{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:31:37Z","timestamp":1777642297753,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foodborne Pathogens and Disease"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    producing \u03b2-lactamases has spread rapidly worldwide and poses a serious threat to human and animal health. In this study, we characterized 220 ceftriaxone (CRO)-resistant isolates identified among 3153\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    from humans, animals, food, and water collected in Shanghai, China. They were assessed for antimicrobial susceptibility, phenotypic identification of extended-spectrum \u03b2-lactamases (ESBLs), and \u03b2-lactamase genes and integrons. CRO resistance in\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    increased from 5.0% in 2011 to 8.4% in 2013.\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    Enteritidis (45.5%),\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    Typhimurium (20.9%) from humans, and\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    Indiana (14.5%) from poultry represented the majority of the CRO-resistant isolates. Many isolates were also resistant to other antimicrobials, including nalidixic acid (84.5%), sulfisoxazole (70.5%), and tetracycline (61.8%). Resistance to ciprofloxacin was also found in 33.6% of the isolates. Most isolates (98.2%) were confirmed as ESBL producers. Resistance genes such as\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M<\/jats:sub>\n                    ,\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>TEM<\/jats:sub>\n                    , and\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>OXA<\/jats:sub>\n                    were detected in 207 (94.1%), 99 (45%), and 53 (24.1%) isolates, respectively. Three types of integron I and one type of integron II were identified in 13 (5.9%) and 2 (0.9%) isolates, respectively. The integrons encompassed 10 different genes:\n                    <jats:italic toggle=\"yes\">dfrA1\/12\/17\/25<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">aadA1\/2\/5<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">sat2<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">orfF<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">ybeA<\/jats:italic>\n                    . Our study underscores concern for increasing CRO resistance, and highlights the widespread ESBL genes in\n                    <jats:italic toggle=\"yes\">Salmonella enterica<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1089\/fpd.2018.2468","type":"journal-article","created":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T11:06:15Z","timestamp":1543489575000},"page":"770-775","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Increase in Ceftriaxone Resistance and Widespread Extended-Spectrum \u03b2-Lactamases Genes Among\n                    <i>Salmonella enterica<\/i>\n                    from Human and Nonhuman Sources"],"prefix":"10.1177","volume":"15","author":[{"given":"Dai","family":"Kuang","sequence":"first","affiliation":[{"name":"Shanghai Jiao Tong University","place":["China"]},{"name":"University of Maryland"},{"name":"University of Maryland"},{"name":"University of Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianmin","family":"Zhang","sequence":"additional","affiliation":[{"name":"South China Agricultural University","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuebin","family":"Xu","sequence":"additional","affiliation":[{"name":"Shanghai Municipal Center for Disease Control and Prevention","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weimin","family":"Shi","sequence":"additional","affiliation":[{"name":"Shanghai Municipal Ke-Ma-Jia Technology Center for Microbiology","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowei","family":"Yang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xudong","family":"Su","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianming","family":"Shi","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianghong","family":"Meng","sequence":"additional","affiliation":[{"name":"University of Maryland"},{"name":"University of Maryland"},{"name":"University of Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,12,11]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46725-0"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01054-07"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2005.12.029"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/107662903765826804"},{"key":"e_1_3_3_6_1","volume-title":"National Antimicrobial Resistance Monitoring System for Enteric Bacteria (NARMS): Human Isolates Final Report, 2013","author":"CDC","year":"2015","unstructured":"CDC. 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