{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:34:14Z","timestamp":1777642454746,"version":"3.51.4"},"reference-count":50,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foodborne Pathogens and Disease"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>\n                      This study aimed to trace the transmission source of\n                      <jats:italic toggle=\"yes\">Salmonella enterica<\/jats:italic>\n                      serovar Typhimurium and\n                      <jats:italic toggle=\"yes\">Salmonella enterica<\/jats:italic>\n                      serovar Enteritidis strains associated with enteric infections in Shanghainese children, and understand the molecular mechanism of resistance to third-generation cephalosporins and ciprofloxacin.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>The profiles of pulsed-field gel electrophoresis (PFGE) were compared among the isolates from children, animal, and environment. Antimicrobial susceptibility was determined using the minimal inhibitory concentrations and Kirby\u2013Bauer disk diffusion method. Extended-spectrum \u03b2-lactamase (ESBL) producing isolates mediated by resistance genes were identified using polymerase chain reaction and sequencing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Based on PFGE patterns, 49 (33.1%) of 148 human\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      Typhimurium isolates located in the dominant PFGE clusters were genetically related to the isolates from poultry source, environment water, aquatic products, and reptiles, whereas 97 (97.0%) of 100 human\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      Enteritidis isolates were genetically related to isolates from poultry and water. The rates of resistance to ceftriaxone among clinical\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      Typhimurium and\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      Enteritidis isolates were 42.0% and 14.2%, respectively. Besides, 35.1% of\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      Typhimurium isolates displayed resistance to ciprofloxacin; 64.9% of\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      Typhimurium isolates and 97.0% of\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      Enteritidis isolates displayed reduced susceptibility to ciprofloxacin. Of 64 ESBL\/AmpC-producing strains, CTX-M, TEM, DHA, and CMY were detected at frequencies of 86.0%, 62.5%, 7.8%, 3.1%, and 3.1%, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      The transmission sources of\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      Typhimurium and\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      Enteritidis infections in Shanghainese children were diverse. The high prevalence of resistance to third-generation cephalosporins and ciprofloxacin mediated by multiple molecular mechanisms needs continuous monitoring and intervention.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/fpd.2018.2557","type":"journal-article","created":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T15:55:45Z","timestamp":1550591745000},"page":"244-255","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":42,"title":["<i>Salmonella<\/i>\n                    Typhimurium and\n                    <i>Salmonella<\/i>\n                    Enteritidis Infections in Sporadic Diarrhea in Children: Source Tracing and Resistance to Third-Generation Cephalosporins and Ciprofloxacin"],"prefix":"10.1177","volume":"16","author":[{"given":"Zhougqiu","family":"Wei","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Children's Hospital of Fudan University, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuebin","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Shanghai Municipal Center For Disease Control and Prevention, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meiying","family":"Yan","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hailing","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Children's Hospital of Fudan University, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuefang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Children's Hospital of Fudan University, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biao","family":"Kan","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Children's Hospital of Fudan University, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,4,10]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2015.12.004"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2106.140999"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2005.12.029"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.10.4579-4587.1998"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-17-068"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000001562"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16003-0"},{"key":"e_1_3_3_9_1","volume-title":"Performance standards for antimicrobial susceptibility testing; Twenty-sixth informational supplement. 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