs). Information about farm management was collected through a questionnaire. Blood and fecal samples were collected four times at different stages of production, and palatine tonsils\/submandibular lymph nodes were obtained at slaughter. Sera were tested for\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    antibodies by enzyme-linked immunosorbent assay, and fecal\/tissue samples were cultured for\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    . Data were analyzed using a mixed-effect multivariable modeling method with farm, litter, and pig as random effects.\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    seropositivity rates were 20.3%, 5.8%, 15.9%, and 37.3% at weaning, at the end of nursery, at end of grower, and at end of finisher, respectively.\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    seropositivity and shedding increased with age (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.05), and pigs shedding\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    were more likely to test seropositive (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u20090.02). Antibody response and shedding on-farm had no significant association with isolation of\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    from tissues harvested at slaughter. The variation in\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    seropositivity due to farm was 28.9% of total variation. These findings indicate that on-farm intervention may be a more effective approach to control\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    and to reduce the presence of\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    at slaughter. Additionally, the observation that some pigs in this study were\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    -negative throughout production and at slaughter is promising with regard to food safety, and studies are needed to explore the genotypes of those pigs.\n                  <\/jats:p>","DOI":"10.1089\/fpd.2018.2454","type":"journal-article","created":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T15:31:35Z","timestamp":1543332695000},"page":"187-194","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Antibody Responses to\n                    <i>Salmonella<\/i>\n                    in Pigs from Weaning Up to Marketing and Presence of\n                    <i>Salmonella<\/i>\n                    at Slaughter"],"prefix":"10.1177","volume":"16","author":[{"given":"Corinne H.","family":"Schut","sequence":"first","affiliation":[{"name":"University of Guelph","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdolvahab","family":"Farzan","sequence":"additional","affiliation":[{"name":"University of Guelph","place":["Canada"]},{"name":"University of Guelph","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret H.","family":"Ainslie-Garcia","sequence":"additional","affiliation":[{"name":"University of Guelph","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert M.","family":"Friendship","sequence":"additional","affiliation":[{"name":"University of Guelph","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon N.","family":"Lillie","sequence":"additional","affiliation":[{"name":"University of Guelph","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,3,6]]},"reference":[{"key":"e_1_3_3_2_1","first-page":"249","article-title":"Salmonella fecal shedding in pigs from birth to market and its association with the presence of Salmonella in palatine tonsils and sub-mandibular lymph node","volume":"82","author":"Ainslie-Garcia MH","year":"2018","unstructured":"Ainslie-Garcia MH, , Farzan A, , Newman J, , Friendship RM, , Lillie BN. Salmonella fecal shedding in pigs from birth to market and its association with the presence of Salmonella in palatine tonsils and sub-mandibular lymph node. 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